메뉴 건너뛰기




Volumn 92, Issue 5, 1998, Pages 1518-1525

A double-blind randomized comparison of combined aspirin and ticlopidine therapy versus aspirin or ticlopidine alone on experimental arterial thrombogenesis in humans

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; COLLAGEN; FIBRIN; PLACEBO; THROMBOPLASTIN; TICLOPIDINE;

EID: 0032170080     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.5.1518.417k22_1518_1525     Document Type: Article
Times cited : (73)

References (36)
  • 1
    • 0028876995 scopus 로고
    • Aspirin and other plate let-active drugs. the relationship among dose, effectiveness, and side effects
    • suppl
    • Hirsh J, Dalen JE, Fuster V, Harker LA, Patrono C, Roth G: Aspirin and other plate let-active drugs. The relationship among dose, effectiveness, and side effects. Chest 108:2475, 1995 (suppl)
    • (1995) Chest , vol.108 , pp. 2475
    • Hirsh, J.1    Dalen, J.E.2    Fuster, V.3    Harker, L.A.4    Patrono, C.5    Roth, G.6
  • 2
    • 0030055523 scopus 로고    scopus 로고
    • The antiaggregating and antithrombotic activity of ticlopidine is potentiated by aspirin in the rat
    • Herbert JM, Bernat A, Samama M, Maffrand JP: The antiaggregating and antithrombotic activity of ticlopidine is potentiated by aspirin in the rat. Thromb Haemost 76:94, 1996
    • (1996) Thromb Haemost , vol.76 , pp. 94
    • Herbert, J.M.1    Bernat, A.2    Samama, M.3    Maffrand, J.P.4
  • 4
    • 0020554281 scopus 로고
    • A perfusion chamber developed to investigate platelet interaction in flowing blood with human vessel wall cells, their extracellular matrix, and purified components
    • Sakariassen KS, Aarts PAMM, de Groot PG, Houdijk WPM, Sixma JJ: A perfusion chamber developed to investigate platelet interaction in flowing blood with human vessel wall cells, their extracellular matrix, and purified components. J Lab Clin Med 102:522, 1983
    • (1983) J Lab Clin Med , vol.102 , pp. 522
    • Sakariassen, K.S.1    Aarts, P.A.M.M.2    De Groot, P.G.3    Houdijk, W.P.M.4    Sixma, J.J.5
  • 5
  • 6
    • 0028077004 scopus 로고
    • Tissue factor-induced coagulation triggers platelet thrombus formation as efficiently as fibrillar collagen at arterial blood flow condition
    • Orvim U, Roald HE, Stephens RW, Rocs N, Sakariassen KS: Tissue factor-induced coagulation triggers platelet thrombus formation as efficiently as fibrillar collagen at arterial blood flow condition. Arterioscler Thromb 14:1976, 1994
    • (1994) Arterioscler Thromb , vol.14 , pp. 1976
    • Orvim, U.1    Roald, H.E.2    Stephens, R.W.3    Rocs, N.4    Sakariassen, K.S.5
  • 7
    • 0027990650 scopus 로고
    • Effect of blood flow on thrombin generation is dependent on the nature of thrombogenic surface
    • Diquélou A, Lemozy S, Dupouy D, Boneu B, Sakariassen KS, Cadroy Y: Effect of blood flow on thrombin generation is dependent on the nature of thrombogenic surface. Blood 84:2206, 1994
    • (1994) Blood , vol.84 , pp. 2206
    • Diquélou, A.1    Lemozy, S.2    Dupouy, D.3    Boneu, B.4    Sakariassen, K.S.5    Cadroy, Y.6
  • 8
    • 0031984018 scopus 로고    scopus 로고
    • A new method for quantifying platelet deposition in flowing native blood in an ex vivo model of human thrombogenesis
    • Bossavy JP, Sakariassen KS, Barret A, Boneu B, Cadroy Y: A new method for quantifying platelet deposition in flowing native blood in an ex vivo model of human thrombogenesis. Thromb Haemost 79:162, 1998
    • (1998) Thromb Haemost , vol.79 , pp. 162
    • Bossavy, J.P.1    Sakariassen, K.S.2    Barret, A.3    Boneu, B.4    Cadroy, Y.5
  • 11
    • 3543010268 scopus 로고
    • Aspirin ingestion reduces thrombus volume in human nonanticoagulated blood only at shear rates characteristic for stenosed arteries
    • abstr
    • Sakariassen KS, Cousot D, Hadvary P, Baumgartner HR: Aspirin ingestion reduces thrombus volume in human nonanticoagulated blood only at shear rates characteristic for stenosed arteries. Thromb Haemost 65:782, 1991 (abstr)
    • (1991) Thromb Haemost , vol.65 , pp. 782
    • Sakariassen, K.S.1    Cousot, D.2    Hadvary, P.3    Baumgartner, H.R.4
  • 13
    • 0028039963 scopus 로고
    • HN-11500-A novel thromboxane A2 receptor antagonist with antithrombotic activity in humans at arterial blood flow conditions
    • Roald HE, Barstad RM, Engen A, Kierulf P, Skjorten F, Sakariassen KS: HN-11500-A novel thromboxane A2 receptor antagonist with antithrombotic activity in humans at arterial blood flow conditions. Thromb Haemost 71:103, 1994
    • (1994) Thromb Haemost , vol.71 , pp. 103
    • Roald, H.E.1    Barstad, R.M.2    Engen, A.3    Kierulf, P.4    Skjorten, F.5    Sakariassen, K.S.6
  • 14
    • 0028325396 scopus 로고
    • Clopidogrel-A platelet inhibitor which inhibits thrombogenesis in non-anticoagulated human blood independently of the blood flow conditions
    • Roald HE, Barstad RM, Kierulf P, Skjorten F, Dickinson JP, Kieffer G, Sakariassen KS: Clopidogrel-A platelet inhibitor which inhibits thrombogenesis in non-anticoagulated human blood independently of the blood flow conditions. Thromb Haemost 71:103, 1994
    • (1994) Thromb Haemost , vol.71 , pp. 103
    • Roald, H.E.1    Barstad, R.M.2    Kierulf, P.3    Skjorten, F.4    Dickinson, J.P.5    Kieffer, G.6    Sakariassen, K.S.7
  • 15
    • 0001914408 scopus 로고
    • Adhesion and aggregation: Morphological demonstration and quantitation in vivo and in vitro
    • Gordon JE (ed): Amsterdam, Netherlands, Elsevier/North-Holland
    • Baumgartner HR, Muggli R: Adhesion and aggregation: Morphological demonstration and quantitation in vivo and in vitro, in Gordon JE (ed): Platelets in Biology and Pathology. Amsterdam, Netherlands, Elsevier/North-Holland, 1976, p 23
    • (1976) Platelets in Biology and Pathology , pp. 23
    • Baumgartner, H.R.1    Muggli, R.2
  • 17
    • 0029804413 scopus 로고    scopus 로고
    • Immunologic quantification of fibrin deposition in thrombi formed in flowing native human blood
    • Orvim U, Barstad RM, Stormorken H, Brosstad F, Sakariassen KS: Immunologic quantification of fibrin deposition in thrombi formed in flowing native human blood. Br J Haematol 95:389, 1996
    • (1996) Br J Haematol , vol.95 , pp. 389
    • Orvim, U.1    Barstad, R.M.2    Stormorken, H.3    Brosstad, F.4    Sakariassen, K.S.5
  • 18
    • 0030070652 scopus 로고    scopus 로고
    • A randomized comparison of combined ticlopidine and aspirin therapy versus aspirin therapy alone after successful intravascular ultrasound-guided stent implantation
    • Hall P, Nakamura S, Maiello L, Itoh A, Blengino S, Martini G, Ferraro M, Colombo A: A randomized comparison of combined ticlopidine and aspirin therapy versus aspirin therapy alone after successful intravascular ultrasound-guided stent implantation. Circulation 93:215, 1996
    • (1996) Circulation , vol.93 , pp. 215
    • Hall, P.1    Nakamura, S.2    Maiello, L.3    Itoh, A.4    Blengino, S.5    Martini, G.6    Ferraro, M.7    Colombo, A.8
  • 19
    • 0031018569 scopus 로고    scopus 로고
    • Results of a consecutive series of patients receiving only antiplatelet therapy after optimized stent implantation. Comparison of aspirin alone versus combined ticlopidine and aspirin therapy
    • Albiero R, Hall P, Itoh A, Blengino S, Nakamura S, Martini G, Ferraro M, Colombo A: Results of a consecutive series of patients receiving only antiplatelet therapy after optimized stent implantation. Comparison of aspirin alone versus combined ticlopidine and aspirin therapy. Circulation 95:1145, 1997
    • (1997) Circulation , vol.95 , pp. 1145
    • Albiero, R.1    Hall, P.2    Itoh, A.3    Blengino, S.4    Nakamura, S.5    Martini, G.6    Ferraro, M.7    Colombo, A.8
  • 20
    • 0031037125 scopus 로고    scopus 로고
    • Antiplatelet rather than anticoagulant therapy with coronary stenting
    • More RS, Chauhan A: Antiplatelet rather than anticoagulant therapy with coronary stenting. Lancet 349:146, 1997
    • (1997) Lancet , vol.349 , pp. 146
    • More, R.S.1    Chauhan, A.2
  • 22
    • 0342276129 scopus 로고    scopus 로고
    • Major benefit from antiplatelet therapy for patients at high risk for adverse cardiac events after coronary Palmaz-Shatz stent placement
    • Schühlen H, Hadamitzky M, Walter H, Ulm K, Schömig A: Major benefit from antiplatelet therapy for patients at high risk for adverse cardiac events after coronary Palmaz-Shatz stent placement. Circulation 97:2015, 1997
    • (1997) Circulation , vol.97 , pp. 2015
    • Schühlen, H.1    Hadamitzky, M.2    Walter, H.3    Ulm, K.4    Schömig, A.5
  • 23
    • 0024491334 scopus 로고
    • Axial dependence of platelet-collagen interactions in flowing blood. Upstream thrombus growth impairs downstream platelet adhesion
    • Sakariassen KS, Baumgartner HR: Axial dependence of platelet-collagen interactions in flowing blood. Upstream thrombus growth impairs downstream platelet adhesion. Arteriosclerosis 9:33, 1989
    • (1989) Arteriosclerosis , vol.9 , pp. 33
    • Sakariassen, K.S.1    Baumgartner, H.R.2
  • 24
    • 0025904607 scopus 로고
    • Upstream thrombus growth impairs downstream thrombogenesis in non-anticoagulated blood. Effect of procoagulant artery subendothelium and non procoagulant collagen
    • Sakariassen KS, Weiss HJ, Baumgartner HR: Upstream thrombus growth impairs downstream thrombogenesis in non-anticoagulated blood. Effect of procoagulant artery subendothelium and non procoagulant collagen. Thromb Haemost 65:596, 1991
    • (1991) Thromb Haemost , vol.65 , pp. 596
    • Sakariassen, K.S.1    Weiss, H.J.2    Baumgartner, H.R.3
  • 25
    • 0028836874 scopus 로고
    • Axial dependence of collagen-induced thrombus formation in flowing non-anticoagulated human blood. Anti-platelet drugs impair thrombus growth and increase platelet-collagen adhesion
    • Roald HE, Sakariassen KJ: Axial dependence of collagen-induced thrombus formation in flowing non-anticoagulated human blood. Anti-platelet drugs impair thrombus growth and increase platelet-collagen adhesion. Thromb Haemost 73:126, 1995
    • (1995) Thromb Haemost , vol.73 , pp. 126
    • Roald, H.E.1    Sakariassen, K.J.2
  • 26
    • 0030748125 scopus 로고    scopus 로고
    • Mechanisms initiating platelet thrombus formation
    • Ruggeri ZM: Mechanisms initiating platelet thrombus formation. Thromb Haemost 78:611, 1997
    • (1997) Thromb Haemost , vol.78 , pp. 611
    • Ruggeri, Z.M.1
  • 27
    • 0001036199 scopus 로고
    • Ex vivo models for studying thrombosis: Special emphasis on shear rate dependent blood-collagen interactions
    • Hwang NHC, Turitto VT, Yen MRT (eds): New York, NY, Plenum
    • Sakariassen KS, Roald HE, Salatti JA: Ex vivo models for studying thrombosis: Special emphasis on shear rate dependent blood-collagen interactions, in Hwang NHC, Turitto VT, Yen MRT (eds): Advances in Cardiovascular Engineering. New York, NY, Plenum, 1992, p151
    • (1992) Advances in Cardiovascular Engineering , pp. 151
    • Sakariassen, K.S.1    Roald, H.E.2    Salatti, J.A.3
  • 28
    • 1842292745 scopus 로고    scopus 로고
    • Thrombin, fibrin and platelets: A resonance loop in which von Willebrand factor is a necessary link
    • Béguin S, Kumar R: Thrombin, fibrin and platelets: A resonance loop in which von Willebrand factor is a necessary link. Thromb Haemost 78:590, 1997
    • (1997) Thromb Haemost , vol.78 , pp. 590
    • Béguin, S.1    Kumar, R.2
  • 29
    • 0029610423 scopus 로고
    • Effect of selective factor Xa inhibition on arterial thrombus formation triggered by tissue factor/VIIa or collagen in an ex vivo model of shear-dependent human thrombogenesis
    • Orvim U, Barstad RM, Vlasuk GP, Sakariassen KS: Effect of selective factor Xa inhibition on arterial thrombus formation triggered by tissue factor/VIIa or collagen in an ex vivo model of shear-dependent human thrombogenesis. Arterioscler Thromb 15:2188, 1995
    • (1995) Arterioscler Thromb , vol.15 , pp. 2188
    • Orvim, U.1    Barstad, R.M.2    Vlasuk, G.P.3    Sakariassen, K.S.4
  • 31
    • 0031449293 scopus 로고    scopus 로고
    • Role of ADP and thromboxanes in human thrombus formation in ex vivo models
    • Sakariassen KS, Orning L, Stormorken H: Role of ADP and thromboxanes in human thrombus formation in ex vivo models. Platelets 8:385, 1997
    • (1997) Platelets , vol.8 , pp. 385
    • Sakariassen, K.S.1    Orning, L.2    Stormorken, H.3
  • 32
  • 33
    • 0027989732 scopus 로고
    • Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood
    • Gast AG, Tschopp TB, Baumgartner HR: Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood. Arterioscler Thromb 14:1466, 1994
    • (1994) Arterioscler Thromb , vol.14 , pp. 1466
    • Gast, A.G.1    Tschopp, T.B.2    Baumgartner, H.R.3
  • 35
    • 0029782279 scopus 로고    scopus 로고
    • Pharmacodynamics of ticlopidine: Relation between dose and time of administration to platelet inhibition
    • Kuzniar J, Splawinska B, Malinga K, Mazurek AP, Slapwinski J: Pharmacodynamics of ticlopidine: Relation between dose and time of administration to platelet inhibition. Int J Clin Pharmacol Ther 34:357, 1996
    • (1996) Int J Clin Pharmacol Ther , vol.34 , pp. 357
    • Kuzniar, J.1    Splawinska, B.2    Malinga, K.3    Mazurek, A.P.4    Slapwinski, J.5
  • 36
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic event (CAPRIE)
    • Caprie Steering Committee: A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic event (CAPRIE). Lancet 138:1329, 1996
    • (1996) Lancet , vol.138 , pp. 1329


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.