Structural basis for the discriminative recognition of N6-Methyladenosine RNA by the human YT521-B homology domain family of proteins

Journal of Biological Chemistry

Volumn 290, Issue 41, 2015, Pages 24902-24913

  Xu, Chao ^a   Liu, Ke ^a   Ahmed, Hazem ^a   Loppnau, Peter ^a   Schapira, Matthieu ^a   Min, Jinrong ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINS; NUCLEOTIDES; RNA; YEAST;

BINDING AFFINITIES; DOMAIN-CONTAINING PROTEINS; HOMOLOGY DOMAIN; INTERNAL MODIFICATIONS; SELECTIVE BINDING; SEQUENCE SELECTIVITY; STRUCTURAL BASIS; STRUCTURAL COMPARISON;

PROTEINS;

FUNGAL PROTEIN; N6 METHYLADENOSINE RNA; PHO92 PROTEIN; RNA; UNCLASSIFIED DRUG; YT521 B HOMOLOGY PROTEIN; YTHDC1 PROTEIN; ADENOSINE; ADENOSINE TRIPHOSPHATASE; N(6)-METHYLADENOSINE; NERVE PROTEIN; PHO92 PROTEIN, S CEREVISIAE; RNA BINDING PROTEIN; RNA SPLICING FACTOR; SACCHAROMYCES CEREVISIAE PROTEIN; YTHDC1 PROTEIN, HUMAN; YTHDC2 PROTEIN, HUMAN; YTHDF1 PROTEIN, HUMAN; YTHDF2 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENETIC CONSERVATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN MODIFICATION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; RNA ANALYSIS; RNA SEQUENCE; STRUCTURE ANALYSIS; ANALOGS AND DERIVATIVES; BINDING SITE; CHEMISTRY; CONSERVED SEQUENCE; ENZYME SPECIFICITY; HUMAN; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MOLECULAR MODEL; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

ADENOSINE; ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; RNA; RNA SPLICING FACTORS; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84943742618     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.680389     Document Type: Article

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