Ultraviolet C light pathogen inactivation treatment of platelet concentrates preserves integrin activation but affects thrombus formation kinetics on collagen in vitro

Transfusion

Volumn 55, Issue 10, 2015, Pages 2404-2414

  Van Aelst, Britt ^a   Devloo, Rosalie ^a   Vandekerckhove, Philippe ^b,c,d   Compernolle, Veerle ^a,b,d   Feys, Hendrik B ^a  

^a Transfusion Research Center Belgian Red Cross Flanders   (Belgium)

^b Blood Service Belgian Red Cross Flanders   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; COLLAGEN; CONVULXIN; HEXAPEPTIDE; INTEGRIN; INTEGRIN ALPHA 2B BETA 3; LACTIC ACID; LIPOCORTIN 5; PADGEM PROTEIN; PAR1 ACTIVATING HEXAPEPTIDE; RISTOCETIN; THROMBOCYTE CONCENTRATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLOOD CLOTTING; CELL METABOLISM; CONTROLLED STUDY; DEGRANULATION; GAMMA IRRADIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROFLUIDIC ANALYSIS; PATHOGEN CLEARANCE; PH; PROTEIN BINDING; PROTEIN CONFORMATION; THROMBOCYTE AGGREGATION; ULTRAVIOLET C RADIATION; VIDEO MICROSCOPY; ADVERSE EFFECTS; BLOOD SAFETY; DISINFECTION; DRUG EFFECTS; KINETICS; METABOLISM; PROCEDURES; RADIATION RESPONSE; THROMBOCYTE; ULTRAVIOLET RADIATION;

ANNEXIN A5; BLOOD COAGULATION; BLOOD PLATELETS; BLOOD SAFETY; COLLAGEN; DISINFECTION; HUMANS; HYDROGEN-ION CONCENTRATION; INTEGRINS; KINETICS; P-SELECTIN; PLATELET AGGREGATION; ULTRAVIOLET RAYS;

EID: 84943817048     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/trf.13137     Document Type: Article

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