Flavor misattribution: A novel approach to improving compliance and blinding in food-based clinical interventions

NFS Journal

Volumn 1, Issue , 2015, Pages 24-30

  Bierwirth, Julianne E ^a,d   Oftedal, Katherine N ^b,e   Civille, Gail V ^b   Fahey, Jed W ^a,c  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Sensory Spectrum Inc   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF GEORGIA   (United States)

^e Mondelez International   (France)

Author keywords

Blinding; Broccoli; Masking; Misattribution; Sensory; Taste

Indexed keywords

EID: 84944345674     PISSN: None     EISSN: 23523646     Source Type: Journal    
DOI: 10.1016/j.nfs.2015.07.001     Document Type: Article

References (26)

1. J.W. Fahey, P. Talalay, T.W. Kensler, Notes from the field: "green" chemoprevention as frugal medicine, Cancer Prev. Res. 5 (2) (2012) 179-188.
2. D. Taubert, R. Roesen, C. Lehmann, N. Jung, E. Schomig, Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial, JAMA 298 (1) (2007) 49-60.
3. T. Bunupuradah, S. Wannachai, A. Chuamchaitrakool, J. Intasan, T. Nuchapong, W. Neiss, K. Kramm, C. Pancharoen, D. Burger, J. Ananworanich, Use of taste-masking product, FLAVORx, to assist Thai children to ingest generic antiretrovirals, AIDS Res. Ther. 3 (1) (2006) 30.
4. P. Egner, J.G. Chen, J.B. Wang, Y. Wu, Y. Sun, J.H. Lu, J. Zhu, Y.H. Zhang, Y.S. Chen, M.D. Friesen, L.P. Jacobson, A. Muñoz, D. Ng, G.S. Qian, Y.R. Zhu, T.Y. Chen, N.P. Botting, Q. Zhang, J.W. Fahey, P. Talalay, J.D. Groopman, T.W. Kensler, Bioavailability of sulforaphane fromtwo broccoli sprout beverages: results of a short-termcross-over clinical trial in Qidong, China, Cancer Prev. Res. 4 (3) (2011) 384-395.
5. T.W. Kensler, J.-G. Chen, P.A. Egner, J.W. Fahey, L.P. Jacobson, K.K. Stephenson, X. Ye, J.L. Coady, J.-B. Wang, Y. Wu, Y. Sun, Q.-N. Zhang, B.-C. Zhang, Y.-R. Zhu, G.-S. Qian, S.G. Carmella, S.S. Hecht, L. Benning, S.J. Gange, J.D. Groopman, P. Talalay, Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenalthrene tetraols in a randomized clinical trial in He Zuo Township, Qidong, Peoples Republic of China, Cancer Epidemiol. Biomarkers Prev. 14 (11) (2005) 2605-2613.
6. T.W. Kensle, D. Ng, S.G. Carmella, M. Chen, L.P. Jacobson, A. Muñoz, P.A. Egner, J.G. Chen, G.S. Qian, T.Y. Chen, J.W. Fahey, P. Talalay, J.D. Groopman, J.-M. Yuan, S.S. Hecht, Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China, Carcinogenesis 33 (1) (2012) 101-107.
7. P.A. Egner, J.-G. Chen, A.T. Zarth, D.K. Ng, J.-B. Wang, K.H. Kensler, L.P. Jacobson, A. Muñoz, J.L. Johnson, J.D. Groopman, J.W. Fahey, P. Talalay, J. Zhu, T.-Y. Chen, G.-S. Qian, S.G. Carmella, S.S. Hecht, T.W. Kensler, Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China, Cancer Prev. Res. 7 (8) (2014) 813-823.
8. K. Singh, S.L. Connors, E.A. Macklin, K.D. Smith, J.W. Fahey, P. Talalay, A.W. Zimmerman, Sulforaphane treatment of autism spectrum disorder (ASD), Proc. Natl. Acad. Sci. U. S. A. 111 (43) (2014) 15550-15555.
9. D. Heber, Z. Li, M. Garcia-Lloret, A.M. Wong, T.Y. Lee, G. Thames, M. Krak, Y. Zhang, A. Nel, Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles, Food Funct. 2014 (5) (1975) 35-41.
10. J.J. Alumkal, R. Slottke, J. Schwartzman, G. Cherala, M. Munar, J.N. Graff, T.A. Beer, C.A. Ryan, D.R. Koop, A. Gibbs, L. Gao, J.F. Flamiatos, E. Tucher, R. Kleinschmidt, M. Mori, A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer, Investig. New Drugs (2014), http://dx.doi.org/10.1007/s10637-014-0189-z.
11. M.J. Nagtegaal, J.J. Swen, L.M. Hanff, K.J.M. Schimmel, H.-J. Guchelaar, Pharmacogenetic of taste: turning bitter pills sweet? Pharmacogenomics 15 (1) (2014) 111-119.
12. L. Martin, D. Zarn, A. Hansen, W. Wimser, V. Mazurak, Food products as vehicles for n-3 fatty acid supplementation, Can. J. Diet. Pract. Res. 69 (4) (2008) 203-207.
13. N. Shet, I. Vaidya, Taste masking: a pathfinder for bitter drugs, Int. J. Pharm. Sci. Rev. Res. 18 (2) (Jan-Feb 2013) 1-12 (No 1).
14. T. Luckow, V. Sheehan, G. Fitzgerald, C. Delahunty, Exposure, health information and flavour-masking strategies for improving the sensory quality of probiotic juice, Appetite 47 (3) (2006) 315-323.
15. W.F. Dove, Developing food acceptance research, Science 103 (2668) (1946) 187-190.
16. R.M. Pangborn, Sensory evaluation of food: a look backward and forward, Food Technol. 18 (1964) 1309.
17. M. Meilgaard, T. Carr, G. Civille, Sensory Evaluation Techniques, 4th ed. CRC Press, Boca Raton, FL, 2007.
18. Y.-Y. Ahn, S.E. Ahnert, J.P. Bagrow, A.-L. Barabasi, Flavor network and the principles of food pairing, Sci. Rep. 1 (2011) 196, http://dx.doi.org/10.1038/srep00196.
19. G.V. Civille, K.N. Oftedal, Sensory evaluation techniques-make "good for you" taste "good", Physiol. Behav. 107 (4) (2012) 598-605.
20. J.A. Gottfried, Central mechanisms of odour object perception, Nat. Rev. Neurosci. 11 (8) (2010) 628-641.
21. D.M. Small, B.G. Green, A proposed model of a flavor modality, in:M.M. Murray, M.T. Wallace (Eds.), The Neural Bases of Multisensory Processes, CRC Press, Boca Raton (FL), 2012 (Chapter 36, http://www.ncbi.nlm.nih.gov/books/NBK92876/).
22. H. Lawless, H. Heymann, Sensory Evaluation of Food: Principles and Practices, Springer, Tokyo, 2009.
23. O. Nishimura, Identification of the characteristic odorants in fresh rhizomes of ginger (Zingiber officinale Roscoe) using aroma extract dilution analysis and modified multidimensional gas chromatography-mass spectroscopy, J. Agric. Food Chem. 43 (1996) 2941-2945.
24. J.F. Melleunet, R. Xiong, C.J. Findlay, Multivariate and Probabilistic Analysis of Sensory Science Problems, First ed. Blackwell Publishing, IFT Press, 2007.
25. D.E. Johnson, Applied Multivariate Methods for Data Analysis, Duxbury Press: Brooks/Cole Publishing, 1998.
26. A. Munoz, Relating Consumer Descriptive and Laboratory Data to Better Understand Consumer Responses, ASTM Manual series, MNL 30, 1997.