Genotoxicity, acute and subchronic toxicity studies of nano liposomes of Orthosiphon stamineus ethanolic extract in Sprague Dawley rats

BMC Complementary and Alternative Medicine

Volumn 15, Issue 1, 2015, Pages

  Shafaei, Armaghan ^a   Esmailli, Kameh ^a   Farsi, Elham ^b   Aisha, Abdalrahim F A ^a   Abul Majid, Amin Malik Shah ^b   Ismail, Zhari ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b SCHOOL OF PHYSICS   (Malaysia)

Author keywords

Genotoxicity; Nano liposomes; OECD; Oral Toxicity; Orthosiphon stamineus

Indexed keywords

ALCOHOL; ARSENIC; CADMIUM; FLAVONE; LEAD; LIPOSOME; ORTHOSIPHON STAMINEUS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; AMES TEST; ANIMAL EXPERIMENT; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BACTERIAL STRAIN; CHRONIC TOXICITY; CONTROLLED STUDY; DRUG STRUCTURE; FEMALE; GENOTOXICITY; HEMATOLOGICAL PARAMETERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LD50; LIPOPHILICITY; MALE; MEDICINAL PLANT; MORTALITY; NONHUMAN; ORGAN WEIGHT; ORTHOSIPHON STAMINEUS; RAT; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SOUTHEAST ASIA; WEIGHT CHANGE; ANIMAL; BIOAVAILABILITY; BODY WEIGHT; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; MUTAGEN TESTING; ORAL DRUG ADMINISTRATION; ORGAN SIZE; ORTHOSIPHON; SOLUBILITY; SPRAGUE DAWLEY RAT; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BODY WEIGHT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FEMALE; LETHAL DOSE 50; LIPOSOMES; MUTAGENICITY TESTS; ORGAN SIZE; ORTHOSIPHON; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM; SOLUBILITY; TOXICITY TESTS;

EID: 84944402696     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-015-0885-z     Document Type: Article

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