Endothelial miR-17~92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 41, 2015, Pages 12812-12817

  Landskroner Eiger, Shira ^a   Qiu, Cong ^a   Perrotta, Paola ^a   Siragusa, Mauro ^a   Lee, Monica Y ^a   Ulrich, Victoria ^a   Luciano, Amelia K ^a   Zhuang, Zhen W ^a   Corti, Federico ^a   Simons, Michael ^a   Montgomery, Rusty L ^b   Wu, Dianqing ^a   Yu, Jun ^a   Sessa, William C ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MiRagen Therapeutics   (United States)

Author keywords

Arteriogenesis; Endothelium; MicroRNA; Vascular

Indexed keywords

FRIZZLED PROTEIN; FZD4 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MICRORNA; MICRORNA 17; MICRORNA 17A; MICRORNA 18A; MICRORNA 19; MICRORNA 19A; UNCLASSIFIED DRUG; WNT PROTEIN; FZD4 PROTEIN, MOUSE; LRP6 PROTEIN, MOUSE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY BLOOD FLOW; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DELETION; GENE REPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIMB BLOOD FLOW; LIMB ISCHEMIA; LUCIFERASE ASSAY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; GENETICS; ISCHEMIA; KNOCKOUT MOUSE; METABOLISM; MULTIGENE FAMILY; PATHOLOGY; PHYSIOLOGY; WNT SIGNALING PATHWAY;

ANIMALS; FRIZZLED RECEPTORS; ISCHEMIA; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MICE; MICE, KNOCKOUT; MICRORNAS; MULTIGENE FAMILY; NEOVASCULARIZATION, PHYSIOLOGIC; WNT SIGNALING PATHWAY;

EID: 84944236555     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1507094112     Document Type: Article

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