Assessment of bone marrow-derived Cellular Therapy in progressive Multiple Sclerosis (ACTiMuS): Study protocol for a randomised controlled trial

Trials

Volumn 16, Issue 1, 2015, Pages

  Rice, Claire M ^a,b   Marks, David I ^c   Ben Shlomo, Yoav ^a   Evangelou, Nikos ^d   Morgan, Paul S ^d   Metcalfe, Chris ^a   Walsh, Peter ^b   Kane, Nick M ^b   Guttridge, Martin G ^e   Miflin, Gail ^e   Blackmore, Stuart ^e   Sarkar, Pamela ^a,b   Redondo, Juliana ^a   Owen, Denise ^b   Cottrell, David A ^b   Wilkins, Alastair ^a,b   Scolding, Neil J ^a,b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

^c BRISTOL ROYAL HOSPITAL FOR CHILDREN   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

Bone marrow; Cellular therapy; Global evoked potentials; Progressive multiple sclerosis; Reparative therapy; Stem cell

Indexed keywords

ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; CLINICAL EFFECTIVENESS; CLINICAL PROTOCOL; EVALUATION AND FOLLOW UP; EVOKED RESPONSE; EXPANDED DISABILITY STATUS SCALE; FOLLOW UP; HUMAN; INTENTION TO TREAT ANALYSIS; METHODOLOGY; MULTIPLE SCLEROSIS; MULTIPLE SCLEROSIS FUNCTIONAL COMPOSITE; MULTIPLE SCLEROSIS IMPACT SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL COHERENCE TOMOGRAPHY; OUTCOME ASSESSMENT; PACED AUDITORY SERIAL ADDITION TEST; PATIENT PARTICIPATION; PATIENT SAFETY; PHASE 1 CLINICAL TRIAL (TOPIC); PHLEBOTOMY; PROSPECTIVE STUDY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESEARCH SUBJECT; UNITED KINGDOM; ADVERSE EFFECTS; AUTOTRANSPLANTATION; BONE MARROW TRANSPLANTATION; BRAIN; CONTROLLED STUDY; CONVALESCENCE; DOUBLE BLIND PROCEDURE; ENGLAND; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; NERVE CONDUCTION; NEUROLOGIC EXAMINATION; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; REACTION TIME; SPINAL CORD; TIME FACTOR; TREATMENT OUTCOME;

BONE MARROW TRANSPLANTATION; BRAIN; CLINICAL PROTOCOLS; DOUBLE-BLIND METHOD; ENGLAND; EVOKED POTENTIALS; HUMANS; INTENTION TO TREAT ANALYSIS; MAGNETIC RESONANCE IMAGING; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; NEURAL CONDUCTION; NEUROLOGIC EXAMINATION; PROSPECTIVE STUDIES; REACTION TIME; RECOVERY OF FUNCTION; RESEARCH DESIGN; SPINAL CORD; TIME FACTORS; TOMOGRAPHY, OPTICAL COHERENCE; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 84944414746     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/s13063-015-0953-1     Document Type: Article

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