A majority of m6A residues are in the last exons, allowing the potential for 3ʹ UTR regulation

Genes and Development

Volumn 29, Issue 19, 2015, Pages 2037-2053

  Ke, Shengdong ^a   Alemu, Endalkachew A ^b,c,f   Mertens, Claudia ^a,f   Gantman, Emily Conn ^a,d   Fak, John J ^a   Mele, Aldo ^a,g   Haripal, Bhagwattie ^a   Zucker Scharff, Ilana ^a   Moore, Michael J ^a   Park, Christopher Y ^a,d   Vågbø, Cathrine Broberg ^e   Kuśnierczyk, Anna ^e   Klungland, Arne ^b,c   Darnell, James E ^a   Darnell, Robert B ^a,d  

^a ROCKEFELLER UNIVERSITY   (United States)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

^d NEW YORK GENOME CENTER   (United States)

^e NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^f University of Cambridge ^*

^g UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Alternative polyadenylation; Last exon; M6A CLIP IP; microRNA

Indexed keywords

ARGONAUTE PROTEIN; MESSENGER RNA; METHYLTRANSFERASE; NUCLEOTIDE; 3' UNTRANSLATED REGION; ADENOSINE; TRANSFER RNA METHYLTRANSFERASE;

3' UNTRANSLATED REGION; ALTERNATIVE POLYADENYLATION; ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN; CONTROLLED STUDY; CROSS LINKING; CROSS LINKING IMMUNOPRECIPITATION; EXON; GENE CONTROL; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIVER; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; REGULATORY RNA SEQUENCE; RNA METHYLATION; RNA PROCESSING; SINGLE NUCLEOTIDE POLYMORPHISM; STOP CODON; ULTRAVIOLET SPECTROSCOPY; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DNA METHYLATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; MOUSE;

3' UNTRANSLATED REGIONS; ADENOSINE; ANIMALS; BRAIN; CELL LINE; DNA METHYLATION; EXONS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; LIVER; MICE; POLYADENYLATION; RNA, MESSENGER; TRNA METHYLTRANSFERASES;

EID: 84943570207     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.269415.115     Document Type: Article

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