Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Molecular Medicine Reports

Volumn 12, Issue 5, 2015, Pages 6591-6597

  Yao, Junchao ^a   Zheng, Kebin ^b   Zhang, Xiang ^a  

^a CANGZHOU CENTRAL HOSPITAL   (China)

^b HEBEI UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Inflammatory; Neuroprotection; Rats; Rosiglitazone; Traumatic brain injury

Indexed keywords

BECLIN 1; INTERLEUKIN 6; ROSIGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; VESICULAR GLUTAMATE TRANSPORTER 1; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIINFLAMMATORY AGENT; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, RAT; CASPASE 3; NEUROPROTECTIVE AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BCL 2; TUMOR NECROSIS FACTOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN CORTEX; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; MOTOR PERFORMANCE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; TRAUMATIC BRAIN INJURY; UPREGULATION; WESTERN BLOTTING; AGONISTS; ANIMAL; BRAIN; BRAIN INJURIES; DISEASE MODEL; DRUG EFFECTS; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; BRAIN; BRAIN INJURIES; CASPASE 3; DISEASE MODELS, ANIMAL; FEMALE; INTERLEUKIN-6; NEUROPROTECTIVE AGENTS; PPAR GAMMA; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; THIAZOLIDINEDIONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84943629500     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4292     Document Type: Article

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