Genome-wide DNA methylation indicates silencing of tumor suppressor genes in uterine leiomyoma

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Navarro, Antonia ^a   Yin, Ping ^a   Monsivais, Diana ^a   Lin, Simon M ^a   Du, Pan ^a   Wei, Jian Jun ^a   Bulun, Serdar E ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 19; DELETED IN LUNG AND ESOPHAGEAL CANCER 1; DNA; DNA METHYLTRANSFERASE INHIBITOR; KRUPPEL LIKE FACTOR 11; MESSENGER RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; PRIMER DNA;

ADULT; AFRICAN AMERICAN; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DLEC1 GENE; DNA METHYLATION; FEMALE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; INCUBATION TIME; KLF11 GENE; KRT19 GENE; MYOMETRIUM; PROMOTER REGION; PROTEIN METHYLATION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SMOOTH MUSCLE FIBER; TUMOR SUPPRESSOR GENE; UTERUS MYOMA; WESTERN BLOTTING; ANALYSIS OF VARIANCE; COMPARATIVE STUDY; DNA SEQUENCE; GENETICS; LEIOMYOMA; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; UNITED STATES; UTERUS CANCER;

ADULT; AFRICAN AMERICANS; ANALYSIS OF VARIANCE; BASE SEQUENCE; BLOTTING, WESTERN; DNA METHYLATION; DNA PRIMERS; FEMALE; GENE EXPRESSION PROFILING; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HUMANS; LEIOMYOMA; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MYOMETRIUM; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; UNITED STATES; UTERINE NEOPLASMS;

EID: 84863281534     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033284     Document Type: Article

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