Role of Tissue Factor in the Coagulation Network

Seminars in Thrombosis and Hemostasis

Volumn 41, Issue 7, 2015, Pages 708-717

  Cimmino, Giovanni ^a   Ciccarelli, Giovanni ^a   Golino, Paolo ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

atherothrombosis; coagulation cascade; thrombus formation; tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; PROTEINASE; THROMBIN; THROMBOPLASTIN; TISSUE FACTOR PATHWAY INHIBITOR;

ALTERNATIVE RNA SPLICING; ANGIOGENESIS; ATHEROSCLEROSIS; BLOOD CLOTTING; BLOOD VESSEL WALL; CELL PROLIFERATION; COMPLEX FORMATION; CONFERENCE PAPER; HUMAN; INFLAMMATION; INTRACELLULAR SIGNALING; LEUKOCYTE; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; THROMBOCYTE; THROMBOGENICITY; THROMBUS; UPREGULATION; ACUTE CORONARY SYNDROME; ANIMAL; ATHEROSCLEROTIC PLAQUE; MEMBRANE MICROPARTICLE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; THROMBOSIS;

ACUTE CORONARY SYNDROME; ANIMALS; BLOOD COAGULATION; BLOOD PLATELETS; CELL PROLIFERATION; CELL-DERIVED MICROPARTICLES; FACTOR VIIA; FACTOR XA; HUMANS; PLAQUE, ATHEROSCLEROTIC; SIGNAL TRANSDUCTION; THROMBOPLASTIN; THROMBOSIS;

EID: 84943621559     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0035-1564045     Document Type: Conference Paper

References (102)

1. Toschi V., Gallo R., Lettino M., et al. Tissue factor modulates the thrombogenicity of human atherosclerotic plaques. Circulation: 1997; 95 3 594 599
2. Cimmino G., D'Amico C., Vaccaro V., D'Anna M., Golino P. The missing link between atherosclerosis, inflammation and thrombosis: is it tissue factor? Expert Rev Cardiovasc Ther: 2011; 9 4 517 523
3. Cimmino G., Golino P., Badimon J. J. Pathophysiological role of blood-borne tissue factor: should the old paradigm be revisited? Intern Emerg Med: 2011; 6 1 29 34
4. Cirillo P., Calì G., Golino P., et al. Tissue factor binding of activated factor VII triggers smooth muscle cell proliferation via extracellular signal-regulated kinase activation. Circulation: 2004; 109 23 2911 2916
5. van den Berg Y. W., Versteeg H. H. Alternatively spliced tissue factor. A crippled protein in coagulation or a key player in non-haemostatic processes? Hamostaseologie: 2010; 30 3 144 149
6. van den Berg Y. W., van den Hengel L. G., Myers H. R., et al. Alternatively spliced tissue factor induces angiogenesis through integrin ligation. Proc Natl Acad Sci U S A: 2009; 106 46 19497 19502
7. Chu A. J. Tissue factor, blood coagulation, and beyond: an overview. Int J Inflamm: 2011; 2011 367284
8. Bächli E. History of tissue factor. Br J Haematol: 2000; 110 2 248 255
9. Davie E. W. A brief historical review of the waterfall/cascade of blood coagulation. J Biol Chem: 2003; 278 51 50819 50832
10. Beck E. A. The chemistry of blood coagulation: a summary by Paul Morawitz (1905). Thromb Haemost: 1977; 37 3 376 379
11. Horne R. M. The action of calcium, strontium and barium salts in preventing coagulation of the blood. J Physiol: 1896; 19 4 356 371
12. Hjort P. F. Intermediate reactions in the coagulation of blood with tissue thromboplastin; convertin, accelerin, prothrombinase. Scand J Clin Lab Invest: 1957; 9 27 1 183
13. Quick A. J. The one-stage prothrombin time determination. Its history and interpretation. Chemotherapia (Basel): 1961; 3 313 320
14. Nemerson Y. The reaction between bovine brain tissue factor and factors VII and X. Biochemistry: 1966; 5 2 601 608
15. Broze G. Jr.J., Leykam J. E., Schwartz B. D., Miletich J. P. Purification of human brain tissue factor. J Biol Chem: 1985; 260 20 10917 10920
16. Fisher K. L., Gorman C. M., Vehar G. A., O'Brien D. P., Lawn R. M. Cloning and expression of human tissue factor cDNA. Thromb Res: 1987; 48 1 89 99
17. Morrissey J. H., Fakhrai H., Edgington T. S. Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade. Cell: 1987; 50 1 129 135
18. Scarpati E. M., Wen D., Broze G.Jr.J., et al. Human tissue factor: cDNA sequence and chromosome localization of the gene. Biochemistry: 1987; 26 17 5234 5238
19. Spicer E. K., Horton R., Bloem L., et al. Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA. Proc Natl Acad Sci U S A: 1987; 84 15 5148 5152
20. Bazan J. F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci U S A: 1990; 87 18 6934 6938
21. Mackman N., Morrissey J. H., Fowler B., Edgington T. S. Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade. Biochemistry: 1989; 28 4 1755 1762
22. Paborsky L. R., Caras I. W., Fisher K. L., Gorman C. M. Lipid association, but not the transmembrane domain, is required for tissue factor activity. Substitution of the transmembrane domain with a phosphatidylinositol anchor. J Biol Chem: 1991; 266 32 21911 21916
23. Sharma L., Melis E., Hickey M. J., et al. The cytoplasmic domain of tissue factor contributes to leukocyte recruitment and death in endotoxemia. Am J Pathol: 2004; 165 1 331 340
24. Paborsky L. R., Tate K. M., Harris R. J., et al. Purification of recombinant human tissue factor. Biochemistry: 1989; 28 20 8072 8077
25. Drake T. A., Morrissey J. H., Edgington T. S. Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Am J Pathol: 1989; 134 5 1087 1097
26. Fleck R. A., Rao L. V., Rapaport S. I., Varki N. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res: 1990; 59 2 421 437
27. Broze G. Jr.J., Majerus P. W. Purification and properties of human coagulation factor VII. J Biol Chem: 1980; 255 4 1242 1247
28. Gladhaug A., Prydz H. Purification of the coagulation factors VII and X from human serum. Some properties of factor VII. Biochim Biophys Acta: 1970; 215 1 105 111
29. Vadivel K., Bajaj S. P. Structural biology of factor VIIa/tissue factor initiated coagulation. Front Biosci (Landmark Ed): 2012; 17 2476 2494
30. Radcliffe R., Nemerson Y. Activation and control of factor VII by activated factor X and thrombin. Isolation and characterization of a single chain form of factor VII. J Biol Chem: 1975; 250 2 388 395
31. Rao L. V., Bajaj S. P., Rapaport S. I. Activation of human factor VII during clotting in vitro. Blood: 1985; 65 1 218 226
32. Sabharwal A. K., Birktoft J. J., Gorka J., Wildgoose P., Petersen L. C., Bajaj S. P. High affinity Ca(2+)-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity. J Biol Chem: 1995; 270 26 15523 15530
33. Irie A., Takahashi S., Katayama Y., Ito K., Miyake Y. Human urinary prokallikrein: rapid purification and model activation by trypsin. Biochem Int: 1986; 13 2 375 382
34. Ruf W., Rehemtulla A., Morrissey J. H., Edgington T. S. Phospholipid-independent and -dependent interactions required for tissue factor receptor and cofactor function. J Biol Chem: 1991; 266 4 2158 2166
35. Fiore M. M., Neuenschwander P. F., Morrissey J. H. The biochemical basis for the apparent defect of soluble mutant tissue factor in enhancing the proteolytic activities of factor VIIa. J Biol Chem: 1994; 269 1 143 149
36. Zhong D., Bajaj M. S., Schmidt A. E., Bajaj S. P. The N-terminal epidermal growth factor-like domain in factor IX and factor X represents an important recognition motif for binding to tissue factor. J Biol Chem: 2002; 277 5 3622 3631
37. Wilkinson F. H., Ahmad S. S., Walsh P. N. The factor IXa second epidermal growth factor (EGF2) domain mediates platelet binding and assembly of the factor X activating complex. J Biol Chem: 2002; 277 8 5734 5741
38. Giesen P. L., Rauch U., Bohrmann B., et al. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A: 1999; 96 5 2311 2315
39. Osterud B., Bjorklid E. Sources of tissue factor. Semin Thromb Hemost: 2006; 32 1 11 23
40. Brambilla M., Camera M., Colnago D., et al. Tissue factor in patients with acute coronary syndromes: expression in platelets, leukocytes, and platelet-leukocyte aggregates. Arterioscler Thromb Vasc Biol: 2008; 28 5 947 953
41. Lechner D., Weltermann A. Circulating tissue factor-exposing microparticles. Thromb Res: 2008; 122 01 S47 S54
42. Bogdanov V. Y., Balasubramanian V., Hathcock J., Vele O., Lieb M., Nemerson Y. Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med: 2003; 9 4 458 462
43. Rivers R. P., Hathaway W. E., Weston W. L. The endotoxin-induced coagulant activity of human monocytes. Br J Haematol: 1975; 30 3 311 316
44. Maugeri N., Brambilla M., Camera M., et al. Human polymorphonuclear leukocytes produce and express functional tissue factor upon stimulation. J Thromb Haemost: 2006; 4 6 1323 1330
45. Sovershaev M. A., Lind K. F., Devold H., et al. No evidence for the presence of tissue factor in high-purity preparations of immunologically isolated eosinophils. J Thromb Haemost: 2008; 6 10 1742 1749
46. Darbousset R., Thomas G. M., Mezouar S., et al. Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation. Blood: 2012; 120 10 2133 2143
47. Egorina E. M., Sovershaev M. A., Olsen J. O., Osterud B. Granulocytes do not express but acquire monocyte-derived tissue factor in whole blood: evidence for a direct transfer. Blood: 2008; 111 3 1208 1216
48. Bouchard B. A., Mann K. G., Butenas S. No evidence for tissue factor on platelets. Blood: 2010; 116 5 854 855
49. Camera M., Brambilla M., Toschi V., Tremoli E. Tissue factor expression on platelets is a dynamic event. Blood: 2010; 116 23 5076 5077
50. Zillmann A., Luther T., Müller I., et al. Platelet-associated tissue factor contributes to the collagen-triggered activation of blood coagulation. Biochem Biophys Res Commun: 2001; 281 2 603 609
51. Weyrich A. S., Lindemann S., Tolley N. D., et al. Change in protein phenotype without a nucleus: translational control in platelets. Semin Thromb Hemost: 2004; 30 4 491 498
52. Mezzano D., Panes O. Regulation of platelet-expressed tissue factor. J Thromb Haemost: 2009; 7 02 Abstract AS-MO-041
53. Camera M., Frigerio M., Toschi V., et al. Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs. Arterioscler Thromb Vasc Biol: 2003; 23 9 1690 1696
54. Camera M., Brambilla M., Facchinetti L., et al. Tissue factor and atherosclerosis: not only vessel wall-derived TF, but also platelet-associated TF. Thromb Res: 2012; 129 3 279 284
55. Schwertz H., Tolley N. D., Foulks J. M., et al. Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. J Exp Med: 2006; 203 11 2433 2440
56. Rauch U., Nemerson Y. Circulating tissue factor and thrombosis. Curr Opin Hematol: 2000; 7 5 273 277
57. Cimmino G. BG, Conte S., Pellegrino G., et al. Expression of Functional Tissue Factor in Activated T-Lymphocytes: A Contribution to Thrombosis? ACC Scientific Session; 2014
58. Chargaff E., West R. The biological significance of the thromboplastic protein of blood. J Biol Chem: 1946; 166 1 189 197
59. Biró E., Sturk-Maquelin K. N., Vogel G. M., et al. Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner. J Thromb Haemost: 2003; 1 12 2561 2568
60. Davizon P., López J. A. Microparticles and thrombotic disease. Curr Opin Hematol: 2009; 16 5 334 341
61. Reininger A. J., Bernlochner I., Penz S. M., et al. A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques. J Am Coll Cardiol: 2010; 55 11 1147 1158
62. Day S. M., Reeve J. L., Pedersen B., et al. Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood: 2005; 105 1 192 198
63. Balasubramanian V., Grabowski E., Bini A., Nemerson Y. Platelets, circulating tissue factor, and fibrin colocalize in ex vivo thrombi: real-time fluorescence images of thrombus formation and propagation under defined flow conditions. Blood: 2002; 100 8 2787 2792
64. Bach R. R. Tissue factor encryption. Arterioscler Thromb Vasc Biol: 2006; 26 3 456 461
65. Ploplis V. A., Edgington T. S., Fair D. S. Initiation of the extrinsic pathway of coagulation. Association of factor VIIa with a cell line expressing tissue factor. J Biol Chem: 1987; 262 20 9503 9508
66. Sakai T., Lund-Hansen T., Paborsky L., Pedersen A. H., Kisiel W. Binding of human factors VII and VIIa to a human bladder carcinoma cell line (J82). Implications for the initiation of the extrinsic pathway of blood coagulation. J Biol Chem: 1989; 264 17 9980 9988
67. Le D. T., Rapaport S. I., Rao L. V. Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces. J Biol Chem: 1992; 267 22 15447 15454
68. Henriksson C. E., Klingenberg O., Hellum M., et al. Calcium ionophore-induced de-encryption of tissue factor in monocytes is associated with extensive cell death. Thromb Res: 2007; 119 5 621 630
69. Mallat Z., Hugel B., Ohan J., Lesèche G., Freyssinet J. M., Tedgui A. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation: 1999; 99 3 348 353
70. Leroyer A. S., Isobe H., Lesèche G., et al. Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques. J Am Coll Cardiol: 2007; 49 7 772 777
71. Berckmans R. J., Nieuwland R., Böing A. N., Romijn F. P., Hack C. E., Sturk A. Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb Haemost: 2001; 85 4 639 646
72. Giannarelli C., Alique M., Rodriguez D. T., et al. Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling. Circulation: 2014; 130 15 1274 1286
73. Bogdanov V. Y., Cimmino G., Tardos J. G., Tunstead J. R., Badimon J. J. Assessment of plasma tissue factor activity in patients presenting with coronary artery disease: limitations of a commercial assay. J Thromb Haemost: 2009; 7 5 894 897
74. Cimmino G., et al. Decreased blood-borne tissue factor activity in patients presenting with acute coronary syndrome: should the old paradigm be revisited? Circulation: 2010; 122 A19396
75. Broze G. Jr.J. The rediscovery and isolation of TFPI. J Thromb Haemost: 2003; 1 8 1671 1675
76. Broze G. Jr. J., Girard T. J. Tissue factor pathway inhibitor: structure-function. Front Biosci (Landmark Ed): 2012; 17 262 280
77. Golino P., Ragni M., Cimmino G., Forte L. Role of tissue factor pathway inhibitor in the regulation of tissue factor-dependent blood coagulation. Cardiovasc Drug Rev: 2002; 20 1 67 80
78. Girard T. J., Warren L. A., Novotny W. F., et al. Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor. Nature: 1989; 338 6215 518 520
79. Wesselschmidt R., Likert K., Girard T., Wun T. C., Broze G. Jr.J. Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa. Blood: 1992; 79 8 2004 2010
80. Wesselschmidt R., Likert K., Huang Z., MacPhail L., Broze G. Jr.J. Structural requirements for tissue factor pathway inhibitor interactions with factor Xa and heparin. Blood Coagul Fibrinolysis: 1993; 4 5 661 669
81. Piro O., Broze G. Jr.J. Role for the Kunitz-3 domain of tissue factor pathway inhibitor-alpha in cell surface binding. Circulation: 2004; 110 23 3567 3572
82. Baugh R. J., Broze G. Jr.J. , Krishnaswamy S. Regulation of extrinsic pathway factor Xa formation by tissue factor pathway inhibitor. J Biol Chem: 1998; 273 8 4378 4386
83. Lesnik P., Vonica A., Guérin M., Moreau M., Chapman M. J. Anticoagulant activity of tissue factor pathway inhibitor in human plasma is preferentially associated with dense subspecies of LDL and HDL and with Lp(a). Arterioscler Thromb: 1993; 13 7 1066 1075
84. Novotny W. F., Girard T. J., Miletich J. P., Broze G. Jr.J. Purification and characterization of the lipoprotein-associated coagulation inhibitor from human plasma. J Biol Chem: 1989; 264 31 18832 18837
85. Novotny W. F., Girard T. J., Miletich J. P., Broze G. J. Jr. Platelets secrete a coagulation inhibitor functionally and antigenically similar to the lipoprotein associated coagulation inhibitor. Blood: 1988; 72 6 2020 2025
86. Sandset P. M., Abildgaard U., Larsen M. L. Heparin induces release of extrinsic coagulation pathway inhibitor (EPI). Thromb Res: 1988; 50 6 803 813
87. Ellery P. E., Hardy K., Oostryck R., Adams M. J. Further insight into the heparin-releasable and glycosylphosphatidylinositol-lipid-anchored forms of tissue factor pathway inhibitor. Clin Appl Thromb Hemost: 2008; 14 3 267 278
88. Golino P., Cimmino G. Targeting tissue factor as an antithrombotic strategy. Semin Vasc Med: 2003; 3 2 205 214
89. Ragni M., Golino P., Cirillo P., et al. Endogenous tissue factor pathway inhibitor modulates thrombus formation in an in vivo model of rabbit carotid artery stenosis and endothelial injury. Circulation: 2000; 102 1 113 117
90. Haskel E. J., Torr S. R., Day K. C., et al. Prevention of arterial reocclusion after thrombolysis with recombinant lipoprotein-associated coagulation inhibitor. Circulation: 1991; 84 2 821 827
91. Oltrona L., Speidel C. M., Recchia D., Wickline S. A., Eisenberg P. R., Abendschein D. R. Inhibition of tissue factor-mediated coagulation markedly attenuates stenosis after balloon-induced arterial injury in minipigs. Circulation: 1997; 96 2 646 652
92. Golino P., Cirillo P., Calabro P., et al. Expression of exogenous tissue factor pathway inhibitor in vivo suppresses thrombus formation in injured rabbit carotid arteries. J Am Coll Cardiol: 2001; 38 2 569 576
93. Versteeg H. H., Spek C. A., Peppelenbosch M. P., Richel D. J. Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways. Mol Med: 2004; 10 1-6 6 11
94. Antoniak S., Pawlinski R., Mackman N. Protease-activated receptors and myocardial infarction. IUBMB Life: 2011; 63 6 383 389
95. Borissoff J. I., Spronk H. M., ten Cate H. The hemostatic system as a modulator of atherosclerosis. N Engl J Med: 2011; 364 18 1746 1760
96. Pyo R. T., Sato Y., Mackman N., Taubman M. B. Mice deficient in tissue factor demonstrate attenuated intimal hyperplasia in response to vascular injury and decreased smooth muscle cell migration. Thromb Haemost: 2004; 92 3 451 458
97. Demetz G., Seitz I., Stein A., et al. Tissue Factor-Factor VIIa complex induces cytokine expression in coronary artery smooth muscle cells. Atherosclerosis: 2010; 212 2 466 471
98. Ardissino D., Merlini P. A., Ariëns R., Coppola R., Bramucci E., Mannucci P. M. Tissue-factor antigen and activity in human coronary atherosclerotic plaques. Lancet: 1997; 349 9054 769 771
99. Hutter R., Valdiviezo C., Sauter B. V., et al. Caspase-3 and tissue factor expression in lipid-rich plaque macrophages: evidence for apoptosis as link between inflammation and atherothrombosis. Circulation: 2004; 109 16 2001 2008
100. Cirillo P., Golino P., Calabrò P., et al. C-reactive protein induces tissue factor expression and promotes smooth muscle and endothelial cell proliferation. Cardiovasc Res: 2005; 68 1 47 55
101. Cirillo P., Angri V., De Rosa S., et al. Pro-atherothrombotic effects of leptin in human coronary endothelial cells. Thromb Haemost: 2010; 103 5 1065 1075
102. Cirillo P., Ziviello F., Pellegrino G., et al. The adipokine apelin-13 induces expression of prothrombotic tissue factor. Thromb Haemost: 2015; 113 2 363 372