Thioredoxin-1 (Trx1) engineered mesenchymal stem cell therapy increased pro-angiogenic factors, reduced fibrosis and improved heart function in the infarcted rat myocardium

International Journal of Cardiology

Volumn 201, Issue , 2015, Pages 517-528

  Suresh, Sumanth C ^a   Selvaraju, Vaithinathan ^a   Thirunavukkarasu, Mahesh ^a   Goldman, Joshua W ^a   Husain, Aaftab ^a   Palesty, J Alexander ^b   Sanchez, Juan A ^a   McFadden, David W ^a   Maulik, Nilanjana ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b ST MARY S HOSPITAL   (United States)

Author keywords

Angiogenesis; Gene therapy; Mesenchymal stem cells; Myocardial infarction; Thioredoxin 1; VEGF

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENIC FACTOR; BETA GALACTOSIDASE; CHEMOKINE RECEPTOR CXCR4; CONNEXIN 43; HEME OXYGENASE 1; THIOREDOXIN 1; VASCULOTROPIN; THIOREDOXIN; TXN PROTEIN, HUMAN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CELL ASSAY; CELL DIFFERENTIATION; CELL DIVISION; CELL ENGINEERING; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DISEASE MODEL; DNA MODIFICATION; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; GENETIC ENGINEERING; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; IMMUNOHISTOCHEMISTRY; ISCHEMIC PRECONDITIONING; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SHAM PROCEDURE; SMOOTH MUSCLE FIBER; THERAPY EFFECT; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CYTOLOGY; FIBROSIS; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; MYOCARDIAL INFARCTION; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; CELL DIFFERENTIATION; FIBROSIS; GENETIC THERAPY; HEME OXYGENASE-1; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4; THIOREDOXINS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84943549550     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.08.117     Document Type: Article

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