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Volumn 156, Issue 10, 2015, Pages 3559-3569

Activation of the GLP-1 receptor by liraglutide increases ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of type 1 diabetes rats

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN[1-7]; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; INSULIN; LIRAGLUTIDE; SURFACTANT PROTEIN A; SURFACTANT PROTEIN B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.1; UNCLASSIFIED DRUG; DIPEPTIDYL CARBOXYPEPTIDASE; SURFACTANT;

EID: 84943643452     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1685     Document Type: Article
Times cited : (147)

References (56)
  • 1
    • 0023107555 scopus 로고
    • Insulinotropin: Glucagon-like peptide i (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas
    • Mojsov S, Weir GC, Habener JF. Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest. 1987; 79(2):616-619.
    • (1987) J Clin Invest. , vol.79 , Issue.2 , pp. 616-619
    • Mojsov, S.1    Weir, G.C.2    Habener, J.F.3
  • 2
    • 0030975613 scopus 로고    scopus 로고
    • Insulinotropic glucagon-like peptide i receptor expression in glucagon-producing β-cells of the rat endocrine pancreas
    • Heller RS, Kieffer TJ, Habener JF. Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing β-cells of the rat endocrine pancreas. Diabetes. 1997;46(5):785-791.
    • (1997) Diabetes. , vol.46 , Issue.5 , pp. 785-791
    • Heller, R.S.1    Kieffer, T.J.2    Habener, J.F.3
  • 3
    • 0030013475 scopus 로고    scopus 로고
    • Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor
    • Bullock BP, Heller RS, Habener JF. Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology. 1996;137(7):2968-2978.
    • (1996) Endocrinology , vol.137 , Issue.7 , pp. 2968-2978
    • Bullock, B.P.1    Heller, R.S.2    Habener, J.F.3
  • 4
    • 67651173077 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus
    • Lovshin JA, Drucker DJ. Incretin-based therapies for type 2 diabetes mellitus. Nat Rev Endocrinol. 2009;5(5):262-269.
    • (2009) Nat Rev Endocrinol. , vol.5 , Issue.5 , pp. 262-269
    • Lovshin, J.A.1    Drucker, D.J.2
  • 5
    • 13344282056 scopus 로고    scopus 로고
    • A role for glucagon-like peptide-1 in the central regulation of feeding
    • Turton MD, O'Shea D, Gunn I, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature. 1996;379(6560): 69-72.
    • (1996) Nature. , vol.379 , Issue.6560 , pp. 69-72
    • Turton, M.D.1    O'Shea, D.2    Gunn, I.3
  • 6
    • 0030068620 scopus 로고    scopus 로고
    • Gastric emptying, glucose responses and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
    • Willms B, Werner J, Holst JJ, Orskov C, Creutzfeldt W, Nauck MA. Gastric emptying, glucose responses and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab. 1996;81(1):327-332.
    • (1996) J Clin Endocrinol Metab. , vol.81 , Issue.1 , pp. 327-332
    • Willms, B.1    Werner, J.2    Holst, J.J.3    Orskov, C.4    Creutzfeldt, W.5    Nauck, M.A.6
  • 8
    • 77954531416 scopus 로고    scopus 로고
    • GLP-1(7-36)-amide and exendin-4 stimulate the HPA axis in rodents and humans
    • Gil-Lozano M, Pérez-Tilve D, Alvarez-Crespo M, et al. GLP-1(7-36)-amide and exendin-4 stimulate the HPA axis in rodents and humans. Endocrinology. 2010;151(6):2629-2640.
    • (2010) Endocrinology , vol.151 , Issue.6 , pp. 2629-2640
    • Gil-Lozano, M.1    Pérez-Tilve, D.2    Alvarez-Crespo, M.3
  • 9
    • 77958052010 scopus 로고    scopus 로고
    • A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells
    • Hattori Y, Jojima T, Tomizawa A, et al. A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells. Diabetologia. 2010;53(10):2256-2263.
    • (2010) Diabetologia. , vol.53 , Issue.10 , pp. 2256-2263
    • Hattori, Y.1    Jojima, T.2    Tomizawa, A.3
  • 10
    • 67650057935 scopus 로고    scopus 로고
    • Along acting glucagonlike peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules
    • Liu H, Dear AE, Knudsen LB, SimpsonRW.Along acting glucagonlike peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules. J Endocrinol. 2009;201(1):59-66.
    • (2009) J Endocrinol. , vol.201 , Issue.1 , pp. 59-66
    • Liu, H.1    Dear, A.E.2    Knudsen, L.B.3    Simpson, R.W.4
  • 11
    • 84874626634 scopus 로고    scopus 로고
    • Pulmonary GLP-1 receptor increases at birth and exogenous GLP-1 receptor agonists augmented surfactant-protein levels in litters from normal and nitrofen-treated pregnant rats
    • Roman-Pérez M, Outeiriño-Iglesias V, Gil-Lozano M, González-Matas LC, Mallo F, Vigo E. Pulmonary GLP-1 receptor increases at birth and exogenous GLP-1 receptor agonists augmented surfactant-protein levels in litters from normal and nitrofen-treated pregnant rats. Endocrinology. 2013;154(3):1144-1155.
    • (2013) Endocrinology , vol.154 , Issue.3 , pp. 1144-1155
    • Roman-Pérez, M.1    Outeiriño-Iglesias, V.2    Gil-Lozano, M.3    González-Matas, L.C.4    Mallo, F.5    Vigo, E.6
  • 12
    • 0031733316 scopus 로고    scopus 로고
    • Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes
    • Benito E, Blazquez E, Bosch MA. Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes. Endocrinology. 1998;139(5): 2363-2368.
    • (1998) Endocrinology , vol.139 , Issue.5 , pp. 2363-2368
    • Benito, E.1    Blazquez, E.2    Bosch, M.A.3
  • 13
    • 1442275322 scopus 로고    scopus 로고
    • Glycemic exposure is associated with reduced pulmonary function in type 2 diabetes: The Fremantle Diabetes Study
    • Davis WA, Knuiman M, Kendall P, Grange V, Davis TM. Glycemic exposure is associated with reduced pulmonary function in type 2 diabetes: the Fremantle Diabetes Study. Diabetes Care. 2004;27(3): 752-757.
    • (2004) Diabetes Care. , vol.27 , Issue.3 , pp. 752-757
    • Davis, W.A.1    Knuiman, M.2    Kendall, P.3    Grange, V.4    Davis, T.M.5
  • 14
    • 0033064232 scopus 로고    scopus 로고
    • Diabetes mellitus induces a thickening of the pulmonary basal lamina
    • Weynand B, Jonckheere A, Frans A, Rahier J. Diabetes mellitus induces a thickening of the pulmonary basal lamina. Respiration. 1999;66:14-19.
    • (1999) Respiration. , vol.66 , pp. 14-19
    • Weynand, B.1    Jonckheere, A.2    Frans, A.3    Rahier, J.4
  • 15
    • 0020549345 scopus 로고
    • Changes in the morphologic features and elasticity caused by streptozotocin-induced diabetes mellitus in growing rats
    • Kida K, Utsuyama M, Takizawa T, ThurlbeckWM.Changes in the morphologic features and elasticity caused by streptozotocin-induced diabetes mellitus in growing rats. Am Rev Respir Dis. 1983; 128(1):125-131.
    • (1983) Am Rev Respir Dis. , vol.128 , Issue.1 , pp. 125-131
    • Kida, K.1    Utsuyama, M.2    Takizawa, T.3    Thurlbeck, W.M.4
  • 16
    • 0036799208 scopus 로고    scopus 로고
    • Diabetes worsens pulmonary diffusion in heart failure, and insulin counteracts this effect
    • Guazzi M., Brambilla R, De Vita S, Guazzi MD. Diabetes worsens pulmonary diffusion in heart failure, and insulin counteracts this effect. Am J Respir Crit Care Med. 2002;166:978-982.
    • (2002) Am J Respir Crit Care Med. , vol.166 , pp. 978-982
    • Guazzi, M.1    Brambilla, R.2    De Vita, S.3    Guazzi, M.D.4
  • 17
    • 28144434185 scopus 로고    scopus 로고
    • The prevalence of pulmonary embolism and pulmonary hypertension in patients with type II diabetes mellitus
    • Movahed MR, Hashemzadeh M, Jamal MM. The prevalence of pulmonary embolism and pulmonary hypertension in patients with type II diabetes mellitus. Chest. 2005;128(5):3568-3571.
    • (2005) Chest. , vol.128 , Issue.5 , pp. 3568-3571
    • Movahed, M.R.1    Hashemzadeh, M.2    Jamal, M.M.3
  • 18
    • 37549068962 scopus 로고    scopus 로고
    • Pathogenic mechanisms of pulmonary arterial hypertension
    • Chan SY, Loscalzo J. Pathogenic mechanisms of pulmonary arterial hypertension. J Mol Cell Cardiol. 2008;44(1):14-30.
    • (2008) J Mol Cell Cardiol. , vol.44 , Issue.1 , pp. 14-30
    • Chan, S.Y.1    Loscalzo, J.2
  • 19
    • 0034050078 scopus 로고    scopus 로고
    • Myocyte death in streptozotocininduced diabetes in rats in angiotensin II-dependent
    • Fiordaliso F, Li B, Latini R, et al. Myocyte death in streptozotocininduced diabetes in rats in angiotensin II-dependent. Lab Invest. 2000;80(4):513-527.
    • (2000) Lab Invest. , vol.80 , Issue.4 , pp. 513-527
    • Fiordaliso, F.1    Li, B.2    Latini, R.3
  • 20
    • 84861099242 scopus 로고    scopus 로고
    • Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: A critical role of the angiotensin II/AT1 receptor axis
    • Patel VB, Bodiga S, Basu R, et al. Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis. Circ Res. 2012;110(10):1322-1335.
    • (2012) Circ Res. , vol.110 , Issue.10 , pp. 1322-1335
    • Patel, V.B.1    Bodiga, S.2    Basu, R.3
  • 21
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renin-angiotensin systems
    • Paul M, Poyan Mehr A, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev. 2006;86(3):747-803.
    • (2006) Physiol Rev. , vol.86 , Issue.3 , pp. 747-803
    • Paul, M.1    Poyan Mehr, A.2    Kreutz, R.3
  • 22
    • 84883331559 scopus 로고    scopus 로고
    • Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopul-monary disease in rats with neonatal hyperoxia-induced lung injury
    • Wagenaar GT, Laghmani el H, Fidder M, et al. Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopul-monary disease in rats with neonatal hyperoxia-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2013;305(5):L341-L351.
    • (2013) Am J Physiol Lung Cell Mol Physiol. , vol.305 , Issue.5 , pp. L341-L351
    • Wagenaar, G.T.1    Laghmani el, H.2    Fidder, M.3
  • 23
    • 0025970577 scopus 로고
    • Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells
    • Kato H, Suzuki H, Tajima S, et al. Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells. J. Hypertens. 1991;9:17-22.
    • (1991) J. Hypertens. , vol.9 , pp. 17-22
    • Kato, H.1    Suzuki, H.2    Tajima, S.3
  • 24
    • 79955565442 scopus 로고    scopus 로고
    • Angiotensin II- induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen activated protein kinase/arginase pathway
    • Shatanawi A, Romero MJ, Iddings JA, et al. Angiotensin II- induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen activated protein kinase/arginase pathway. Am J Physiol. 2011;300(5):C1181-C1192.
    • (2011) Am J Physiol. , vol.300 , Issue.5 , pp. C1181-C1192
    • Shatanawi, A.1    Romero, M.J.2    Iddings, J.A.3
  • 25
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
    • Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol. 2007;292(1):C82-C97.
    • (2007) Am J Physiol Cell Physiol. , vol.292 , Issue.1 , pp. C82-C97
    • Mehta, P.K.1    Griendling, K.K.2
  • 27
    • 48649099066 scopus 로고    scopus 로고
    • Circulating surfactant protein A (SP-A), a marker of lung injury, is associated with insulin resistance
    • Fernández-Real JM, Chico B, Shiratori M, Nara Y, Takahashi H, Ricart W. Circulating surfactant protein A (SP-A), a marker of lung injury, is associated with insulin resistance. Diabetes Care. 2008; 31(5):958-963.
    • (2008) Diabetes Care. , vol.31 , Issue.5 , pp. 958-963
    • Fernández-Real, J.M.1    Chico, B.2    Shiratori, M.3    Nara, Y.4    Takahashi, H.5    Ricart, W.6
  • 28
    • 77953034083 scopus 로고    scopus 로고
    • Surfactant protein D, a marker of lung innate immunity, is positively associated with insulin sensitivity
    • Fernández-Real JM, Valdés S, Manco M, et al. Surfactant protein D, a marker of lung innate immunity, is positively associated with insulin sensitivity. Diabetes Care. 2010;33(4):847-853.
    • (2010) Diabetes Care. , vol.33 , Issue.4 , pp. 847-853
    • Fernández-Real, J.M.1    Valdés, S.2    Manco, M.3
  • 29
    • 0035065281 scopus 로고    scopus 로고
    • Glucagon-like peptide-1(7-36) amide stimulates surfactant secretion in human type II pneumocytes
    • Vara E, Arias-Daz J, Garcia C, Balibrea JL, Blázquez E. Glucagon-like peptide-1(7-36) amide stimulates surfactant secretion in human type II pneumocytes. Am J Respir Crit Care Med. 2001;163(4):840-846.
    • (2001) Am J Respir Crit Care Med. , vol.163 , Issue.4 , pp. 840-846
    • Vara, E.1    Arias-Daz, J.2    Garcia, C.3    Balibrea, J.L.4    Blázquez, E.5
  • 30
    • 0042198675 scopus 로고    scopus 로고
    • B-type natriuretic peptide in cardiovascular disease
    • de Lemos JA, McGuire DK, DraznerMH.B-type natriuretic peptide in cardiovascular disease. Lancet. 2003;362(9380):316-322.
    • (2003) Lancet. , vol.362 , Issue.9380 , pp. 316-322
    • De Lemos, J.A.1    McGuire, D.K.2    Drazner, M.H.3
  • 32
    • 78651230951 scopus 로고    scopus 로고
    • X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/-, hyperhomocysteinemic (CBS-/-) and diabetic (Ins2-/-) mice
    • Givvimani S, Sen U, Tyagi N, Munjal C, Tyagi SC. X-ray imaging of differential vascular density in MMP-9-/-, PAR-1-/-, hyperhomocysteinemic (CBS-/-) and diabetic (Ins2-/-) mice. Arch Physiol Biochem. 2011;117(1):1-7.
    • (2011) Arch Physiol Biochem. , vol.117 , Issue.1 , pp. 1-7
    • Givvimani, S.1    Sen, U.2    Tyagi, N.3    Munjal, C.4    Tyagi, S.C.5
  • 33
    • 0028934922 scopus 로고
    • Lung cell-specific expression of the murine surfactant proteinA (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1
    • Bruno MD, Bohinski RJ, Huelsman KM, Whitsett JA, Korfhagen TR. Lung cell-specific expression of the murine surfactant proteinA (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1. J Biol Chem. 1995;270(12): 6531-6536.
    • (1995) J Biol Chem. , vol.270 , Issue.12 , pp. 6531-6536
    • Bruno, M.D.1    Bohinski, R.J.2    Huelsman, K.M.3    Whitsett, J.A.4    Korfhagen, T.R.5
  • 34
    • 0028024585 scopus 로고
    • The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
    • Bohinski RJ, Di Lauro R, Whitsett JA. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol Cell Biol. 1994;14(9):5671-5681.
    • (1994) Mol Cell Biol. , vol.14 , Issue.9 , pp. 5671-5681
    • Bohinski, R.J.1    Di Lauro, R.2    Whitsett, J.A.3
  • 36
    • 0036230736 scopus 로고    scopus 로고
    • Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetes is associated with reduced stress responsiveness and decreased pituitary and adrenal sensitivity
    • Chan O, Inouye K, Vranic M, Matthews SG. Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetes is associated with reduced stress responsiveness and decreased pituitary and adrenal sensitivity. Endocrinology. 2002;143(5): 1761-1768.
    • (2002) Endocrinology , vol.143 , Issue.5 , pp. 1761-1768
    • Chan, O.1    Inouye, K.2    Vranic, M.3    Matthews, S.G.4
  • 39
    • 0022496358 scopus 로고
    • Altered phospholipid biosynthesis in type II pneumocytes isolated from streptozotocin-diabetic rats
    • Uhal BD, Longmore WJ. Altered phospholipid biosynthesis in type II pneumocytes isolated from streptozotocin-diabetic rats. Biochim Biophys Acta. 1986;878(2):266-272.
    • (1986) Biochim Biophys Acta. , vol.878 , Issue.2 , pp. 266-272
    • Uhal, B.D.1    Longmore, W.J.2
  • 40
    • 0022496356 scopus 로고
    • Altered phospholipid secretion in type II pneumocytes isolated from streptozotocin-diabetic rats
    • Brown LA, Longmore WJ. Altered phospholipid secretion in type II pneumocytes isolated from streptozotocin-diabetic rats. Biochim Biophys Acta. 1986;878(2):258-265.
    • (1986) Biochim Biophys Acta. , vol.878 , Issue.2 , pp. 258-265
    • Brown, L.A.1    Longmore, W.J.2
  • 41
    • 0023197330 scopus 로고
    • Adenosine 3',5'-monophosphate analogs and β-adrenergic agonists induce the synthesis of the major surfactant apoprotein in human fetal lung in vitro
    • OdomMJ, Snyder JM, Mendelson CR. Adenosine 3',5'-monophosphate analogs and β-adrenergic agonists induce the synthesis of the major surfactant apoprotein in human fetal lung in vitro. Endocrinology. 1987;121(3):1155-1163.
    • (1987) Endocrinology , vol.121 , Issue.3 , pp. 1155-1163
    • Odom, M.J.1    Snyder, J.M.2    Mendelson, C.R.3
  • 43
    • 0028520782 scopus 로고
    • Differential expressions of surfactant protein SP-A, SP-B, and SP-C mRNAs in rats with streptozotocin-induced diabetes demonstrated by in situ hybridization
    • Sugahara K, Iyama K, Sano K, Morioka T. Differential expressions of surfactant protein SP-A, SP-B, and SP-C mRNAs in rats with streptozotocin-induced diabetes demonstrated by in situ hybridization. Am J Respir Cell Mol Biol. 1994;11(4):397-404.
    • (1994) Am J Respir Cell Mol Biol. , vol.11 , Issue.4 , pp. 397-404
    • Sugahara, K.1    Iyama, K.2    Sano, K.3    Morioka, T.4
  • 44
    • 0033031057 scopus 로고    scopus 로고
    • Glucose decreases steady state mRNA content of hydrophobic surfactant proteins B and C in fetal rat lung explants
    • Rayani HH, Gewolb IH, Floros J. Glucose decreases steady state mRNA content of hydrophobic surfactant proteins B and C in fetal rat lung explants. Exp Lung Res. 1999;25(1):69-79.
    • (1999) Exp Lung Res. , vol.25 , Issue.1 , pp. 69-79
    • Rayani, H.H.1    Gewolb, I.H.2    Floros, J.3
  • 45
    • 0026829230 scopus 로고
    • Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocininduced diabetic rats demonstrated by in situ hybridization
    • Sugahara K, Iyama K, Sano K, Morioka T. Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocininduced diabetic rats demonstrated by in situ hybridization. Am J Respir Cell Mol Biol. 1992;6(3):307-314.
    • (1992) Am J Respir Cell Mol Biol. , vol.6 , Issue.3 , pp. 307-314
    • Sugahara, K.1    Iyama, K.2    Sano, K.3    Morioka, T.4
  • 46
    • 84888221584 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) reduces mortality and improves lung function in a model of experimental obstructive lung disease in female mice
    • Viby NE, Isidor MS, Buggeskov KB, Poulsen SS, Hansen JB, Kissow H. Glucagon-like peptide-1 (GLP-1) reduces mortality and improves lung function in a model of experimental obstructive lung disease in female mice. Endocrinology. 2013;154(12):4503-4511.
    • (2013) Endocrinology , vol.154 , Issue.12 , pp. 4503-4511
    • Viby, N.E.1    Isidor, M.S.2    Buggeskov, K.B.3    Poulsen, S.S.4    Hansen, J.B.5    Kissow, H.6
  • 47
    • 1842737696 scopus 로고    scopus 로고
    • Effects of acute and chronic administration of β-adrenoceptor ligands on airway function in a murine model of asthma
    • Callaerts-Vegh Z, Evans KL, Dudekula N, et al. Effects of acute and chronic administration of β-adrenoceptor ligands on airway function in a murine model of asthma. Proc Natl Acad Sci USA. 2004; 101(14):4948-4953.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , Issue.14 , pp. 4948-4953
    • Callaerts-Vegh, Z.1    Evans, K.L.2    Dudekula, N.3
  • 48
    • 4644249772 scopus 로고    scopus 로고
    • Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin
    • Nogueiras R, Tovar S, Mitchell SE, et al. Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin. Diabetes. 2004;53(10):2552-2558.
    • (2004) Diabetes. , vol.53 , Issue.10 , pp. 2552-2558
    • Nogueiras, R.1    Tovar, S.2    Mitchell, S.E.3
  • 49
    • 66249133083 scopus 로고    scopus 로고
    • Evidence for angiotensinconverting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension
    • Ferreira AJ, Shenoy V, Yamazato Y, et al. Evidence for angiotensinconverting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension. Am J Respir Crit Care Med. 2009; 179(11):1048-1054.
    • (2009) Am J Respir Crit Care Med. , vol.179 , Issue.11 , pp. 1048-1054
    • Ferreira, A.J.1    Shenoy, V.2    Yamazato, Y.3
  • 50
    • 0032886630 scopus 로고    scopus 로고
    • Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT1 receptors
    • Morrel NW, Upton PD, Kotecha S, et al. Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT1 receptors. Am J Physiol. 1999;277(3 pt 1):L440-L448.
    • (1999) Am J Physiol. , vol.277 , Issue.3 , pp. L440-L448
    • Morrel, N.W.1    Upton, P.D.2    Kotecha, S.3
  • 51
    • 44449165530 scopus 로고    scopus 로고
    • Targeting tissue angiotensin-converting enzyme for imaging cardiopulmonary fibrosis
    • Aras O, Dilsizian V. Targeting tissue angiotensin-converting enzyme for imaging cardiopulmonary fibrosis. Curr Cardiol Rep. 2008; 10(2):128-134.
    • (2008) Curr Cardiol Rep. , vol.10 , Issue.2 , pp. 128-134
    • Aras, O.1    Dilsizian, V.2
  • 53
    • 0026605307 scopus 로고
    • In vivo metabolism of angiotensin i by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats
    • Yamamoto K, Chappell MC, Brosnihan KB, Ferrario CM. In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats. Hypertension. 1992; 19:692-696.
    • (1992) Hypertension. , vol.19 , pp. 692-696
    • Yamamoto, K.1    Chappell, M.C.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 54
    • 84863997473 scopus 로고    scopus 로고
    • Renin-angiotensin system blockade: A novel therapeutic approach in chronic obstructive pulmonary disease
    • Shrikrishna D, Astin R, Kemp PR, Hopkinson NS. Renin-angiotensin system blockade: a novel therapeutic approach in chronic obstructive pulmonary disease. Clin Sci (Lond). 2012;123(8):487-498.
    • (2012) Clin Sci (Lond). , vol.123 , Issue.8 , pp. 487-498
    • Shrikrishna, D.1    Astin, R.2    Kemp, P.R.3    Hopkinson, N.S.4
  • 55
    • 80052001034 scopus 로고    scopus 로고
    • Local renin-angiotensin II systems, angiotensin-converting enzyme and its homologue ACE2: Their potential role in the pathogenesis of chronic obstructive pulmonary diseases, pulmonary hypertension and acute respiratory distress syndrome
    • Kaparianos A, Argyropoulou E. Local renin-angiotensin II systems, angiotensin-converting enzyme and its homologue ACE2: their potential role in the pathogenesis of chronic obstructive pulmonary diseases, pulmonary hypertension and acute respiratory distress syndrome. Curr Med Chem. 2011;18(23):3506-3515.
    • (2011) Curr Med Chem. , vol.18 , Issue.23 , pp. 3506-3515
    • Kaparianos, A.1    Argyropoulou, E.2
  • 56
    • 79954416675 scopus 로고    scopus 로고
    • ACE2, a promising therapeutic target for pulmonary hypertension
    • Shenoy V, Qi Y, Katovich MJ, Raizada MK. ACE2, a promising therapeutic target for pulmonary hypertension. Curr Opin Pharmacol. 2011;11(2):150-155.
    • (2011) Curr Opin Pharmacol. , vol.11 , Issue.2 , pp. 150-155
    • Shenoy, V.1    Qi, Y.2    Katovich, M.J.3    Raizada, M.K.4


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