Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway

Molecular Cancer Therapeutics

Volumn 14, Issue 2, 2015, Pages 355-363

  Liu, Qiao ^a   Xu, Xiuhua ^a   Zhao, Minnan ^a   Wei, Zhao ^a   Li, Xi ^a   Zhang, Xiyu ^a   Liu, Zhaojian ^a   Gong, Yaoqin ^a   Shao, Changshun ^a,b  

^a Shandong Key Laboratory of Digital Human and Clinical Anatomy   (China)

^b Life Sciences Building Rutgers University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BERBERINE; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RNA; TEMOZOLOMIDE; RAF PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; DRUG EFFECT; DRUG INHIBITION; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SENESCENCE; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BAGG ALBINO MOUSE; CELL AGING; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BERBERINE; CELL AGING; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; GLIOBLASTOMA; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE, INBRED BALB C; MICE, NUDE; RAF KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84923331344     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-14-0634     Document Type: Article

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