A secreted protein (Canopy 2, CNPY2) enhances angiogenesis and promotes smoothmuscle cell migration and proliferation

Cardiovascular Research

Volumn 105, Issue 3, 2015, Pages 383-393

  Guo, Jian ^a,b   Zhang, Yuemei ^a,b   Mihic, Anton ^a,b   Li, Shu Hong ^a,b   Sun, Zhuo ^a,b   Shao, Zhengbo ^a,b   Wu, Jun ^a,b   Weisel, Richard D ^a,b   Li, Ren Ke ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Angiogenesis; CNPY2; HIF 1 ; Hypoxia; Hypoxia response element; Revascularization

Indexed keywords

CANOPY 2 PROTEIN; FOCAL ADHESION KINASE; GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; P21 ACTIVATED KINASE 1; PROTEIN CDC42; UNCLASSIFIED DRUG; CANOPY 2 PROTEIN, MOUSE; CNPY2 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; MEMBRANE PROTEIN; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANOPY 2 GENE; CARDIOVASCULAR MORTALITY; CELL MIGRATION; CELL POLARITY; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOSKELETON; ENDOPLASMIC RETICULUM; EX VIVO STUDY; GENE; GENE INDUCTION; GENE SILENCING; GOLGI COMPLEX; HEART MUSCLE REVASCULARIZATION; HUMAN; HUMAN CELL; HYPOXIA; HYPOXIA RESPONSIVE ELEMENT; IN VITRO STUDY; ISCHEMIC HEART DISEASE; LUCIFERASE ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN LOCALIZATION; REPERFUSION INJURY; RETINA NEOVASCULARIZATION; SMOOTH MUSCLE CELL; THORACIC AORTIC RING (SLICE); UPREGULATION; ANIMAL; BINDING SITE; BLOOD; CELL HYPOXIA; CELL MOTION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOPHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TIME; VASCULAR SMOOTH MUSCLE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CELL HYPOXIA; CELL MOVEMENT; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PROMOTER REGIONS, GENETIC; RATS; REPERFUSION INJURY; RETINAL NEOVASCULARIZATION; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84943518159     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvv010     Document Type: Article

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