메뉴 건너뛰기




Volumn 112, Issue 41, 2015, Pages 12681-12686

Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system

Author keywords

Apoptosis; cAMP; Glucocorticoids; Lymphoma; PKA

Indexed keywords

APOPTOSIS INDUCING FACTOR; BIM PROTEIN; CASPASE 3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; CYCLIC AMP DERIVATIVE; DEXAMETHASONE; FORSKOLIN; MESSENGER RNA; PROTEIN KINASE C ALPHA; SORBITOL; APOPTOSIS REGULATORY PROTEIN; BCL2L11 PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN;

EID: 84944128511     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516057112     Document Type: Article
Times cited : (11)

References (51)
  • 1
    • 4644263340 scopus 로고    scopus 로고
    • Effects of glucocorticoids on gene transcription
    • Hayashi R, Wada H, Ito K, Adcock IM (2004) Effects of glucocorticoids on gene transcription. Eur J Pharmacol 500(1-3):51-62.
    • (2004) Eur J Pharmacol , vol.500 , Issue.1-3 , pp. 51-62
    • Hayashi, R.1    Wada, H.2    Ito, K.3    Adcock, I.M.4
  • 2
    • 33846467093 scopus 로고    scopus 로고
    • Regulation of differential pro- and antiapoptotic signaling by glucocorticoids
    • Herr I, Gassler N, Friess H, Büchler MW (2007) Regulation of differential pro- and antiapoptotic signaling by glucocorticoids. Apoptosis 12(2):271-291.
    • (2007) Apoptosis , vol.12 , Issue.2 , pp. 271-291
    • Herr, I.1    Gassler, N.2    Friess, H.3    Büchler, M.W.4
  • 3
    • 80054986457 scopus 로고    scopus 로고
    • The effects of glucocorticoids on adipose tissue lipid metabolism
    • Peckett AJ, Wright DC, Riddell MC (2011) The effects of glucocorticoids on adipose tissue lipid metabolism. Metabolism 60(11):1500-1510.
    • (2011) Metabolism , vol.60 , Issue.11 , pp. 1500-1510
    • Peckett, A.J.1    Wright, D.C.2    Riddell, M.C.3
  • 4
    • 0035413602 scopus 로고    scopus 로고
    • Physiological substrates of cAMP-dependent protein kinase
    • Shabb JB (2001) Physiological substrates of cAMP-dependent protein kinase. Chem Rev 101(8):2381-2411.
    • (2001) Chem Rev , vol.101 , Issue.8 , pp. 2381-2411
    • Shabb, J.B.1
  • 5
    • 33744998954 scopus 로고    scopus 로고
    • Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitinmediated degradation of cyclin D1
    • Sundberg M, Savola S, Hienola A, Korhonen L, Lindholm D (2006) Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitinmediated degradation of cyclin D1. J Neurosci 26(20):5402-5410.
    • (2006) J Neurosci , vol.26 , Issue.20 , pp. 5402-5410
    • Sundberg, M.1    Savola, S.2    Hienola, A.3    Korhonen, L.4    Lindholm, D.5
  • 6
    • 84937540139 scopus 로고    scopus 로고
    • Cyclic AMP/PKA-promoted apoptosis: Insights from studies of S49 lymphoma cells
    • Insel PA, Wilderman A, Zhang L, Keshwani MM, Zambon AC (2014) Cyclic AMP/PKA-promoted apoptosis: Insights from studies of S49 lymphoma cells. Horm Metab Res 46(12):854-862.
    • (2014) Horm Metab Res , vol.46 , Issue.12 , pp. 854-862
    • Insel, P.A.1    Wilderman, A.2    Zhang, L.3    Keshwani, M.M.4    Zambon, A.C.5
  • 7
    • 84855350974 scopus 로고    scopus 로고
    • Cyclic AMP is both a proapoptotic and anti-apoptotic second messenger
    • Insel PA, Zhang L, Murray F, Yokouchi H, Zambon AC (2012) Cyclic AMP is both a proapoptotic and anti-apoptotic second messenger. Acta Physiol (Oxf) 204(2):277-287.
    • (2012) Acta Physiol (Oxf) , vol.204 , Issue.2 , pp. 277-287
    • Insel, P.A.1    Zhang, L.2    Murray, F.3    Yokouchi, H.4    Zambon, A.C.5
  • 8
    • 84866729606 scopus 로고    scopus 로고
    • Assembly of allosteric macromolecular switches: Lessons from PKA
    • Taylor SS, Ilouz R, Zhang P, Kornev AP (2012) Assembly of allosteric macromolecular switches: Lessons from PKA. Nat Rev Mol Cell Biol 13(10):646-658.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.10 , pp. 646-658
    • Taylor, S.S.1    Ilouz, R.2    Zhang, P.3    Kornev, A.P.4
  • 9
    • 84885441920 scopus 로고    scopus 로고
    • Local cAMP signaling in disease at a glance
    • Gold MG, Gonen T, Scott JD (2013) Local cAMP signaling in disease at a glance. J Cell Sci 126(Pt 20):4537-4543.
    • (2013) J Cell Sci , vol.126 , pp. 4537-4543
    • Gold, M.G.1    Gonen, T.2    Scott, J.D.3
  • 10
    • 80053450655 scopus 로고    scopus 로고
    • Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a
    • Yin Z, Pringle DR, Jones GN, Kelly KM, Kirschner LS (2011) Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a. Mol Endocrinol 25(10):1786-1793.
    • (2011) Mol Endocrinol , vol.25 , Issue.10 , pp. 1786-1793
    • Yin, Z.1    Pringle, D.R.2    Jones, G.N.3    Kelly, K.M.4    Kirschner, L.S.5
  • 11
    • 0016816003 scopus 로고
    • Mechanism of lymphoma cell death induced by cyclic AMP
    • Coffino P, Bourne HR, Tomkins GM (1975) Mechanism of lymphoma cell death induced by cyclic AMP. Am J Pathol 81(1):199-204.
    • (1975) Am J Pathol , vol.81 , Issue.1 , pp. 199-204
    • Coffino, P.1    Bourne, H.R.2    Tomkins, G.M.3
  • 12
    • 0016772772 scopus 로고
    • Cyclic AMP-dependent protein kinase: Pivotal role in regulation of enzyme induction and growth
    • Insel PA, Bourne HR, Coffino P, Tomkins GM (1975) Cyclic AMP-dependent protein kinase: Pivotal role in regulation of enzyme induction and growth. Science 190(4217):896-898.
    • (1975) Science , vol.190 , Issue.4217 , pp. 896-898
    • Insel, P.A.1    Bourne, H.R.2    Coffino, P.3    Tomkins, G.M.4
  • 13
    • 0017716885 scopus 로고
    • Reconstitution of catecholamine-sensitive adenylate cyclase activity: Interactions of solubilized components with receptor-replete membranes
    • Ross EM, Gilman AG (1977) Reconstitution of catecholamine-sensitive adenylate cyclase activity: Interactions of solubilized components with receptor-replete membranes. Proc Natl Acad Sci USA 74(9):3715-3719.
    • (1977) Proc Natl Acad Sci USA , vol.74 , Issue.9 , pp. 3715-3719
    • Ross, E.M.1    Gilman, A.G.2
  • 14
    • 20844453092 scopus 로고    scopus 로고
    • Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A
    • Zambon AC, et al. (2005) Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A. Proc Natl Acad Sci USA 102(24):8561-8566.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.24 , pp. 8561-8566
    • Zambon, A.C.1
  • 15
    • 2442682766 scopus 로고    scopus 로고
    • The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells
    • Zhang L, Insel PA (2004) The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells. J Biol Chem 279(20):20858-20865.
    • (2004) J Biol Chem , vol.279 , Issue.20 , pp. 20858-20865
    • Zhang, L.1    Insel, P.A.2
  • 16
    • 0016620163 scopus 로고
    • A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells
    • Hochman J, Insel PA, Bourne HR, Coffino P, Tomkins GM (1975) A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells. Proc Natl Acad Sci USA 72(12):5051-5055.
    • (1975) Proc Natl Acad Sci USA , vol.72 , Issue.12 , pp. 5051-5055
    • Hochman, J.1    Insel, P.A.2    Bourne, H.R.3    Coffino, P.4    Tomkins, G.M.5
  • 17
    • 0029891277 scopus 로고    scopus 로고
    • Pathways for degradation of the catalytic subunit of cAMP-dependent protein kinase differ in wild-type and kinase-negative S49 mouse lymphoma cells
    • Lee SL, Steinberg RA (1996) Pathways for degradation of the catalytic subunit of cAMP-dependent protein kinase differ in wild-type and kinase-negative S49 mouse lymphoma cells. J Biol Chem 271(28):16553-16558.
    • (1996) J Biol Chem , vol.271 , Issue.28 , pp. 16553-16558
    • Lee, S.L.1    Steinberg, R.A.2
  • 18
    • 0025255867 scopus 로고
    • The S49 Kin-cell line transcribes and translates a functional mRNA coding for the catalytic subunit of cAMP-dependent protein kinase
    • Orellana SA, McKnight GS (1990) The S49 Kin-cell line transcribes and translates a functional mRNA coding for the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 265(6):3048-3053.
    • (1990) J Biol Chem , vol.265 , Issue.6 , pp. 3048-3053
    • Orellana, S.A.1    McKnight, G.S.2
  • 19
    • 0026098765 scopus 로고
    • A kinase-negative mutant of S49 mouse lymphoma cells is defective in posttranslational maturation of catalytic subunit of cyclic AMP-dependent protein kinase
    • Steinberg RA (1991) A kinase-negative mutant of S49 mouse lymphoma cells is defective in posttranslational maturation of catalytic subunit of cyclic AMP-dependent protein kinase. Mol Cell Biol 11(2):705-712.
    • (1991) Mol Cell Biol , vol.11 , Issue.2 , pp. 705-712
    • Steinberg, R.A.1
  • 20
    • 84861205906 scopus 로고    scopus 로고
    • Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase
    • Keshwani MM, et al. (2012) Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 109(20):E1221-E1229.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.20 , pp. E1221-E1229
    • Keshwani, M.M.1
  • 21
    • 52049119312 scopus 로고    scopus 로고
    • Protein kinase A (PKA) isoform RIIbeta mediates the synergistic killing effect of cAMP and glucocorticoid in acute lymphoblastic leukemia cells
    • Ji Z, Mei FC, Miller AL, Thompson EB, Cheng X (2008) Protein kinase A (PKA) isoform RIIbeta mediates the synergistic killing effect of cAMP and glucocorticoid in acute lymphoblastic leukemia cells. J Biol Chem 283(32):21920-21925.
    • (2008) J Biol Chem , vol.283 , Issue.32 , pp. 21920-21925
    • Ji, Z.1    Mei, F.C.2    Miller, A.L.3    Thompson, E.B.4    Cheng, X.5
  • 22
    • 84869780798 scopus 로고    scopus 로고
    • RCAN1 is an important mediator of glucocorticoid-induced apoptosis in human leukemic cells
    • Nagao K, Iwai Y, Miyashita T (2012) RCAN1 is an important mediator of glucocorticoid-induced apoptosis in human leukemic cells. PLoS One 7(11):e49926.
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e49926
    • Nagao, K.1    Iwai, Y.2    Miyashita, T.3
  • 23
    • 0028108027 scopus 로고
    • Threonine-497 is a critical site for permissive activation of protein kinase C alpha
    • Cazaubon S, Bornancin F, Parker PJ (1994) Threonine-497 is a critical site for permissive activation of protein kinase C alpha. Biochem J 301(Pt 2):443-448.
    • (1994) Biochem J , vol.301 , pp. 443-448
    • Cazaubon, S.1    Bornancin, F.2    Parker, P.J.3
  • 24
    • 0028292769 scopus 로고
    • Intrapeptide regulation of protein kinase C
    • Orr JW, Newton AC (1994) Intrapeptide regulation of protein kinase C. J Biol Chem 269(11):8383-8387.
    • (1994) J Biol Chem , vol.269 , Issue.11 , pp. 8383-8387
    • Orr, J.W.1    Newton, A.C.2
  • 25
    • 0031888577 scopus 로고    scopus 로고
    • Physiological phosphorylation of protein kinase A at Thr-197 is by a protein kinase A kinase
    • Cauthron RD, Carter KB, Liauw S, Steinberg RA (1998) Physiological phosphorylation of protein kinase A at Thr-197 is by a protein kinase A kinase. Mol Cell Biol 18(3):1416-1423.
    • (1998) Mol Cell Biol , vol.18 , Issue.3 , pp. 1416-1423
    • Cauthron, R.D.1    Carter, K.B.2    Liauw, S.3    Steinberg, R.A.4
  • 26
    • 33745821637 scopus 로고    scopus 로고
    • Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
    • Nirula A, Ho M, Phee H, Roose J, Weiss A (2006) Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4. J Exp Med 203(7):1733-1744.
    • (2006) J Exp Med , vol.203 , Issue.7 , pp. 1733-1744
    • Nirula, A.1    Ho, M.2    Phee, H.3    Roose, J.4    Weiss, A.5
  • 27
    • 0037200043 scopus 로고    scopus 로고
    • The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C
    • Gao T, Newton AC (2002) The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C. J Biol Chem 277(35):31585-31592.
    • (2002) J Biol Chem , vol.277 , Issue.35 , pp. 31585-31592
    • Gao, T.1    Newton, A.C.2
  • 28
    • 0032514734 scopus 로고    scopus 로고
    • Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene
    • De Cesare D, Jacquot S, Hanauer A, Sassone-Corsi P (1998) Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. Proc Natl Acad Sci USA 95(21):12202-12207.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.21 , pp. 12202-12207
    • De Cesare, D.1    Jacquot, S.2    Hanauer, A.3    Sassone-Corsi, P.4
  • 29
    • 0141922981 scopus 로고    scopus 로고
    • TORCs: Transducers of regulated CREB activity
    • Conkright MD, et al. (2003) TORCs: Transducers of regulated CREB activity. Mol Cell 12(2):413-423.
    • (2003) Mol Cell , vol.12 , Issue.2 , pp. 413-423
    • Conkright, M.D.1
  • 30
    • 42949157936 scopus 로고    scopus 로고
    • Gene expression signatures of cAMP/protein kinase A (PKA) - Promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells
    • Zhang L, et al. (2008) Gene expression signatures of cAMP/protein kinase A (PKA) - promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells. J Biol Chem 283(7):4304-4313.
    • (2008) J Biol Chem , vol.283 , Issue.7 , pp. 4304-4313
    • Zhang, L.1
  • 31
    • 0025940335 scopus 로고
    • The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase
    • Boshart M, Weih F, Nichols M, Schütz G (1991) The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase. Cell 66(5):849-859.
    • (1991) Cell , vol.66 , Issue.5 , pp. 849-859
    • Boshart, M.1    Weih, F.2    Nichols, M.3    Schütz, G.4
  • 32
    • 79953296182 scopus 로고    scopus 로고
    • Control of PKA stability and signalling by the RING ligase praja2
    • Lignitto L, et al. (2011) Control of PKA stability and signalling by the RING ligase praja2. Nat Cell Biol 13(4):412-422.
    • (2011) Nat Cell Biol , vol.13 , Issue.4 , pp. 412-422
    • Lignitto, L.1
  • 33
    • 80052992261 scopus 로고    scopus 로고
    • Increased expression of the proapoptotic protein BIM, a mechanism for cAMP/protein kinase A (PKA)-induced apoptosis of immature T cells
    • Zambon AC, Wilderman A, Ho A, Insel PA (2011) Increased expression of the proapoptotic protein BIM, a mechanism for cAMP/protein kinase A (PKA)-induced apoptosis of immature T cells. J Biol Chem 286(38):33260-33267.
    • (2011) J Biol Chem , vol.286 , Issue.38 , pp. 33260-33267
    • Zambon, A.C.1    Wilderman, A.2    Ho, A.3    Insel, P.A.4
  • 34
    • 84889087067 scopus 로고    scopus 로고
    • Role of p53 in cAMP/PKA pathway mediated apoptosis
    • Rahimi A, et al. (2013) Role of p53 in cAMP/PKA pathway mediated apoptosis. Apoptosis 18(12):1492-1499.
    • (2013) Apoptosis , vol.18 , Issue.12 , pp. 1492-1499
    • Rahimi, A.1
  • 35
    • 78650886200 scopus 로고    scopus 로고
    • Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim
    • Moujalled D, et al. (2011) Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim. EMBO Rep 12(1):77-83.
    • (2011) EMBO Rep , vol.12 , Issue.1 , pp. 77-83
    • Moujalled, D.1
  • 36
    • 0035967169 scopus 로고    scopus 로고
    • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
    • Joza N, et al. (2001) Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410(6828):549-554.
    • (2001) Nature , vol.410 , Issue.6828 , pp. 549-554
    • Joza, N.1
  • 37
    • 0034617449 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
    • Daugas E, et al. (2000) Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett 476(3):118-123.
    • (2000) FEBS Lett , vol.476 , Issue.3 , pp. 118-123
    • Daugas, E.1
  • 38
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: The next generation. Cell 144(5):646-674.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 39
    • 0016737681 scopus 로고
    • Somatic genetic analysis of cyclic AMP action: Characterization of unresponsive mutants
    • Bourne HR, Coffino P, Tomkins GM (1975) Somatic genetic analysis of cyclic AMP action: Characterization of unresponsive mutants. J Cell Physiol 85(3):611-620.
    • (1975) J Cell Physiol , vol.85 , Issue.3 , pp. 611-620
    • Bourne, H.R.1    Coffino, P.2    Tomkins, G.M.3
  • 40
    • 84901433308 scopus 로고    scopus 로고
    • APC (Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction
    • Wan L, et al. (2014) APC (Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction. Dev Cell 29(4):377-391.
    • (2014) Dev Cell , vol.29 , Issue.4 , pp. 377-391
    • Wan, L.1
  • 41
    • 84873155268 scopus 로고    scopus 로고
    • A kinase interacting protein (AKIP1) is a key regulator of cardiac stress
    • Sastri M, et al. (2013) A kinase interacting protein (AKIP1) is a key regulator of cardiac stress. Proc Natl Acad Sci USA 110(5):E387-E396.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.5 , pp. E387-E396
    • Sastri, M.1
  • 42
    • 84923375991 scopus 로고    scopus 로고
    • Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy
    • Montero J, et al. (2015) Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy. Cell 160(5):977-989.
    • (2015) Cell , vol.160 , Issue.5 , pp. 977-989
    • Montero, J.1
  • 43
    • 84880371723 scopus 로고    scopus 로고
    • Targeting cAMP in chronic lymphocytic leukemia: A pathway-dependent approach for the treatment of leukemia and lymphoma
    • Murray F, Insel PA (2013) Targeting cAMP in chronic lymphocytic leukemia: A pathway-dependent approach for the treatment of leukemia and lymphoma. Expert Opin Ther Targets 17(8):937-949.
    • (2013) Expert Opin Ther Targets , vol.17 , Issue.8 , pp. 937-949
    • Murray, F.1    Insel, P.A.2
  • 44
    • 84883701893 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury
    • Oikawa M, et al. (2013) Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury. J Mol Cell Cardiol 64:11-19.
    • (2013) J Mol Cell Cardiol , vol.64 , pp. 11-19
    • Oikawa, M.1
  • 45
    • 77954931464 scopus 로고    scopus 로고
    • Differential roles of Epac in regulating cell death in neuronal and myocardial cells
    • Suzuki S, et al. (2010) Differential roles of Epac in regulating cell death in neuronal and myocardial cells. J Biol Chem 285(31):24248-24259.
    • (2010) J Biol Chem , vol.285 , Issue.31 , pp. 24248-24259
    • Suzuki, S.1
  • 46
    • 84873374748 scopus 로고    scopus 로고
    • Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling
    • Zhang X, et al. (2013) Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling. Circ Res 112(3):498-509.
    • (2013) Circ Res , vol.112 , Issue.3 , pp. 498-509
    • Zhang, X.1
  • 47
    • 33747357533 scopus 로고    scopus 로고
    • Switch from caspase-dependent to caspase-independent death during heart development: Essential role of endonuclease G in ischemia-induced DNA processing of differentiated cardiomyocytes
    • Bahi N, et al. (2006) Switch from caspase-dependent to caspase-independent death during heart development: Essential role of endonuclease G in ischemia-induced DNA processing of differentiated cardiomyocytes. J Biol Chem 281(32):22943-22952.
    • (2006) J Biol Chem , vol.281 , Issue.32 , pp. 22943-22952
    • Bahi, N.1
  • 48
    • 78249276849 scopus 로고    scopus 로고
    • Inhibition of NF-κB induces a switch from CD95L-dependent to CD95L-independent and JNK-mediated apoptosis in T cells
    • Kiessling MK, et al. (2010) Inhibition of NF-κB induces a switch from CD95L-dependent to CD95L-independent and JNK-mediated apoptosis in T cells. FEBS Lett 584(22):4679-4688.
    • (2010) FEBS Lett , vol.584 , Issue.22 , pp. 4679-4688
    • Kiessling, M.K.1
  • 49
    • 34447096461 scopus 로고    scopus 로고
    • HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway
    • Tsapis M, et al. (2007) HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway. Int J Biochem Cell Biol 39(7-8):1500-1509.
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.7-8 , pp. 1500-1509
    • Tsapis, M.1
  • 50
    • 84869408163 scopus 로고    scopus 로고
    • Quantitative proteomics analysis of the cAMP/protein kinase A signaling pathway
    • Guo Y, Wilderman A, Zhang L, Taylor SS, Insel PA (2012) Quantitative proteomics analysis of the cAMP/protein kinase A signaling pathway. Biochemistry 51(46):9323-9332.
    • (2012) Biochemistry , vol.51 , Issue.46 , pp. 9323-9332
    • Guo, Y.1    Wilderman, A.2    Zhang, L.3    Taylor, S.S.4    Insel, P.A.5
  • 51
    • 84941309129 scopus 로고    scopus 로고
    • Proteomic and metabolic analyses of S49 lymphoma cells reveal novel regulation of mitochondria by cAMP and protein kinase A
    • Wilderman A, et al. (2015) Proteomic and metabolic analyses of S49 lymphoma cells reveal novel regulation of mitochondria by cAMP and protein kinase A. J Biol Chem 290(36):22274-22286.
    • (2015) J Biol Chem , vol.290 , Issue.36 , pp. 22274-22286
    • Wilderman, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.