Protective effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced acute kidney injury in a rat model of sepsis

International Urology and Nephrology

Volumn 47, Issue 10, 2015, Pages 1745-1752

  Liu, Lin ^a   Song, Yijin ^b   Zhao, Ming ^a   Yi, Zhuwen ^b   Zeng, Qiyi ^c  

^a THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Acute kidney injury; Edaravone; LPS; Mitochondrial fragmentation; Sepsis

Indexed keywords

CASPASE 3; CATALASE; CREATININE; CYTOCHROME C; GLUTATHIONE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MALONALDEHYDE; NORPHENAZONE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; PHENAZONE; PHENYLMETHYLPYRAZOLONE; SCAVENGER;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; DRUG EFFECT; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; KIDNEY CORTEX; KIDNEY PARENCHYMA; KIDNEY TUBULE CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; SEPSIS; UREA NITROGEN BLOOD LEVEL; ACUTE KIDNEY INJURY; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; CELL CULTURE; CHEMICALLY INDUCED; COMPLICATION; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; KIDNEY TUBULE; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; PATHOLOGY; WISTAR RAT;

ACUTE KIDNEY INJURY; ANIMALS; ANTIPYRINE; APOPTOSIS; BLOOD UREA NITROGEN; CATALASE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; GLUTATHIONE; INTERLEUKIN-6; KIDNEY TUBULES; LIPOPOLYSACCHARIDES; MALE; MALONDIALDEHYDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; OXIDATIVE STRESS; RATS; RATS, WISTAR; SEPSIS; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84944164795     PISSN: 03011623     EISSN: 15732584     Source Type: Journal    
DOI: 10.1007/s11255-015-1070-5     Document Type: Article

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