Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: The prospective longitudinal trial of FFRCT: Outcome and resource impacts study

European Heart Journal

Volumn 36, Issue 47, 2015, Pages 3359-3367

  Douglas, Pamela S ^a   Pontone, Gianluca ^b   Hlatky, Mark A ^c   Patel, Manesh R ^a   Norgaard, Bjarne L ^d   Byrne, Robert A ^e   Curzen, Nick ^f   Purcell, Ian ^g   Gutberlet, Matthias ^h   Rioufol, Gilles ⁱ   Hink, Ulrich ^j   Schuchlenz, Herwig Walter ^k   Feuchtner, Gudrun ^l   Gilard, Martine ^m   Andreini, Daniele ^b   Jensen, Jesper M ^d   Hadamitzky, Martin ^e   Chiswell, Karen ^a   Cyr, Derek ^a   Wilk, Alan ⁿ   Wang, Furong ⁿ   Rogers, Campbell ⁿ   De Bruyne, Bernard ^o   more..

^a DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d AARHUS UNIVERSITY HOSPITAL   (Denmark)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^g FREEMAN HOSPITAL   (United Kingdom)

^h UNIVERSITY OF LEIPZIG   (Germany)

ⁱ HOSPICES CIVILS DE LYON   (France)

^j UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^k UNIVERSITY HOSPITAL GRAZ   (Austria)

^l INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^m SERVICE DE RHUMATOLOGIE   (France)

ⁿ HEARTFLOW INC   (United States)

^o CARDIOVASCULAR CENTER   (Belgium)

more..

Author keywords

Angina; Coronary computed tomographic angiography; Fractional flow reserve; Non invasive testing

Indexed keywords

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; ATTRIBUTABLE RISK; CARDIOVASCULAR RISK; COHORT ANALYSIS; COMPARATIVE EFFECTIVENESS; COMPUTATIONAL FLUID DYNAMICS; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; CORONARY ARTERY RECANALIZATION; DIABETES MELLITUS; DYSLIPIDEMIA; FEMALE; FRACTIONAL FLOW RESERVE; HEART CATHETERIZATION; HEART INFARCTION; HOSPITALIZATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MYOCARDIAL PERFUSION IMAGING; NONCARDIAC CHEST PAIN; OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION EXPOSURE; THORAX PAIN; TOBACCO USE; ANGINA, STABLE; CLINICAL TRIAL; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ANGIOGRAPHY; FEASIBILITY STUDY; HEART MUSCLE REVASCULARIZATION; LONGITUDINAL STUDY; MULTICENTER STUDY; MYOCARDIAL INFARCTION; PATHOPHYSIOLOGY; PATIENT SELECTION; PHYSIOLOGY; PROCEDURES; STATISTICS AND NUMERICAL DATA; UNNECESSARY PROCEDURE;

ANGINA, STABLE; CARDIAC CATHETERIZATION; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEASIBILITY STUDIES; FEMALE; FRACTIONAL FLOW RESERVE, MYOCARDIAL; HOSPITALIZATION; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL REVASCULARIZATION; PATIENT SELECTION; PROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; UNNECESSARY PROCEDURES;

EID: 84944085387     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehv444     Document Type: Article

References (24)

1. Ladapo JA, Blecker S, Douglas PS. Physician decision-making and trends in the use of cardiac stress testing in the United States: An analysis of repeated cross-sectional data. Ann Intern Med 2014;161:482-490.
2. Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C, Budaj A, Bugiardini R, Crea F, Cuisset T, Di Mario C, Ferreira JR, Gersh BJ, Gitt AK, Hulot JS, Marx N, Opie LH, Pfisterer M, Prescott E, Ruschitzka F, SabatéM, Senior R, Taggart DP, van der Wall EE, Vrints CJ; ESC Committee for Practice Guidelines, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S; Document Reviewers, Knuuti J, Valgimigli M, Bueno H, Claeys MJ, Donner-Banzhoff N, Erol C, Frank H, Funck-Brentano C, Gaemperli O, Gonzalez-Juanatey JR, Hamilos M, Hasdai D, Husted S, James SK, Kervinen K, Kolh P, Kristensen SD, Lancellotti P, Maggioni AP, Piepoli MF, Pries AR, Romeo F, Rydén L, Simoons ML, Sirnes PA, Steg PG, Timmis A, Wijns W, Windecker S, Yildirir A, Zamorano JL. 2013 ESC guidelines on the management of stable coronary artery disease: The Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 2013;34: 2949-3003.
3. Douglas PS, Hoffmann U, Patel MR, Mark DB, Al-Khalidi HR, Cavanaugh B, Cole J, Dolor RJ, Fordyce CB, Huang M, Khan MA, Kosinski AS, Krucoff MW, Malhotra V, Picard MH, Udelson JE, Velazquez EJ, Yow E, Cooper LS, Lee KL; PROMISE Investigators. Outcomes of anatomical versus functional testing for coronary artery disease. N Engl J Med 2015;372:1291-1300.
4. Newby DE on behalf of the SCOT-HEART Investigators. CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): An open-label, parallel-group, multicentre trial. Lancet 2015;385:2383-2391.
5. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. J Am Coll Cardiol 2011;58:e44-e122.
6. Taylor CA, Fonte TA, Min JK. Computational fluid dynamics applied to cardiac computed tomography for non-invasive quantification of fractional flow reserve: scientific basis. J Am Coll Cardiol 2013;61:2233-2241.
7. Koo BK, Erglis A, Doh JH, Daniels DV, Jegere S, Kim HS, Dunning A, DeFrance T, Lansky A, Leipsic J, Min JK. Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained via Noninvasive Fractional Flow Reserve) study. J Am Coll Cardiol 2011;58:1989-1997.
8. Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, Erglis A, Lin FY, Dunning AM, Apruzzese P, Budoff MJ, Cole JH, Jaffer FA, Leon MB, Malpeso J, Mancini GB, Park SJ, Schwartz RS, Shaw LJ, Mauri L. Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. J Am Med Assoc 2012;308: 1237-1245.
9. Nørgaard BL, Leipsic J, Gaur S, Seneviratne S, Ko BS, Ito H, Jensen JM, Mauri L, De Bruyne B, Bezerra H, Osawa K, Marwan M, Naber C, Erglis A, Park SJ, Christiansen EH, Kaltoft A, Lassen JF, Bøtker HE, Achenbach S; NXT Trial Study Group. Diagnostic performance of non-invasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: The NXT trial (Analysis of Coronary Blood Flow Using CT Angiography: Next Steps). J Am Coll Cardiol 2014;63:1145-1155.
10. Pontone G, Patel MR, Hlatky MA, Chiswell K, Andreini D, Norgaard BL, Byrne RA, Curzen N, Purcell I, Gutberlet M, Rioufol G, Hink U, SchuchlenzHW, Feuchtner G, Gilard M, De Bruyne B, Rogers C, Douglas PS. Rationale and design of the PLATFORM (prospective longitudinal trial of FFRCT: outcome and resource impacts) study: design of the PLATFORM study. Am Heart J 2015 (in press).
11. Leipsic J, Abbara S, Achenbach S, Cury R, Earls JP, Mancini GJ, Nieman K, Pontone G, Raff GL. SCCT guidelines for the interpretation and reporting of coronary CT angiography: A report of the Society of Cardiovascular Computed Tomography Guidelines Committee. J Cardiovasc Comput Tomogr 2014;8: 342-358.
12. Tuinenburg JC, Janssen JP, Kooistra R, Koning G, Corral MD, Lansky AJ, Reiber JH. Clinical validation of the new T-And Y-shape models for the quantitative analysis of coronary bifurcations: An interobserver variability study. Catheter Cardiovasc Interv 2013;81:E225-E236.
13. Reiber JH, Kooijman CJ, Slager CJ, Gerbrands JJ, Schuurbiers JC, Den Boer A, WijnsW, Serruys PW, Hugenholtz PG. Coronary artery dimensions from cineangiograms methodology and validation of a computer-Assisted analysis procedure. IEEE Trans Med Imaging 1984;3:131-141.
14. Hicks KA, Tcheng JE, Bozkurt B, Chaitman BR, Cutlip DE, Farb A, Fonarow GC, Jacobs JP, Jaff MR, Lichtman JH, Limacher MC, Mahaffey KW, Mehran R, Nissen SE, Smith EE, Targum SL. 2014 ACC/AHA key data elements and definitions for cardiovascular endpoint events in clinical trials: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Cardiovascular Endpoints Data Standards). J Am Coll Cardiol 2015;66:403-469.
15. Gerber TC, Carr JJ, Arai AE, Dixon RL, Ferrari VA, Gomes AS, Heller GV, McCollough CH, McNitt-Gray MF, Mettler FA, Mieres JH, Morin RL, Yester MV. Ionizing radiation in cardiac imaging: A science advisory from the American Heart Association Committee on Cardiac Imaging of the Council on Clinical Cardiology and Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and intervention. Circulation 2009;119:1056-1065.
16. Genders TS, Steyerberg EW, Alkadhi H, Leschka S, Desbiolles L, Nieman K, Galema TW, Meijboom WB, Mollet NR, de Feyter PJ, Cademartiri F, Maffei E, Dewey M, Zimmermann E, Laule M, Pugliese F, Barbagallo R, Sinitsyn V, Bogaert J, Goetschalckx K, Schoepf UJ, Rowe GW, Schuijf JD, Bax JJ, de Graaf FR, Knuuti J, Kajander S, van Mieghem CA, Meijs MF, Cramer MJ, Gopalan D, Feuchtner G, Friedrich G, Krestin GP, Hunink MG; CAD Consortium. A clinical prediction rule for the diagnosis of coronary artery disease: validation, updating, and extension. Eur Heart J 2011;32:1316-1330.
17. Rosenbaum PR, Rubin DB. Constructing a control group using multivariate matched sampling methods that incorporate the propensity score. Am Stat 1985; 39:33-38.
18. Patel MR, Peterson ED, Dai D, Brennan JM, Redberg RF, Anderson HV, Brindis RG, Douglas PS. Low diagnostic yield of elective coronary angiography. N Engl J Med 2010;362:886-895.
19. Patel MR, Dai D, Hernandez AF, Douglas PS, Messenger J, Garratt KN, Maddox TM, Peterson ED, Roe MT. Prevalence and predictors of non-obstructive coronary artery disease identified with coronary angiography in contemporary clinical practice. Am Heart J 2014;167:846-852.
20. Toth GG, Toth B, Johnson NP, De Vroey F, Di Serafino L, Pyxaras S, Rusinaru D, Di Gioia G, Pellicano M, Barbato E, Van Mieghem C, Heyndrickx GR, De Bruyne B, WijnsW. Revascularization decisions in patients with stable angina and intermediate lesions: results of the International Survey on Interventional Strategy. Circ Cardiovasc Interv 2014;7:751-759.
21. Tonino PA, De Bruyne B, Pijls NH, Siebert U, Ikeno F, vant Veer M, Klauss V, Manoharan G, Engstrøm T, Oldroyd KG, Ver Lee PN, MacCarthy PA, Fearon WF; FAME Study Investigators. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 2009;360:213-224.
22. De Bruyne B, Fearon WF, Pijls NH, Barbato E, Tonino P, Piroth Z, Jagic N, Mobius-Winckler S, Rioufol G, Witt N, Kala P, MacCarthy P, Engström T, Oldroyd K, Mavromatis K, Manoharan G, Verlee P, Frobert O, Curzen N, Johnson JB, Limacher A, Nüesch E, Jüni P; FAME 2 Trial Investigators. Fractional flow reserve-guided PCI for stable coronary artery disease. N Engl J Med 2014; 371:1208-1217.
23. Nallamothu BK, Spertus JA, Lansky AJ, Cohen DJ, Jones PG, Kureshi F, Dehmer GJ, Drozda JP Jr,Walsh MN, Brush JE Jr, Koenig GC,Waites TF, Gantt DS, Kichura G, Chazal RA, OBrien PK, Valentine CM, Rumsfeld JS, Reiber JH, Elmore JG, Krumholz RA, Weaver WD, Krumholz HM. Comparison of clinical interpretation with visual assessment and quantitative coronary angiography in patients undergoing percutaneous coronary intervention in contemporary practice: The Assessing Angiography (A2) project. Circulation 2013;127:1793-1800.
24. Lin GA, Dudley RA, Lucas FL, Malenka DJ, Vittinghoff E, Redberg RF. Frequency of stress testing to document ischemia prior to elective percutaneous coronary intervention. J Am Med Assoc 2008;300:1765-1773.