Association of osteolytic lesions, bone mineral loss and trabecular sclerosis with prevalent vertebral fractures in patients with multiple myeloma

European Journal of Radiology

Volumn 84, Issue 11, 2015, Pages 2269-2274

  Borggrefe, J ^a   Giravent, S ^b   Campbell, G ^b   Thomsen, F ^c   Chang, D ^a   Franke, M ^a   Gunther A ^b   Heller, M ^d   Wulff, A ^b  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Bone mineral density; Bone structure; Key words Multiple myeloma; Osteolytic lesions; Vertebral fracture

Indexed keywords

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BONE ATROPHY; BONE DENSITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; OSTEOSCLEROSIS; PREVALENCE; PRIORITY JOURNAL; RADIATION DOSE; RADIOLOGIST; RECEIVER OPERATING CHARACTERISTIC; SPINE FRACTURE; TRABECULAR BONE; WHOLE BODY SCINTISCANNING; COMPLICATION; FRAGILITY FRACTURE; LUMBAR VERTEBRA; MIDDLE AGED; OSTEOLYSIS; PATHOLOGY; PROCEDURES; RADIOGRAPHY; SCLEROSIS; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; BONE DENSITY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; MULTIPLE MYELOMA; OSTEOLYSIS; OSTEOPOROTIC FRACTURES; PREVALENCE; ROC CURVE; SCLEROSIS; SPINAL FRACTURES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84944352246     PISSN: 0720048X     EISSN: 18727727     Source Type: Journal    
DOI: 10.1016/j.ejrad.2015.07.024     Document Type: Article

References (30)

1. M.S. Raab, K. Podar, I. Breitkreutz, P.G. Richardson, and K.C. Anderson Multiple myeloma Lancet 374 9686 2009 324 339
2. R. Bartl, and A. Fateh-Moghadam The diagnosis of multiple myeloma Onkologie 9 4 1986 183 188 90-5
3. L.J. Melton, K. 3rd, R.A. yle, S.J. Achenbach, A.L. Oberg, and S.V. Rajkumar Fracture risk with multiple myeloma: a population-based study J. Bone Miner. Res. 20 3 2005 487 493
4. L.J. Melton, R. 3rd, S.V. ajkumar, S. Khosla, S.J. Achenbach, A.L. Oberg, and R.A. Kyle Fracture risk in monoclonal gammopathy of undetermined significance J. Bone Miner. Res. 19 1 2004 25 30
5. M.N. Vogel, K. Weisel, O. Maksimovic, and et al. Pathologic fractures in patients with multiple myeloma undergoing bisphosphonate therapy: incidence and correlation with course of disease AJR 193 3 2009 656 661
6. R.A. Kyle, M.A. Gertz, T.E. Witzig, and et al. Review of 1027 patients with newly diagnosed multiple myeloma Mayo Clin. Proc. 78 1 2003 21 33
7. M.V. Dhodapkar, R. Weinstein, G. Tricot, and et al. Biologic and therapeutic determinants of bone mineral density in multiple myeloma Leukemia Lymphoma 32 1-2 1998 121 127
8. M. Laroche, O. Lemaire, P. Bourin, and et al. Dual-energy X-ray absorptiometry and biochemical markers of bone turnover after autologous stem cell transplantation in myeloma Eur. J. Haematol. 88 5 2012 388 395
9. M. Laroche, J.M. Pouilles, C. Dromer, M. Attal, and C. Ribot Dual-energy X-ray absorptiometry in patients with multiple myeloma and benign gammopathies Clin. Exp. Rheumatol. 14 1 1996 108
10. X. Mariette, C. Bergot, P. Ravaud, and et al. Evolution of bone densitometry in patients with myeloma treated with conventional or intensive therapy Cancer 76 9 1995 1559 1563
11. R. Coleman, J.J. Body, M. Aapro, P. Hadji, and J. Herrstedt Bone health in cancer patients: ESMO clinical practice guidelines Ann. Oncol. 2014 1 14
12. S. Delorme, and A. Baur-Melnyk Imaging in multiple myeloma Eur. J. Radiol. 70 3 2009 401 408
13. A.P. Winterbottom, and A.S. Shaw Imaging patients with myeloma Clin. Radiol. 64 1 2009 1 11
14. B.G. Durie, and S.E. Salmon A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival Cancer 36 3 1975 842 854
15. H. Taneichi, K. Kaneda, N. Takeda, K. Abumi, and S. Satoh Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine Spine 22 3 1997 239 245
16. T.M. Keaveny Biomechanical computed tomography-noninvasive bone strength analysis using clinical computed tomography scans Ann. N. Y. Acad. Sci. 1192 2010 57 65
17. M. Dimopoulos, R. Kyle, J.P. Fermand, and et al. Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3 Blood 117 18 2011 4701 4705
18. M. Dimopoulos, E. Terpos, R.L. Comenzo, and et al. International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma Leukemia 23 9 2009 1545 1556
19. M. Horger, C.D. Claussen, U. Bross-Bach, and et al. Whole-body low-dose multidetector row-CT in the diagnosis of multiple myeloma: an alternative to conventional radiography Eur. J. Radiol. 54 2 2005 289 297
20. M. Horger, L. Kanz, B. Denecke, and et al. The benefit of using whole-body, low-dose, nonenhanced, multidetector computed tomography for follow-up and therapy response monitoring in patients with multiple myeloma Cancer 109 8 2007 1617 1626
21. E.J. Angtuaco, A.B. Fassas, R. Walker, R. Sethi, and B. Barlogie Multiple myeloma: clinical review and diagnostic imaging Radiology 231 1 2004 11 23
22. C. Graeff, F. Marin, H. Petto, and et al. High resolution quantitative computed tomography-based assessment of trabecular microstructure and strength estimates by finite-element analysis of the spine, but not DXA, reflects vertebral fracture status in men with glucocorticoid-induced osteoporosis Bone 52 2 2013 568 577
23. C. Graeff, W. Timm, T.N. Nickelsen, and et al. Monitoring teriparatide-associated changes in vertebral microstructure by high-resolution CT in vivo: results from the EUROFORS study J. Bone Miner. Res. 22 9 2007 1426 1433
24. A. Krebs, C. Graeff, I. Frieling, and et al. High resolution computed tomography of the vertebrae yields accurate information on trabecular distances if processed by 3D fuzzy segmentation approaches Bone 44 1 2009 145 152
25. E. deLong, D.M. deLong, and D. Clarke Pearson Comparing the areas under two or more correlated ROC curves Biometrics 44 3 1988 837 845
26. E. Terpos, G. Morgan, M.A. Dimopoulos, and et al. International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease J. Clin. Oncol. 31 18 2013 2347 2357
27. F. Saad, A. Lipton, R. Cook, Y.M. Chen, M. Smith, and R. Coleman Pathologic fractures correlate with reduced survival in patients with malignant bone disease Cancer 110 8 2007 1860 1867
28. M. Sonmez, T. Akagun, M. Topbas, and et al. Effect of pathologic fractures on survival in multiple myeloma patients: a case control study J. Exp. Clin. Cancer Res. 27 2008 11
29. M. Laroche, O. Lemaire, P. Bourin, and et al. Dual-energy X-ray absorptiometry and biochemical markers of bone turnover after autologous stem cell transplantation in myeloma Eur. J. Haematol. 88 5 2015 388 395
30. M. Takasu, C. Tani, M. Ishikawa, and et al. Multiple myeloma: microstructural analysis of lumbar trabecular bones in patients without visible bone lesions?preliminary results Radiology 260 2 2011 472 479