메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

CELLS AND CELL COMPONENTS; DISABILITY; INJURY; INTERFACE; PHENOTYPE; PROTEIN; RODENT;

EID: 84944346028     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9574     Document Type: Article
Times cited : (62)

References (44)
  • 2
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • Wynn, T. A. & Ramalingam, T. R. Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat. Med. 18, 1028-1040 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 3
    • 79952340427 scopus 로고    scopus 로고
    • Remodeling and homeostasis of the extracellular matrix: Implications for fibrotic diseases and cancer
    • Cox, T. R. & Erler, J. T. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis. Model. Mech. 4, 165-178 (2011).
    • (2011) Dis. Model. Mech. , vol.4 , pp. 165-178
    • Cox, T.R.1    Erler, J.T.2
  • 4
    • 84859073207 scopus 로고    scopus 로고
    • Recent developments in myofibroblast biology: Paradigms for connective tissue remodeling
    • Hinz, B. et al. Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am. J. Pathol. 180, 1340-1355 (2011).
    • (2011) Am. J. Pathol. , vol.180 , pp. 1340-1355
    • Hinz, B.1
  • 5
    • 65549160523 scopus 로고    scopus 로고
    • Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis
    • Hinz, B. Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: implications for the pathogenesis and treatment of fibrosis. Curr. Rheumatol. Rep. 11, 120-126 (2009).
    • (2009) Curr. Rheumatol. Rep. , vol.11 , pp. 120-126
    • Hinz, B.1
  • 6
    • 77955914547 scopus 로고    scopus 로고
    • Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
    • Liu, F. et al. Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J. Cell Biol. 190, 693-706 (2010).
    • (2010) J. Cell Biol. , vol.190 , pp. 693-706
    • Liu, F.1
  • 7
    • 78650412961 scopus 로고    scopus 로고
    • Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation
    • Du, F. et al. Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation. Cancer Res. 70, 10080-10089 (2010).
    • (2010) Cancer Res. , vol.70 , pp. 10080-10089
    • Du, F.1
  • 8
    • 84875535234 scopus 로고    scopus 로고
    • The immunology of fibrosis
    • Wick, G. et al. The immunology of fibrosis. Annu. Rev. Immunol. 31, 107-135 (2013).
    • (2013) Annu. Rev. Immunol. , vol.31 , pp. 107-135
    • Wick, G.1
  • 9
    • 0035182849 scopus 로고    scopus 로고
    • Viscoelastic properties of human skin and processed dermis
    • Silver, F. H., Freeman, J. W. & DeVore, D. Viscoelastic properties of human skin and processed dermis. Skin Res. Technol. 7, 18-23 (2001).
    • (2001) Skin Res. Technol. , vol.7 , pp. 18-23
    • Silver, F.H.1    Freeman, J.W.2    DeVore, D.3
  • 10
    • 0345055316 scopus 로고    scopus 로고
    • The role of elastin in aortic valve mechanics
    • Vesely, I. The role of elastin in aortic valve mechanics. J. Biomech. 31, 115-123 (1998).
    • (1998) J. Biomech. , vol.31 , pp. 115-123
    • Vesely, I.1
  • 11
    • 0037153007 scopus 로고    scopus 로고
    • Viscoelastic properties of young and old human dermis: A proposed molecular mechanism for elastic energy storage in collagen and elastin
    • Silver, F. H., Seehra, G. P., Freeman, J. W. & DeVore, D. Viscoelastic properties of young and old human dermis: A proposed molecular mechanism for elastic energy storage in collagen and elastin. J. Appl. Polym. Sci. 86, 1978-1985 (2002).
    • (2002) J. Appl. Polym. Sci. , vol.86 , pp. 1978-1985
    • Silver, F.H.1    Seehra, G.P.2    Freeman, J.W.3    DeVore, D.4
  • 12
    • 0025916022 scopus 로고
    • Extracellular microfibrils are increased in localized and systemic scleroderma skin
    • Fleischmajer, R., Jacobs, L., Schwartz, E. & Sakai, L. Y. Extracellular microfibrils are increased in localized and systemic scleroderma skin. Lab. Invest. 64, 791-798 (1991).
    • (1991) Lab. Invest. , vol.64 , pp. 791-798
    • Fleischmajer, R.1    Jacobs, L.2    Schwartz, E.3    Sakai, L.Y.4
  • 13
    • 0029448121 scopus 로고
    • Elastin in lung development and disease
    • discussion 212-194
    • Pierce, R. A., Mariani, T. J. & Senior, R. M. Elastin in lung development and disease. Ciba Found. Symp. 192, 199-212 discussion 212-194 (1995).
    • (1995) Ciba Found. Symp. , vol.192 , pp. 199-212
    • Pierce, R.A.1    Mariani, T.J.2    Senior, R.M.3
  • 14
    • 0037050030 scopus 로고    scopus 로고
    • Fibulin-5/DANCE is essential for elastogenesis in vivo
    • Nakamura, T. et al. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature 415, 171-175 (2002).
    • (2002) Nature , vol.415 , pp. 171-175
    • Nakamura, T.1
  • 15
    • 0037049996 scopus 로고    scopus 로고
    • Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo
    • Yanagisawa, H. et al. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature 415, 168-171 (2002).
    • (2002) Nature , vol.415 , pp. 168-171
    • Yanagisawa, H.1
  • 16
    • 0242670018 scopus 로고    scopus 로고
    • Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions
    • Toda, M. et al. Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions. J. Allergy Clin. Immunol. 111, 875-881 (2003).
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 875-881
    • Toda, M.1
  • 17
    • 0036603616 scopus 로고    scopus 로고
    • Altered proliferation and differentiation of human epidermis in cases of skin fibrosis after radiotherapy
    • Sivan, V. et al. Altered proliferation and differentiation of human epidermis in cases of skin fibrosis after radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 53, 385-393 (2002).
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.53 , pp. 385-393
    • Sivan, V.1
  • 18
    • 36048989909 scopus 로고    scopus 로고
    • Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice
    • Aberg, K. M. et al. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J. Clin. Invest. 117, 3339-3349 (2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 3339-3349
    • Aberg, K.M.1
  • 20
    • 58849106652 scopus 로고    scopus 로고
    • A tense situation: Forcing tumour progression
    • Butcher, D. T., Alliston, T. & Weaver, V. M. A tense situation: forcing tumour progression. Nat. Rev. Cancer 9, 108-122 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 108-122
    • Butcher, D.T.1    Alliston, T.2    Weaver, V.M.3
  • 21
    • 84902545062 scopus 로고    scopus 로고
    • The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function
    • Achterberg, V. F. et al. The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function. J. Invest. Dermatol. 134, 1862-1872 (2014).
    • (2014) J. Invest. Dermatol. , vol.134 , pp. 1862-1872
    • Achterberg, V.F.1
  • 22
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • Mitra, S. K. & Schlaepfer, D. D. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol. 18, 516-523 (2006).
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 23
    • 84855555498 scopus 로고    scopus 로고
    • Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling
    • Wong, V. W. et al. Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling. Nat. Med. 18, 148-152 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 148-152
    • Wong, V.W.1
  • 24
    • 0027967292 scopus 로고
    • A transmembraneanchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK
    • Chan, P. Y., Kanner, S. B., Whitney, G. & Aruffo, A. A transmembraneanchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK. J. Biol. Chem. 269, 20567-20574 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 20567-20574
    • Chan, P.Y.1    Kanner, S.B.2    Whitney, G.3    Aruffo, A.4
  • 25
    • 79958284636 scopus 로고    scopus 로고
    • Role of YAP/TAZ in mechanotransduction
    • Dupont, S. et al. Role of YAP/TAZ in mechanotransduction. Nature 474, 179-183 (2011).
    • (2011) Nature , vol.474 , pp. 179-183
    • Dupont, S.1
  • 26
    • 84883059455 scopus 로고    scopus 로고
    • Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
    • Swift, J. et al. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 341, 1240104 (2013).
    • (2013) Science , vol.341 , pp. 1240104
    • Swift, J.1
  • 27
    • 0019206908 scopus 로고
    • Connective tissue nevi of the skin. Clinical, genetic, and histopathologic classification of hamartomas of the collagen, elastin, and proteoglycan type
    • Uitto, J., Santa Cruz, D. J. & Eisen, A. Z. Connective tissue nevi of the skin. Clinical, genetic, and histopathologic classification of hamartomas of the collagen, elastin, and proteoglycan type. J. Am. Acad. Dermatol. 3, 441-461 (1980).
    • (1980) J. Am. Acad. Dermatol. , vol.3 , pp. 441-461
    • Uitto, J.1    Santa Cruz, D.J.2    Eisen, A.Z.3
  • 30
    • 84874227659 scopus 로고    scopus 로고
    • Latent TGF-beta binding protein 4 promotes elastic fiber assembly by interacting with Fibulin-5
    • Noda, K. et al. Latent TGF-beta binding protein 4 promotes elastic fiber assembly by interacting with Fibulin-5. Proc. Natl Acad. Sci. USA 110, 2852-2857 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 2852-2857
    • Noda, K.1
  • 31
    • 72849135317 scopus 로고    scopus 로고
    • Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice
    • Heydemann, A. et al. Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J. Clin. Invest. 119, 3703-3712 (2009).
    • (2009) J. Clin. Invest. , vol.119 , pp. 3703-3712
    • Heydemann, A.1
  • 32
    • 77952974791 scopus 로고    scopus 로고
    • Mutations in fibrillin-1 cause congenital scleroderma: Stiff skin syndrome
    • Loeys, B. L. et al. Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome. Sci. Transl. Med. 2, 23ra20 (2010).
    • (2010) Sci. Transl. Med. , vol.2 , pp. 23ra20
    • Loeys, B.L.1
  • 33
    • 84887408112 scopus 로고    scopus 로고
    • Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma
    • Gerber, E. E. et al. Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma. Nature 503, 126-130 (2013).
    • (2013) Nature , vol.503 , pp. 126-130
    • Gerber, E.E.1
  • 34
    • 71549123258 scopus 로고    scopus 로고
    • Prostaglandin F(2alpha) receptor signaling facilitates bleomycininduced pulmonary fibrosis independently of transforming growth factor-beta
    • Oga, T. et al. Prostaglandin F(2alpha) receptor signaling facilitates bleomycininduced pulmonary fibrosis independently of transforming growth factor-beta. Nat. Med. 15, 1426-1430 (2009).
    • (2009) Nat. Med. , vol.15 , pp. 1426-1430
    • Oga, T.1
  • 35
    • 0027980429 scopus 로고
    • Intravenous dexamethasone pulse therapy in diffuse systemic sclerosis. A randomized placebo-controlled study
    • Sharada, B. et al. Intravenous dexamethasone pulse therapy in diffuse systemic sclerosis. A randomized placebo-controlled study. Rheumatol. Int. 14, 91-94 (1994).
    • (1994) Rheumatol. Int. , vol.14 , pp. 91-94
    • Sharada, B.1
  • 36
    • 4344662447 scopus 로고    scopus 로고
    • Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
    • Kajita, M., McClinic, K. N. & Wade, P. A. Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Mol. Cell. Biol. 24, 7559-7566 (2004).
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7559-7566
    • Kajita, M.1    McClinic, K.N.2    Wade, P.A.3
  • 37
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • Kurrey, N. K. et al. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 27, 2059-2068 (2009).
    • (2009) Stem Cells , vol.27 , pp. 2059-2068
    • Kurrey, N.K.1
  • 38
    • 84890117259 scopus 로고    scopus 로고
    • Hypoxia-induced snail expression through transcriptional regulation by HIF-1alpha in pancreatic cancer cells
    • Zhu, G. H., Huang, C., Feng, Z. Z., Lv, X. H. & Qiu, Z. J. Hypoxia-induced snail expression through transcriptional regulation by HIF-1alpha in pancreatic cancer cells. Dig. Dis. Sci. 58, 3503-3515 (2013).
    • (2013) Dig. Dis. Sci. , vol.58 , pp. 3503-3515
    • Zhu, G.H.1    Huang, C.2    Feng, Z.Z.3    Lv, X.H.4    Qiu, Z.J.5
  • 39
    • 84858969597 scopus 로고    scopus 로고
    • Slug is upregulated during wound healing and regulates cellular phenotypes in corneal epithelial cells
    • Aomatsu, K. et al. Slug is upregulated during wound healing and regulates cellular phenotypes in corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 53, 751-756 (2012).
    • (2012) Invest. Ophthalmol. Vis. Sci. , vol.53 , pp. 751-756
    • Aomatsu, K.1
  • 40
    • 14644405666 scopus 로고    scopus 로고
    • A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis
    • Jamora, C. et al. A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 3, e11 (2005).
    • (2005) PLoS Biol. , vol.3 , pp. e11
    • Jamora, C.1
  • 41
    • 0037456847 scopus 로고    scopus 로고
    • Links between signal transduction, transcription and adhesion in epithelial bud development
    • Jamora, C., DasGupta, R., Kocieniewski, P. & Fuchs, E. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422, 317-322 (2003).
    • (2003) Nature , vol.422 , pp. 317-322
    • Jamora, C.1    DasGupta, R.2    Kocieniewski, P.3    Fuchs, E.4
  • 42
    • 67649849871 scopus 로고    scopus 로고
    • Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
    • Shibue, T. & Weinberg, R. A. Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc. Natl Acad. Sci. USA 106, 10290-10295 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 10290-10295
    • Shibue, T.1    Weinberg, R.A.2
  • 43
    • 77953816876 scopus 로고    scopus 로고
    • Preparation of hydrogel substrates with tunable mechanical properties
    • Unit 10 16
    • Tse, J. R. & Engler, A. J. Preparation of hydrogel substrates with tunable mechanical properties. Curr. Protoc. Cell Biol. Chapter 10, Unit 10 16 (2010).
    • (2010) Curr. Protoc. Cell Biol. Chapter , vol.10
    • Tse, J.R.1    Engler, A.J.2
  • 44
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • Pelham, Jr R. J. & Wang, Y. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl Acad. Sci. USA 94, 13661-13665 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13661-13665
    • Pelham, R.J.1    Wang, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.