Long non-coding RNA ANRIL is up-regulated in bladder cancer and regulates bladder cancer cell proliferation and apoptosis through the intrinsic pathway

Biochemical and Biophysical Research Communications

Volumn 467, Issue 2, 2015, Pages 223-228

  Zhu, Hongxue ^a,b   Li, Xuechao ^a   Song, Yarong ^a   Zhang, Peng ^a   Xiao, Yajun ^a   Xing, Yifei ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Hospital of Xinjiang Production and Construction Corps   (China)

Author keywords

ANRIL; Apoptosis; Bladder cancer; Proliferation; The intrinsic pathway

Indexed keywords

ANTISENSE NON CODING RNA IN THE INK4 LOCUS; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; CYTOPLASM PROTEIN; LONG UNTRANSLATED RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANRIL LONG NON-CODING RNA, HUMAN; BAX PROTEIN, MOUSE; BCL2 PROTEIN, MOUSE; CARRIER PROTEIN; DIABLO PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLADDER CANCER; BLADDER CANCER CELL LINE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ADENOCARCINOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BLADDER TUMOR; CANCER TRANSPLANTATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARRIER PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIAL PROTEINS; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, LONG NONCODING; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; URINARY BLADDER NEOPLASMS;

EID: 84944393844     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.10.002     Document Type: Article

References (30)

1. L.A. Torre, F. Bray, R.L. Siegel, J. Ferlay, J. Lortet-Tieulent, and A. Jemal Global cancer statistics, 2012, CA Cancer J. Clin. 65 2015 87 108
2. D.S. Kaufman, W.U. Shipley, and A.S. Feldman Bladder cancer Lancet 374 2009 239 249
3. V.A. Moran, R.J. Perera, and A.M. Khalil Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs Nucleic Acids Res. 40 2012 6391 6400
4. J. Okamoto, T. Hirata, Z. Chen, H.M. Zhou, I. Mikami, H. Li, A. Yagui-Beltran, M. Johansson, L.M. Coussens, G. Clement, Y. Shi, F. Zhang, K. Koizumi, K. Shimizu, D. Jablons, and B. He EMX2 is epigenetically silenced and suppresses growth in human lung cancer Oncogene 29 2010 5969 5975
5. J.C. Scheuermann, and L.A. Boyer Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease EMBO J. 32 2013 1805 1816
6. M. Mourtada-Maarabouni, M.R. Pickard, V.L. Hedge, F. Farzaneh, and G.T. Williams GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer Oncogene 28 2009 195 208
7. C. Braconi, T. Kogure, N. Valeri, N. Huang, G. Nuovo, S. Costinean, M. Negrini, E. Miotto, C.M. Croce, and T. Patel microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer Oncogene 30 2011 4750 4756
8. T. Gutschner, M. Hammerle, M. Eissmann, J. Hsu, Y. Kim, G. Hung, A. Revenko, G. Arun, M. Stentrup, M. Gross, M. Zornig, A.R. MacLeod, D.L. Spector, and S. Diederichs The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells Cancer Res. 73 2013 1180 1189
9. M. Svoboda, J. Slyskova, M. Schneiderova, P. Makovicky, L. Bielik, M. Levy, L. Lipska, B. Hemmelova, Z. Kala, M. Protivankova, O. Vycital, V. Liska, L. Schwarzova, L. Vodickova, and P. Vodicka HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients Carcinogenesis 35 2014 1510 1515
10. E. Pasmant, I. Laurendeau, D. Heron, M. Vidaud, D. Vidaud, and I. Bieche Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF Cancer Res. 67 2007 3963 3969
11. C.H. Li, and Y. Chen Targeting long non-coding RNAs in cancers: progress and prospects Int. J. Biochem. Cell Biol. 45 2013 1895 1910
12. K. Tano, and N. Akimitsu Long non-coding RNAs in cancer progression Front. Genet. 3 2012 219
13. L. Hua, C.Y. Wang, K.H. Yao, J.T. Chen, J.J. Zhang, and W.L. Ma High expression of long non-coding RNA ANRIL is associated with poor prognosis in hepatocellular carcinoma Int. J. Clin. Exp. Pathol. 8 2015 3076 3082
14. M.D. Huang, W.M. Chen, F.Z. Qi, R. Xia, M. Sun, T.P. Xu, L. Yin, E.B. Zhang, W. De, and Y.Q. Shu Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2 J. Hematol. Oncol. 8 2015 50
15. Y.H. Kang, D. Kim, and E.J. Jin Down-regulation of phospholipase D stimulates death of lung cancer cells involving up-regulation of the long ncRNA ANRIL Anticancer Res. 35 2015 2795 2803
16. L. Lin, Z.T. Gu, W.H. Chen, and K.J. Cao Increased expression of the long non-coding RNA ANRIL promotes lung cancer cell metastasis and correlates with poor prognosis Diagn. Pathol. 10 2015 14
17. F.Q. Nie, M. Sun, J.S. Yang, M. Xie, T.P. Xu, R. Xia, Y.W. Liu, X.H. Liu, E.B. Zhang, K.H. Lu, and Y.Q. Shu Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression Mol. Cancer Ther. 14 2015 268 277
18. J.J. Qiu, Y.Y. Lin, J.X. Ding, W.W. Feng, H.Y. Jin, and K.Q. Hua Long non-coding RNA ANRIL predicts poor prognosis and promotes invasion/metastasis in serous ovarian cancer Int. J. Oncol. 46 2015 2497 2505
19. E.B. Zhang, R. Kong, D.D. Yin, L.H. You, M. Sun, L. Han, T.P. Xu, R. Xia, J.S. Yang, W. De, and J. Chen Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a Oncotarget 5 2014 2276 2292
20. D. Chen, Z. Zhang, C. Mao, Y. Zhou, L. Yu, Y. Yin, S. Wu, X. Mou, and Y. Zhu ANRIL inhibits p15(INK4b) through the TGFbeta1 signaling pathway in human esophageal squamous cell carcinoma Cell. Immunol. 289 2014 91 96
21. Y. Kotake, T. Nakagawa, K. Kitagawa, S. Suzuki, N. Liu, M. Kitagawa, and Y. Xiong Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene Oncogene 30 2011 1956 1962
22. G. Wan, R. Mathur, X. Hu, Y. Liu, X. Zhang, G. Peng, and X. Lu Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway Cell. Signal 25 2013 1086 1095
23. G.S. Salvesen, and C.S. Duckett IAP proteins: blocking the road to death's door Nat. Rev. Mol. Cell Biol. 3 2002 401 410
24. E. Varfolomeev, and D. Vucic Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets Future Oncol. 7 2011 633 648
25. M. Elkin, A. Shevelev, E. Schulze, M. Tykocinsky, M. Cooper, I. Ariel, D. Pode, E. Kopf, N. de Groot, and A. Hochberg The expression of the imprinted H19 and IGF-2 genes in human bladder carcinoma FEBS Lett. 374 1995 57 61
26. M. Luo, Z. Li, W. Wang, Y. Zeng, Z. Liu, and J. Qiu Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression Cancer Lett. 333 2013 213 221
27. I. Ariel, M. Sughayer, Y. Fellig, G. Pizov, S. Ayesh, D. Podeh, B.A. Libdeh, C. Levy, T. Birman, M.L. Tykocinski, N. de Groot, and A. Hochberg The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma Mol. Pathol. 53 2000 320 323
28. K. Fernald, and M. Kurokawa Evading apoptosis in cancer Trends Cell Biol. 23 2013 620 633
29. A. Gross, J.M. McDonnell, and S.J. Korsmeyer BCL-2 family members and the mitochondria in apoptosis Genes Dev. 13 1999 1899 1911
30. J.C. Martinou, and R.J. Youle Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics Dev. Cell 21 2011 92 101