-
1
-
-
84918815964
-
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
-
Ferlay, J. et al. (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer, 136, E359-E386.
-
(2015)
Int. J. Cancer
, vol.136
, pp. E359-E386
-
-
Ferlay, J.1
-
2
-
-
84870195172
-
Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability
-
Wang, H. et al. (2012) Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability. Anticancer. Agents Med. Chem., 12, 1281-1305.
-
(2012)
Anticancer. Agents Med. Chem.
, vol.12
, pp. 1281-1305
-
-
Wang, H.1
-
3
-
-
17644384486
-
Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice
-
Provinciali, M. et al. (2005) Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Int. J. Cancer, 115, 36-45.
-
(2005)
Int. J. Cancer
, vol.115
, pp. 36-45
-
-
Provinciali, M.1
-
4
-
-
33947194048
-
Effect of the silybin-phosphatidylcholine complex (IdB 1016) on the development of mammary tumors in HER-2/neu transgenic mice
-
Provinciali, M. et al. (2007) Effect of the silybin-phosphatidylcholine complex (IdB 1016) on the development of mammary tumors in HER-2/neu transgenic mice. Cancer Res., 67, 2022-2029.
-
(2007)
Cancer Res
, vol.67
, pp. 2022-2029
-
-
Provinciali, M.1
-
5
-
-
84878961367
-
Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice
-
Pierpaoli, E. et al. (2013) Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice. Carcinogenesis, 34, 1352-1360.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1352-1360
-
-
Pierpaoli, E.1
-
6
-
-
50149108987
-
Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine
-
Imanshahidi, M. et al. (2008) Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytother. Res., 22, 999-1012.
-
(2008)
Phytother. Res.
, vol.22
, pp. 999-1012
-
-
Imanshahidi, M.1
-
7
-
-
84906695069
-
Berberine, an epiphany against cancer
-
Guamán-Ortiz, L.M. et al. (2014) Berberine, an epiphany against cancer. Molecules, 19, 12349-12367.
-
(2014)
Molecules
, vol.19
, pp. 12349-12367
-
-
Guamán-Ortiz, L.M.1
-
8
-
-
77956190161
-
Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway
-
Patil, J.B. et al. (2010) Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway. Eur. J. Pharmacol., 645, 70-78.
-
(2010)
Eur. J. Pharmacol.
, vol.645
, pp. 70-78
-
-
Patil, J.B.1
-
9
-
-
32144452226
-
Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3
-
Lin, C.C. et al. (2006) Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3. Anticancer Res., 26, 227-242.
-
(2006)
Anticancer Res
, vol.26
, pp. 227-242
-
-
Lin, C.C.1
-
10
-
-
84923331344
-
Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway
-
Liu, Q. et al. (2015) Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway. Mol. Cancer Ther., 14, 355-363.
-
(2015)
Mol. Cancer Ther.
, vol.14
, pp. 355-363
-
-
Liu, Q.1
-
11
-
-
83155193454
-
Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators
-
Hamsa, T.P. et al. (2012) Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators. Drug Chem. Toxicol., 35, 57-70.
-
(2012)
Drug Chem. Toxicol.
, vol.35
, pp. 57-70
-
-
Hamsa, T.P.1
-
12
-
-
84912028486
-
Berberine reverses epithelial-to-mesenchymal transition and inhibits metastasis and tumor-induced angiogenesis in human cervical cancer cells
-
Chu, S.C. et al. (2014) Berberine reverses epithelial-to-mesenchymal transition and inhibits metastasis and tumor-induced angiogenesis in human cervical cancer cells. Mol. Pharmacol., 86, 609-623.
-
(2014)
Mol. Pharmacol.
, vol.86
, pp. 609-623
-
-
Chu, S.C.1
-
13
-
-
84872765114
-
Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase
-
Yan, L. et al. (2013) Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase. Tumour Biol., 34, 215-221.
-
(2013)
Tumour Biol
, vol.34
, pp. 215-221
-
-
Yan, L.1
-
14
-
-
34447287858
-
Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate
-
Vlodavsky, I. et al. (2007) Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate. Curr. Pharm. Des., 13, 2057-2073.
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 2057-2073
-
-
Vlodavsky, I.1
-
15
-
-
84904170644
-
Multiple effects of berberine derivatives on colon cancer cells
-
Guamán Ortiz, L.M. et al. (2014) Multiple effects of berberine derivatives on colon cancer cells. Biomed Res. Int., 2014, 924585.
-
(2014)
Biomed Res. Int.
, vol.2014
, pp. 924585
-
-
Guamán Ortiz, L.M.1
-
16
-
-
84943777881
-
Benzoquinolizinium salt derivatives as anticancer agents
-
Lombardi, P. et al. (2012) Benzoquinolizinium salt derivatives as anticancer agents. U.S. Pat. 8, 188.
-
(2012)
-
-
Lombardi, P.1
-
17
-
-
24644475793
-
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice
-
Anisimov, V.N. et al. (2005) Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Exp. Gerontol., 40, 685-693.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 685-693
-
-
Anisimov, V.N.1
-
18
-
-
77951210231
-
Gamma-and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression
-
Pierpaoli, E. et al. (2010) Gamma-and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. Life Sci., 86, 668-675.
-
(2010)
Life Sci
, vol.86
, pp. 668-675
-
-
Pierpaoli, E.1
-
19
-
-
36248992450
-
Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation
-
Goedhart, P.T. et al. (2007) Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation. Opt. Express, 15, 15101-15114.
-
(2007)
Opt. Express
, vol.15
, pp. 15101-15114
-
-
Goedhart, P.T.1
-
20
-
-
84920931409
-
Sidestream dark field videomicroscopy for in vivo evaluation of vascularization and perfusion of mammary tumours in HER2/neu transgenic mice
-
Damiani, E. et al. (2015) Sidestream dark field videomicroscopy for in vivo evaluation of vascularization and perfusion of mammary tumours in HER2/neu transgenic mice. Clin. Exp. Pharmacol. Physiol., 42, 225-229.
-
(2015)
Clin. Exp. Pharmacol. Physiol.
, vol.42
, pp. 225-229
-
-
Damiani, E.1
-
21
-
-
0016170419
-
Calculation of the index of acute toxicity by the method of linear regression Comparison with the method of "Karber and Behrens
-
Gilles, H.J. (1974) Calculation of the index of acute toxicity by the method of linear regression. Comparison with the method of "Karber and Behrens". Eur. J. Toxicol. Environ. Hyg., 7, 77-84.
-
(1974)
Eur. J. Toxicol. Environ. Hyg.
, vol.7
, pp. 77-84
-
-
Gilles, H.J.1
-
22
-
-
84870195172
-
Plants against cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability
-
Wang, H. et al. (2012) Plants against cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability. Anticancer Agents Med. Chem., 12, 1281-1305.
-
(2012)
Anticancer Agents Med. Chem.
, vol.12
, pp. 1281-1305
-
-
Wang, H.1
-
23
-
-
84906317330
-
Oxazine derivatives of γ-and δ-tocotrienol display enhanced anticancer activity in vivo
-
Ananthula, S. et al. (2014) Oxazine derivatives of γ-and δ-tocotrienol display enhanced anticancer activity in vivo. Anticancer Res., 34, 2715-2726.
-
(2014)
Anticancer Res
, vol.34
, pp. 2715-2726
-
-
Ananthula, S.1
-
24
-
-
33750489699
-
Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer
-
Ohori, H. et al. (2006) Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol. Cancer Ther., 5, 2563-2571.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2563-2571
-
-
Ohori, H.1
-
25
-
-
84867846281
-
Berberine: new perspectives for old remedies
-
Tillhon, M. et al. (2012) Berberine: new perspectives for old remedies. Biochem. Pharmacol., 84, 1260-1267.
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 1260-1267
-
-
Tillhon, M.1
-
26
-
-
84910661734
-
Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer
-
Jabbarzadeh Kaboli, P. et al. (2014) Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur. J. Pharmacol., 740, 584-595.
-
(2014)
Eur. J. Pharmacol.
, vol.740
, pp. 584-595
-
-
Jabbarzadeh Kaboli, P.1
-
27
-
-
33745526474
-
Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells
-
Letasiová, S. et al. (2006) Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells. Cancer Lett., 239, 254-262.
-
(2006)
Cancer Lett
, vol.239
, pp. 254-262
-
-
Letasiová, S.1
-
28
-
-
0033006804
-
Berberine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of nucleophosmin/B23 and telomerase activity
-
Wu, H.L. et al. (1999) Berberine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of nucleophosmin/B23 and telomerase activity. Int. J. Cancer, 81, 923-929.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 923-929
-
-
Wu, H.L.1
-
29
-
-
77549084786
-
Acute toxicity of berberine and its correlation with the blood concentration in mice
-
Kheir, M.M. et al. (2010) Acute toxicity of berberine and its correlation with the blood concentration in mice. Food Chem. Toxicol., 48, 1105-1110.
-
(2010)
Food Chem. Toxicol.
, vol.48
, pp. 1105-1110
-
-
Kheir, M.M.1
-
30
-
-
0033383597
-
Role of berberine as an adjuvant response modifier during tumour therapy in mice
-
Anis, K.V. et al. (1999) Role of berberine as an adjuvant response modifier during tumour therapy in mice. Pharmaceutical Pharmacology Communications, 5, 697-700.
-
(1999)
Pharmaceutical Pharmacology Communications
, vol.5
, pp. 697-700
-
-
Anis, K.V.1
-
31
-
-
84891368877
-
Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts
-
Tsang, C.M. et al. (2013) Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts. BMC Cancer, 13, 619.
-
(2013)
BMC Cancer
, vol.13
, pp. 619
-
-
Tsang, C.M.1
-
32
-
-
67649438659
-
Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells
-
Choi, M.S. et al. (2009) Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells. Int. J. Oncol., 34, 1221-1230.
-
(2009)
Int. J. Oncol.
, vol.34
, pp. 1221-1230
-
-
Choi, M.S.1
-
33
-
-
84941745695
-
Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice
-
doi:10.1002/mc.22179
-
Li, W. et al. (2014) Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice. Mol. Carcinog., doi:10.1002/mc.22179.
-
(2014)
Mol. Carcinog.
-
-
Li, W.1
-
34
-
-
0023713558
-
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
-
Muller, W.J. et al. (1988) Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell, 54, 105-115.
-
(1988)
Cell
, vol.54
, pp. 105-115
-
-
Muller, W.J.1
-
35
-
-
4944248618
-
Berberine inhibits HIF-1alpha expression via enhanced proteolysis
-
Lin, S. et al. (2004) Berberine inhibits HIF-1alpha expression via enhanced proteolysis. Mol. Pharmacol., 66, 612-619.
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 612-619
-
-
Lin, S.1
|