Simultaneous analysis of bioactive markers from Orthosiphon stamineus benth leaves extracts by reverse phase high performance liquid chromatography

Tropical Journal of Pharmaceutical Research

Volumn 10, Issue 1, 2011, Pages 97-103

  Siddiqui, Mohammad Jamshed Ahmad ^a   Ismail, Zhari ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

HPLC; Isocratic; Orthosiphol A; Orthosiphon stamineus; Quantification; Rosmarinic acid; Sinensetin

Indexed keywords

3' HYDROXY 5, 6, 7, 4' TETRAMETHOXYFLAVONE; 5, 6, 7, 3', 4' PENTAMETHOXYFLAVONE; ORTHOSIPHOL A; ORTHOSIPHON STAMINEUS EXTRACT; PETROLEUM; PLANT EXTRACT; ROSMARINIC ACID; TETRAHYDROFURAN; UNCLASSIFIED DRUG; WATER;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; FLOW RATE; NONHUMAN; ORTHOSIPHON; ORTHOSIPHON STAMINEUS; PARTICLE SIZE; PHYTOCHEMISTRY; PLANT LEAF; QUANTITATIVE ANALYSIS; REACTION TIME; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLVENT EXTRACTION; ULTRAVIOLET RADIATION;

EID: 79951807593     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Tiktinskii OL, Bablumian IA. Therapeutic action of Java tea and field horsetail in uric acid diathesis. Urol Nefrol (Mosk). Russian; 1983; p 47
2. Wiart C. Orthosiphon stamineus Benth. In: Medicinal Plants of Southeast Asia. Wong FK, Ed. Prentice Hall, Kuala Lumpur, 2002; p 265
3. Dat DD, Ham NN, Khac DH, Lam N, Son TPT, Dau NV, Grabe M Johansson R Lindgren G and Stjernstrom NE. Studies on the individual and combined diuretic effects of four Vietnamese traditional herbal remedies (Zea mays, Imperata cylindrical, Plantago major and Orthosiphon stamineus). J Ethnopharmacol 1992; 36: 225-231.
4. Tezuka Y, Stampoulis P, Banskota AH, Awale S, Tran KQ, Saiki S, Kadota S. Constituents of the Vietnamese Medicinal Plant Orthosiphon stamineus. Chem Pharm Bull 2000; 48: 1711-1719.
5. Awale S, Tezuka Y, Banskota AH, Kouda K, Tun KM, Kadota S. Five novel highly oxygenated diterpenes of Orthosiphon stamineus from Myanmar. J Nat Prod 2001; 64: 592-596.
6. Malterud KE, Hanche-Olsen IM, Smith-Kiekkand I. Flavonoids from Orthosiphon spicatus. Planta Med 1989; 55: 569-570.
7. Sumaryono W, Proksch P, Wravy V, Witte L, Hartmann T. Qualitative and Quantitative Analysis of the Phenolic Constituents from Orthosiphon stamineus. Planta Med 1991; 57: 176-180.
8. Masuda T, Masuda K, Nakatani N. Orthosiphol A - a highly oxygenated diterpene from the leaves of Orthosiphon stamineus. Tetrahedron Lett 1992; 33: 945-946.
9. Olah NK, Radu L, Mogoan C, Hanganu D, Gocan S. Phytochemical and pharmacological studies on Orthosiphon stamineus Benth.(Lamiaceae) hydro alcoholic extracts. J Pharm Biomed Anal 2003; 33: 117-123.
10. Hossain M A, Ismail Z. Hydroxy betulinic acid from the leaves of Orthosiphon stamineus. ACGC Chem.Res.Commun. 2003; 16: 69-73.
11. Hossain MA, Salehuddin SM, Ismail Z. Rosmarinic acid and methyl rosmarinate from Orthosiphon stamineus Benth. J Bangladesh Acad Sci 2006; 30: 167-172.
12. Akowuah GA, Ismail Z, Norhayati I, Sadikun A, Khamsah SM. Sinensetin, eupatorin, 3'- hydroxy-5, 6, 7, 4'-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of Orthosiphon stamineus from Malaysia. Food Chem 2004; 87: 559-566.
13. Sahib HB, Aisha AF, Yam MF, Asmawi MZ, Ismail Z, Salhimi S M, Othman NH, Abdul Majid A M S. Anti-angiogenic and antioxidant properties of Orthosiphon stamineus Benth. Methanolic leaves extract. Int J. Pharmacol 2009; 5(2): 162-167.
14. Akowuah GA, Ismail Z, Norhayati I, Sadikun A. The effects of different extraction solvents of varying polarities on polyphenols of orthosiphon stamineus and evaluation of the free radical-scavenging activity. Food Chem 2005; 93: 311-317.
15. Pietta PG, Mauri PL, Gardana C, Bruno A. Highperformance liquid chromatography with diodearray ultraviolet detection of methoxylated flavones in Orthosiphon leaves. J Chromatogr A 1991; 547: 439-442.
16. Mouly P, Gaydou EM, Auffray A. Simultaneous separation of flavanone glycosides and polymethoxylated flavones in citrus juices using liquid chromatography. J Chromatogr A 1998; 800: 171-179.
17. Siddiqui M J, Hafizoh S N, Ismail Z, Sahib HB, Helal MHS, Majid AMS. Analysis of Total proteins, polysaccharides and glycosaponins contents of Orthosiphon stamineus Benth. In spray and Freeze dried methanol: water (1:1) extract and its contribution to cytotoxic and angiogenic activities. Phcog Res. 2009; 1(5): 320-326.