Systematic analysis of gene expression pattern in has-miR-197 over-expressed human uterine leiomyoma cells

Biomedicine and Pharmacotherapy

Volumn 75, Issue , 2015, Pages 226-233

  Ling, Jing ^b   Wu, Xiaoli ^c   Fu, Ziyi ^a   Tan, Jie ^b   Xu, Qing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Department of Obstetrics and Gynecology Affiliated Jiangyin Hospital of South East University   (China)

^c WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Gene microarray; Human uterine leiomyoma cells; Mechanism; MiR 197

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE AMINOPHOSPHOLIPID TRANSPORTER CLASS I TYPE 8A MEMBER 2; CALCIUM CHANNEL; CALCIUM CHANNEL VOLTAGE DEPENDENT GAMMA SUBUNIT 7; CHROMOSOME X OPEN READING FRAME 51A; COMPLEMENTARY DNA; CYTOKINE RECEPTOR; FIBULIN; FIBULIN 2; G PROTEIN COUPLED RECEPTOR; GLYCOSPHINGOLIPID; HEMOGLOBIN A2; HOMEOBOX PROTEIN HOX D12; HOMEODOMAIN PROTEIN; JANUS KINASE; MICRORNA; MICRORNA 197; PROTEIN; STAT PROTEIN; THIOSULFATE SULFURTRANSFERASE RHODANESE LIKE DOMAIN CONTAINING 1; TOLL LIKE RECEPTOR; TRIPARTITE MOTIF PROTEIN 75; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; MIRN197 MICRORNA, HUMAN;

ADULT; ARTICLE; BIOSYNTHESIS; C10ORF35 GENE; CACNG7 GENE; CANCER GROWTH; CDRT7 GENE; CELL COMMUNICATION; CELL COMPONENT; CELL DENSITY; CELL MEMBRANE; CELL STIMULATION; CHOLINERGIC SYNAPSE; CONTROLLED STUDY; DOWN REGULATION; DRT7 GENE; ENZYME ACTIVITY; FDFR2 GENE; FEMALE; FLJ37956 GENE; GENE; GENE EXPRESSION; GENE ONTOLOGY; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LENTIVIRUS INFECTION; LOC10013427 GENE; LOC100134279 GENE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; OR5IL GENE; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR BINDING; SFMBT2 GENE; SIGNAL TRANSDUCTION; SLC549 GENE; UPREGULATION; UTERUS MYOMA; VPREB1 GENE; BIOLOGY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENE VECTOR; GENETICS; LEIOMYOMA; LENTIVIRINAE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROCEDURES; TUMOR CELL CULTURE; UTERUS CANCER;

ADULT; COMPUTATIONAL BIOLOGY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; GENETIC VECTORS; HUMANS; LEIOMYOMA; LENTIVIRUS; MICRORNAS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION; UTERINE NEOPLASMS;

EID: 84944155010     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2015.07.039     Document Type: Article

References (32)

1. Whirledge S., Dixon D., Cidlowski J.A. Glucocorticoids regulate gene expression and repress cellular proliferation human uterine leiomyoma cells. Horm. Cancer 2012, 3:79-92.
2. Feng Y., Zhao X., Zhou C., Yang L., Liu Y., Bian C., Gou J., Lin X., Wang Z., Zhao X. The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM). Gene 2013, 529(2):296-299.
3. Kiechle-Schwarz M., Sreekantaiah C., Berger C.S., et al. Nonrandom cytogenetic changes in leiomyomas of the female genitourinary tract. Areport of 35 cases. Cancer Genet. Cytogenet. 1991, 53:125-136.
4. Rein M.S., Friedman A.J., Barbieri R.L., Pavelka K., Fletcher J.A., Morton C.C. Cytogenetic abnormalities in uterine leiomyomata. Obstet. Gynecol. 1991, 77:923-926.
5. Meloni A.M., Surti U., Contento A.M., Davare J., Sandberg A.A. Uterine leiomyomas: cytogenetic and histologic profile. Obstet. Gynecol. 1992, 80:209-217.
6. Walker C.L., Stewart E.A. Uterine fibroids: the elephant in the room. Science 2005, 308:1589-1592.
7. Cha P.C., Takahashi A., Hosono N., et al. Agenome-wide association study identifies three loci associated with susceptibility to uterine fibroids. Nat. Genet. 2011, 43:447-450.
8. Ligon A.H., Scott I.C., Takahara K., Greenspan D.S., Morton C.C. PCOLCE deletion and expression analyses in uterine leiomyomata. Cancer Genet. Cytogenet. 2002, 137:133-137.
9. Ptacek T., Song C., Walker C.L., Sell S.M. Physical mapping of distinct 7q22 deletions in uterine leiomyoma and analysis of a recently annotated 7q22 candidate gene. Cancer Genet. Cytogenet. 2007, 174:116-120.
10. Velagaleti G.V., Tonk V.S., Hakim N.M., et al. Fusion of HMGA2 to COG5 in uterine leiomyoma. Cancer Genet. Cytogenet. 2011, 202:11-16.
11. Mäkinen N., Mehine M., Tolvanen J., et al. MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas. Science 2011, 334:252-255.
12. Nezhad M.H., Drieschner N., Helms S., et al. 6p21 rearrangements in uterine leiomyomas targeting HMGA1. Cancer Genet. Cytogenet. 2010, 203:247-252.
13. Sandberg A.A. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: leiomyoma. Cancer Genet. Cytogenet. 2005, 158(1):1-26.
14. El-Gharib M.N., Elsobky E.S. Cytogenetic aberrations and the development of uterine leiomyomata. J. Obstet. Gynaecol. Res. 2010, 36:101-107.
15. Marsh E.E., Lin Z., Yin P., Milad M., Chakravarti D., Bulun S.E. Differential expression of microRNA species in human uterine leiomyoma versus normal myometrium. Fertil. Steril. 2008, 89:1771-1776.
16. Navarro A., Yin P., Monsivais D., et al. Genome-wide DNA methylation indicates silencing of tumor suppressor genes in uterine leiomyoma. PloS One 2012, 7:e33284.
17. Wei L.H., Torng P.L., Hsiao S.M., Jeng Y.M., Chen M.W., Chen C.A. Histone deacetylase 6 regulates estrogen receptor in uterine leiomyoma. Reprod. Sci. 2011, 18:755-762.
18. Pan Q., Luo X., Chegini N. Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids. J. Cell. Mol. Med. 2008, 12(1):227-240.
19. Arola-Arnal A., Bladé C. Proanthocyanidins modulate microRNA expression in human HepG2 cells. PLoS One 2011, 6(10):e25982.
20. Zheng D., Haddadin S., Wang Y., et al. Plasma microRNAs as novel biomarkers for early detection of lung cancer. Int. J. Clin. Exp. Pathol. 2011, 4(6):575-586.
21. Li X., Zhang Y., Zhang H., et al. miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3. Mol. Cancer Res. 2011, 9(7):824-833.
22. Lehmann U., Streichert T., Otto B., et al. Identification of differentially expressed microRNAs in human male breast cancer. BMC Cancer 2010, 23(10):109.
23. Chen L., Li C., Peng Z., et al. miR-197 expression in peripheral blood mononuclear cells from hepatitis B virus-infected patients. Gut Liver 2013, 7(3):335-342.
24. Kannan M., Atreya C. Differential profiling of human red blood cells during storage for 52 selected microRNAs. Transfusion 2010, 50(7):1581-1588.
25. Wang T., Zhang X., Obijuru L., et al. A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. Genes Chromosomes Cancer 2007, 46:336-347.
26. Strawn E.Y., Novy M.J., Burry K.A., et al. Insulin-like growth factor I promotes leiomyoma cell growth in vitro. Am. J. Obstet. Gynecol. 2005, 172(6):1837-1843.
27. Pan Q., Luo X., Chegini N. Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids. J. Cell. Mol. Med. 2008, 12(1):227-240.
28. Yun H.J., Kim S.Y., Kwon Y.Y., et al. Janus-activated kinases and signal transducer and activator of transcription control tumor growth response to camptothecin in human colon cancer cells. Cancer Biol. Ther. 2010, 10:354-361.
29. Myers E.R., Barber M.D., Gustilo-Ashby T., Couchman G., Matchar D.B., McCrory D.C. Management of uterine leiomyomata: what do we really know?. Obstet. Gynecol. 2002, 100:8-17.
30. Wang T., Zhang X., Obijuru L., Laser J., Aris V., Lee P., Mittal K., Soteropoulos P., Wei J.J. A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. Genes Chromosomes Cancer 2007, 46:336-347.
31. Zavadil J., Ye H., Liu Z., et al. Profiling and functional analyses o microRNAs and their target gene products in human uterine leiomyomas. PLoS One 2010, 2362.
32. Khan K.N., Kitajima M., Hiraki K., et al. Toll-like receptors in innate immunity: role of bacterial endotoxin and toll-like receptor 4 in endometrium and endometriosis. Gynecol. Obstet. Invest. 2009, 68:40-52.