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Angewandte Chemie - International Edition

Volumn 54, Issue 43, 2015, Pages 12697-12701

Discovery of a single monooxygenase that catalyzes carbamate formation and ring contraction in the biosynthesis of the legonmycins

(13) Huang, Sheng a Tabudravu, Jioji b Elsayed, Somayah S b Travert, Jeanne b Peace, Doe b Tong, Ming Him b Kyeremeh, Kwaku c Kelly, Sharon M d Trembleau, Laurent b Ebel, Rainer b Jaspars, Marcel b Yu, Yi a Deng, Hai b

a WUHAN UNIVERSITY (China)

b UNIVERSITY OF ABERDEEN (United Kingdom)

c UNIVERSITY OF GHANA (Ghana)

d UNIVERSITY OF GLASGOW (United Kingdom)

Author keywords

biosynthesis; legonmycins; multifunctional enzymes; non ribosomal peptide synthetases; pyrrolizidine alkaloids

Indexed keywords

ALKALOIDS; BIOCHEMISTRY; ENZYMES; GENE EXPRESSION; METABOLITES; PEPTIDES;

GENE INACTIVATION; HETEROLOGOUS EXPRESSION; LEGONMYCINS; NATURAL PRODUCTS; PYRROLIZIDINE ALKALOID; RIBOSOMAL PEPTIDES; RING CONTRACTION; SYNTHETASES;

BIOSYNTHESIS;

BIOLOGICAL PRODUCT; CARBAMIC ACID DERIVATIVE; MIXED FUNCTION OXIDASE; PYRROLIZIDINE ALKALOID;

BACTERIAL GENE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MICROBIOLOGY; MULTIGENE FAMILY; STREPTOMYCES;

BIOLOGICAL PRODUCTS; CARBAMATES; GENES, BACTERIAL; MIXED FUNCTION OXYGENASES; MULTIGENE FAMILY; PYRROLIZIDINE ALKALOIDS; SOIL MICROBIOLOGY; STREPTOMYCES;

EID: 84944279359 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201502902 Document Type: Article

Times cited : (42)

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