Pathologic fractures in patients with multiple myeloma undergoing bisphosphonate therapy: Incidence and correlation with course of disease

American Journal of Roentgenology

Volumn 193, Issue 3, 2009, Pages 656-661

  Vogel, Monika N ^a   Weisel, Katja ^a   Maksimovic, Olga ^a   Peters, Sebastian ^a   Brodoefel, Harald ^a   Claussen, Claus D ^a   Horger, Marius S ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

CT; Multiple myeloma; Pathologic fracture

Indexed keywords

PAMIDRONIC ACID; ZOLEDRONIC ACID;

ADULT; AGED; ARTICLE; BLOOD EXAMINATION; COMPRESSION FRACTURE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIPLE MYELOMA; PATHOLOGIC FRACTURE; PRIORITY JOURNAL; REMISSION; WHOLE BODY CT;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BONE DENSITY CONSERVATION AGENTS; CHI-SQUARE DISTRIBUTION; DIPHOSPHONATES; FEMALE; FRACTURES, SPONTANEOUS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIPLE MYELOMA; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; RETROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 69949094339     PISSN: 0361803X     EISSN: None     Source Type: Journal    
DOI: 10.2214/AJR.08.2002     Document Type: Article

References (16)

1. Durie BG. Staging and kinetics of multiple myeloma. Clin Haematol 1986; 11:3-18
2. Ishida T, Dorfman H. Plasma cell myeloma in unusually young patients: a report of two cases and review of the literature. Skeletal Radiol 1995; 24:47-51
3. Riccardi A, Gobbi P, Ucci G, et al. Changing clinical presentation of multiple myeloma. Eur J Cancer 1991; 27:1401-1405
4. Saad F, Lipton A, Cook R, Chen YM, Smith M, Coleman R. Pathologic fractures correlate with reduced survival in patients with malignant bone disease. Cancer 2007; 110:1860-1867 (Pubitemid 47557312)
5. Berenson JR, Lichtenstein A, Porter L, et al. Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. N Engl J Med 1996; 334:488-493 (Pubitemid 26067736)
6. Kyle RA, Yee GC, Somerfield MR, et al. American Society of Clinical Oncology 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma. J Clin Oncol 2007; 25:2464-2472
7. Berenson JR, Lichtenstein A, Porter L, et al. Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. J Clin Oncol 1998; 16:593-602 (Pubitemid 28135605)
8. Blade J, Samson D, Reece D, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the European Group for Blood and Marrow Transplant. Br J Haematol 1998; 102:1115-1123
9. Saad F, Olsson C, Schulman C, et al. Skeletal morbidity in men with prostate cancer: quality-of-life considerations throughout the continuum of care. Eur Urol 2004; 46:731-740 (Pubitemid 39488403)
10. Melton LJ 3rd, Kyle RA, Achenbach SJ, Oberg AL, Rajkumar SV. Fracture risk with multiple myeloma: a population based study. J Bone Miner Res 2005; 20:487-493
11. Mahnken AH, Wildberger JE, Gehbauer G, et al. Multidetector CT of the spine in multiple myeloma: comparison with MR imaging and radiography. AJR 2002; 178:1429-1436 (Pubitemid 34547826)
12. Roodman GD. Treatment strategies for bone disease. Bone Marrow Transplant 2007; 40:1139-1146
13. Horger M, Claussen CD, Bross-Bach U, et al. Whole-body low-dose multidetector row-CT in the diagnosis of multiple myeloma: an alternative to conventional radiography. Eur J Radiol 2005; 54:289-297 (Pubitemid 40523623)
14. Epstein J, Walker R. Myeloma and bone disease: "the dangerous tango." Clin Adv Hematol Oncol 2006; 4:300-306
15. Dhodapkar MV, Singh J, Mehta J, et al. Anti-myeloma activity of pamidronate in vivo. Br J Haematol 1998; 103:530-532
16. Lecouvet FE, Vande Berg BC, Michaux L, Jamart J, Maldague BE, Malghem J. Development of vertebral fractures in patients with multiple myeloma: does MRI enable recognition of vertebrae that will collapse? J Comput Assist Tomogr 1998; 22:430-436 (Pubitemid 28396738)