-
1
-
-
56549096891
-
Clinical progress in acute myeloid leukemia
-
Rowe JM. Clinical progress in acute myeloid leukemia. Best Pract Res Clin Haematol 2008; 21: 597-599.
-
(2008)
Best Pract Res Clin Haematol
, vol.21
, pp. 597-599
-
-
Rowe, J.M.1
-
3
-
-
46849122024
-
Molecular characterization of acute myeloid leukemia
-
Dohner K, Dohner H. Molecular characterization of acute myeloid leukemia. Haematologica 2008; 93: 976-982.
-
(2008)
Haematologica
, vol.93
, pp. 976-982
-
-
Dohner, K.1
Dohner, H.2
-
4
-
-
33846635060
-
Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: Recent advances
-
Mrozek K, Dohner H, Bloomfield CD. Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: recent advances. Curr Opin Hematol 2007; 14: 106-114.
-
(2007)
Curr Opin Hematol
, vol.14
, pp. 106-114
-
-
Mrozek, K.1
Dohner, H.2
Bloomfield, C.D.3
-
5
-
-
42949142189
-
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
-
Schlenk RF, Dohner K, Krauter J, et al. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Eng J Med 2008; 358: 1909-1918.
-
(2008)
N Eng J Med
, vol.358
, pp. 1909-1918
-
-
Schlenk, R.F.1
Dohner, K.2
Krauter, J.3
-
6
-
-
0035885955
-
The presence of a FLT3 internal tandem duplication with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
-
Kottaridis PD, Gale RE, Frew ME, et al. The presence of a FLT3 internal tandem duplication with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 2001; 98: 1752-1759.
-
(2001)
Blood
, vol.98
, pp. 1752-1759
-
-
Kottaridis, P.D.1
Gale, R.E.2
Frew, M.E.3
-
7
-
-
0037114829
-
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics
-
Frohling S, Schlenk RF, Breitruck J, et al. Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics. Blood 2002; 100: 4372-4380.
-
(2002)
Blood
, vol.100
, pp. 4372-4380
-
-
Frohling, S.1
Schlenk, R.F.2
Breitruck, J.3
-
8
-
-
0035476264
-
Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
-
Whitman SP, Archer KJ, Feng L, et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. Cancer Res 2001; 61: 7233-7239.
-
(2001)
Cancer Res
, vol.61
, pp. 7233-7239
-
-
Whitman, S.P.1
Archer, K.J.2
Feng, L.3
-
9
-
-
0037097716
-
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous w association with FAB subtypes and identification of subgroups with poor prognosis
-
Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous w association with FAB subtypes and identification of subgroups with poor prognosis. Blood 2002; 99: 4326-4335.
-
(2002)
Blood
, vol.99
, pp. 4326-4335
-
-
Thiede, C.1
Steudel, C.2
Mohr, B.3
-
10
-
-
41949090673
-
The impact of FLT3 internal tandem duplication mutant level, number, size and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
-
Gale RE, Green C, Allen C, et al. The impact of FLT3 internal tandem duplication mutant level, number, size and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia. Blood 2008; 111: 2776-2784.
-
(2008)
Blood
, vol.111
, pp. 2776-2784
-
-
Gale, R.E.1
Green, C.2
Allen, C.3
-
11
-
-
33748467435
-
Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study
-
Paschka P, Marcucci G, Ruppert AS, et al. Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study. J Clin Oncol 2006; 24: 3904-3911.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3904-3911
-
-
Paschka, P.1
Marcucci, G.2
Ruppert, A.S.3
-
12
-
-
33646432204
-
Prognostic impact of c-KIT mutations in core binding factor leukemias: An Italian retrospective study
-
Cairoli R, Beghini A, Grillo G, et al. Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study. Blood 2006; 107: 3463-3468.
-
(2006)
Blood
, vol.107
, pp. 3463-3468
-
-
Cairoli, R.1
Beghini, A.2
Grillo, G.3
-
13
-
-
33344465478
-
KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
-
Schnittiger S, Kohl TM, Haferlach T, et al. KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival. Blood 2006; 107: 1791-1799.
-
(2006)
Blood
, vol.107
, pp. 1791-1799
-
-
Schnittiger, S.1
Kohl, T.M.2
Haferlach, T.3
-
14
-
-
28444446313
-
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML):association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
-
Verhaak RG, Goudswaard CS, van Putten W, et al. Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML):association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood 2005; 106: 3747-3754.
-
(2005)
Blood
, vol.106
, pp. 3747-3754
-
-
Verhaak, R.G.1
Goudswaard, C.S.2
Van Putten, W.3
-
15
-
-
28444473100
-
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics:interaction with other gene mutations
-
Dohner K, Schlenk RF, Habdank M, et al. Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics:interaction with other gene mutations. Blood 2005; 106: 3740-3746.
-
(2005)
Blood
, vol.106
, pp. 3740-3746
-
-
Dohner, K.1
Schlenk, R.F.2
Habdank, M.3
-
16
-
-
77449146413
-
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype respresents a distinct genetic entity associated with a favorable clinical outcome
-
Dufour A, Schneider F, Metzeler KH, et al. Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype respresents a distinct genetic entity associated with a favorable clinical outcome. J Clin Oncol 2010; 28: 570-577.
-
(2010)
J Clin Oncol
, vol.28
, pp. 570-577
-
-
Dufour, A.1
Schneider, F.2
Metzeler, K.H.3
-
17
-
-
63849241865
-
Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favourable outcome
-
Wouters BJ, Lowenberg B, Erpelinck-Verschueren CA, et al. Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favourable outcome. Blood 2009; 113: 3088-3091.
-
(2009)
Blood
, vol.113
, pp. 3088-3091
-
-
Wouters, B.J.1
Lowenberg, B.2
Erpelinck-Verschueren, C.A.3
-
18
-
-
64949122396
-
Heterogeneity within AML with CEBPA mutations; Only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis
-
Pabst T, Eyholzer M, Fos J, et al. Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis. Br J Cancer 2009; 100: 1343-1346.
-
(2009)
Br J Cancer
, vol.100
, pp. 1343-1346
-
-
Pabst, T.1
Eyholzer, M.2
Fos, J.3
-
19
-
-
67149119558
-
The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal tandem duplication
-
Renneville A, Boissel N, Gachard N, et al. The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal tandem duplication. Blood 2009; 113: 5090-5093.
-
(2009)
Blood
, vol.113
, pp. 5090-5093
-
-
Renneville, A.1
Boissel, N.2
Gachard, N.3
-
20
-
-
67349180268
-
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukemia
-
Gallay N, Dos Santos C, Cuzin L, et al. The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukemia. Leukemia 2009; 23: 1029-1038.
-
(2009)
Leukemia
, vol.23
, pp. 1029-1038
-
-
Gallay, N.1
Dos Santos, C.2
Cuzin, L.3
-
21
-
-
0037513474
-
Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia:its significance as a prognostic variable
-
Min YH, Eom JI, Cheong JW, et al. Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia:its significance as a prognostic variable. Leukemia 2003; 17: 995-997.
-
(2003)
Leukemia
, vol.17
, pp. 995-997
-
-
Min, Y.H.1
Eom, J.I.2
Cheong, J.W.3
-
22
-
-
34547932268
-
Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients
-
Tamburini J, Elie C, Bardet V, et al. Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients. Blood 2007; 110: 1025-1028.
-
(2007)
Blood
, vol.110
, pp. 1025-1028
-
-
Tamburini, J.1
Elie, C.2
Bardet, V.3
-
23
-
-
48749108800
-
Deregulation of signaling pathways in acute myeloid leukemia
-
Sholl C, Gilliland DG, Frohling S. Deregulation of signaling pathways in acute myeloid leukemia. Semin Oncol 2008; 35: 336-345.
-
(2008)
Semin Oncol
, vol.35
, pp. 336-345
-
-
Sholl, C.1
Gilliland, D.G.2
Frohling, S.3
-
24
-
-
42449165060
-
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia
-
Steelman LS, Abrams SL, Whelan J, et al. Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. Leukemia 2008; 22: 686-707.
-
(2008)
Leukemia
, vol.22
, pp. 686-707
-
-
Steelman, L.S.1
Abrams, S.L.2
Whelan, J.3
-
25
-
-
0030972025
-
Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells
-
Towatari M, Iida H, Tanimoto M, et al. Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells. Leukemia 1997; 11: 479-484.
-
(1997)
Leukemia
, vol.11
, pp. 479-484
-
-
Towatari, M.1
Iida, H.2
Tanimoto, M.3
-
26
-
-
79960237399
-
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways
-
McCubrey JA, Steelman LS, Kempf CR, et al. Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways. J Cell Physiol 2011; 226: 2762-2781.
-
(2011)
J Cell Physiol
, vol.226
, pp. 2762-2781
-
-
McCubrey, J.A.1
Steelman, L.S.2
Kempf, C.R.3
-
27
-
-
34547209343
-
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007; 1773: 1263-1284.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1263-1284
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
-
28
-
-
42449146501
-
Targeting survival cascades induced by activation of Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy
-
McCubrey JA, Steelman LS, Abrams SL, et al. Targeting survival cascades induced by activation of Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. Leukemia 2008; 22: 708-722.
-
(2008)
Leukemia
, vol.22
, pp. 708-722
-
-
McCubrey, J.A.1
Steelman, L.S.2
Abrams, S.L.3
-
29
-
-
84943395484
-
Putification of the 170-to 180-kilodalton membrane glycoprotein associated with multidrug resistance-170-to 180-kilodalton membrane protein is an ATPase
-
Hamda H, Tsuruo T. Putification of the 170-to 180-kilodalton membrane glycoprotein associated with multidrug resistance-170-to 180-kilodalton membrane protein is an ATPase. J Biol Chem 1998; 263: 1454-1458.
-
(1998)
J Biol Chem
, vol.263
, pp. 1454-1458
-
-
Hamda, H.1
Tsuruo, T.2
-
30
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
Cordon-Cardo C, OBrien JP, Casalas D, et al. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sci USA 1989; 86: 695-698.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
OBrien, J.P.2
Casalas, D.3
-
31
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, et al. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 1987; 84: 7735-7738.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
-
32
-
-
0026465461
-
Expression and activity of the multidrug-resistance P-glycoprotein in human peripheral blood lymphocytes
-
Chaudhary PM, Mechetner EB, Roninson IB. Expression and activity of the multidrug-resistance P-glycoprotein in human peripheral blood lymphocytes. Blood 1992; 80: 2735-2739.
-
(1992)
Blood
, vol.80
, pp. 2735-2739
-
-
Chaudhary, P.M.1
Mechetner, E.B.2
Roninson, I.B.3
-
33
-
-
0025799513
-
Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
-
Chaudhary PM, Roninson IB. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 1991; 66: 85-94.
-
(1991)
Cell
, vol.66
, pp. 85-94
-
-
Chaudhary, P.M.1
Roninson, I.B.2
-
34
-
-
0008819588
-
The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus
-
Arceci RJ, Croop JM, Horowitz SB, et al. The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus. Proc Natl Acad Sci USA 1988; 85: 4350-4354.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4350-4354
-
-
Arceci, R.J.1
Croop, J.M.2
Horowitz, S.B.3
-
35
-
-
0023813001
-
Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells
-
Hamada H, Tsuruo T. Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells. Cancer Res 1988; 48: 4926-4932.
-
(1988)
Cancer Res
, vol.48
, pp. 4926-4932
-
-
Hamada, H.1
Tsuruo, T.2
-
36
-
-
0008632564
-
Expression of a full-length cDNA for the human "mDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
-
Ueda K, Cardarelli C, Gottesman MM, et al. Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc Natl Acad Sci USA 1987; 84: 3004-3008.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 3004-3008
-
-
Ueda, K.1
Cardarelli, C.2
Gottesman, M.M.3
-
38
-
-
0032430818
-
Overexpression of lung-resistance protein and increased P-gp function in acute myeloid leukemia cells predict a poor response to chemotherapy and reduced patient survival
-
Borg AG, Burgess R, Green LM, et al. Overexpression of lung-resistance protein and increased P-gp function in acute myeloid leukemia cells predict a poor response to chemotherapy and reduced patient survival. Br J Haematol 1998; 103: 1083-1091.
-
(1998)
Br J Haematol
, vol.103
, pp. 1083-1091
-
-
Borg, A.G.1
Burgess, R.2
Green, L.M.3
-
39
-
-
9444223257
-
P-glycoprotein expression in patient with acute leukemia-clinical relevance
-
Nussler V, Pelka-Fleischer R, Zwierzina H, et al. P-glycoprotein expression in patient with acute leukemia-clinical relevance. Leukemia 1996; 10 (Suppl. 3): S23-S31.
-
(1996)
Leukemia
, vol.10
, pp. S23-S31
-
-
Nussler, V.1
Pelka-Fleischer, R.2
Zwierzina, H.3
-
40
-
-
0028793942
-
Expression of multidrug resistance associated protein (MRP) and multidrug resistance (MDR1) genes in acute myeloid leukemia
-
Zhou DC, Zittoun R, Marie JP. Expression of multidrug resistance associated protein (MRP) and multidrug resistance (MDR1) genes in acute myeloid leukemia. Leukemia 1995; 9: 1661-1666.
-
(1995)
Leukemia
, vol.9
, pp. 1661-1666
-
-
Zhou, D.C.1
Zittoun, R.2
Marie, J.P.3
-
41
-
-
33847225602
-
Multidrug resistance-associated protein 1 expression is under the control of phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts
-
Tazzari PL, Capellini A, Ricci F, et al. Multidrug resistance-associated protein 1 expression is under the control of phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts. Leukemia 2007; 21: 427-438.
-
(2007)
Leukemia
, vol.21
, pp. 427-438
-
-
Tazzari, P.L.1
Capellini, A.2
Ricci, F.3
-
42
-
-
84897018280
-
High-dose cytarabine in induction treatment improves the outcome of adult patients younger than age 46 years with acute myeloid leukemia: Results of the EORTC-GIMEMA AML-12 trial
-
Willemze R, Suciu S, Meloni G, et al. High-dose cytarabine in induction treatment improves the outcome of adult patients younger than age 46 years with acute myeloid leukemia: results of the EORTC-GIMEMA AML-12 trial. J Clin Oncol 2014; 32: 219-228.
-
(2014)
J Clin Oncol
, vol.32
, pp. 219-228
-
-
Willemze, R.1
Suciu, S.2
Meloni, G.3
-
43
-
-
84879409297
-
Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and daunorubicin in the treatment of nonelderly APL patients
-
Adès L, Chevret S, Raffoux E, et al.; European APL group. Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and daunorubicin in the treatment of nonelderly APL patients. Am J Hematol 2013; 88: 556-559.
-
(2013)
Am J Hematol
, vol.88
, pp. 556-559
-
-
Adès, L.1
Chevret, S.2
Raffoux, E.3
-
44
-
-
0023115914
-
High-dose cytosine arabinoside and mitoxantrone: A highly effective regimen in w acute myeloid leukemia
-
Hiddemann W, Kreutzmann H, Straif K, et al. High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in w acute myeloid leukemia. Blood 1987; 69: 744-749.
-
(1987)
Blood
, vol.69
, pp. 744-749
-
-
Hiddemann, W.1
Kreutzmann, H.2
Straif, K.3
-
45
-
-
0032534883
-
Reference method for detection of Pgp mediated multidrug resistance in human hematological malignancies: A method validated by laboratories of the French Drug Resistance Network
-
Huet S, Marie JP, Gualde N, et al. Reference method for detection of Pgp mediated multidrug resistance in human hematological malignancies: a method validated by laboratories of the French Drug Resistance Network. Cytometry 1998; 34: 248-256.
-
(1998)
Cytometry
, vol.34
, pp. 248-256
-
-
Huet, S.1
Marie, J.P.2
Gualde, N.3
-
46
-
-
0030874188
-
Flow cytometric analysis of P-glycoprotein function using Rhodamine 123
-
Petriz J, Garcia-Lopez J. Flow cytometric analysis of P-glycoprotein function using Rhodamine 123. Leukemia 1997; 11: 1124-1130.
-
(1997)
Leukemia
, vol.11
, pp. 1124-1130
-
-
Petriz, J.1
Garcia-Lopez, J.2
-
47
-
-
84943375161
-
-
Available from: www.bdbiosciences.com/documents/Phosflow-Protocol-for-Human-PBMCs.pdf
-
-
-
-
48
-
-
0346244001
-
Intracellular phospho-protein staining techniques for flow cytometry: Monitoring single cell signaling events
-
Krutzik PO, Nolan GP. Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry A 2003; 55: 61-70.
-
(2003)
Cytometry A
, vol.55
, pp. 61-70
-
-
Krutzik, P.O.1
Nolan, G.P.2
-
49
-
-
1642463417
-
Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications
-
Krutzik PO, Irish JM, Nolan GP, et al. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Clin Immunol 2004; 110: 206-221.
-
(2004)
Clin Immunol
, vol.110
, pp. 206-221
-
-
Krutzik, P.O.1
Irish, J.M.2
Nolan, G.P.3
-
50
-
-
33745755905
-
Single cell analysis of phosphoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry
-
Bardet V, Tamburini J, Ifrah N, et al. Single cell analysis of phosphoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry. Haematologica 2006; 91: 757-764.
-
(2006)
Haematologica
, vol.91
, pp. 757-764
-
-
Bardet, V.1
Tamburini, J.2
Ifrah, N.3
-
51
-
-
0015246254
-
A rapid banding technique for human chromosomes
-
Seabright M. A rapid banding technique for human chromosomes. Lancet 1971; 2: 971-972.
-
(1971)
Lancet
, vol.2
, pp. 971-972
-
-
Seabright, M.1
-
52
-
-
0033794572
-
Fluorescence in situ hybridizations: Uses and limitations
-
Gozzeti A, Le Beau MM. Fluorescence in situ hybridizations: uses and limitations. Semin Hematol 2000; 37: 320-333.
-
(2000)
Semin Hematol
, vol.37
, pp. 320-333
-
-
Gozzeti, A.1
Le Beau, M.M.2
-
54
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
Nakao M, Yokota S, Iwai T, et al. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia 1996; 10: 1911-1918.
-
(1996)
Leukemia
, vol.10
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
-
55
-
-
0013102483
-
The abuse of power: The pervasive fallacy of power calculations for data analysis
-
Hoeing JM, Heisey DM. The abuse of power: the pervasive fallacy of power calculations for data analysis. Am Stat 2001; 55: 1-6.
-
(2001)
Am Stat
, vol.55
, pp. 1-6
-
-
Hoeing, J.M.1
Heisey, D.M.2
-
56
-
-
0034043234
-
P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy
-
Broxterman HJ, Sonneveld P, van Putten WJ, et al. P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy. Leukemia 2000; 14: 1018-1024.
-
(2000)
Leukemia
, vol.14
, pp. 1018-1024
-
-
Broxterman, H.J.1
Sonneveld, P.2
Van Putten, W.J.3
-
57
-
-
4644367050
-
Activation of Raf1 and the ERK pathway in response to L-ascorbic acid in acute myeloid leukemia cells
-
Park S, Park CH, Hahm ER, et al. Activation of Raf1 and the ERK pathway in response to L-ascorbic acid in acute myeloid leukemia cells. Cell Signal 2005; 17: 111-119.
-
(2005)
Cell Signal
, vol.17
, pp. 111-119
-
-
Park, S.1
Park, C.H.2
Hahm, E.R.3
-
58
-
-
84879382833
-
MEK/ERK dependent activation of STAT1 mediates dasatinib-induced differentiation of acute myeloid leukemia
-
Fang Y, Zhong L, Lin M, et al. MEK/ERK dependent activation of STAT1 mediates dasatinib-induced differentiation of acute myeloid leukemia. PLoS One 2013; 8: e66915.
-
(2013)
PLoS One
, vol.8
, pp. e66915
-
-
Fang, Y.1
Zhong, L.2
Lin, M.3
-
59
-
-
21744453318
-
ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis
-
Svensson S, Jirstrom K, Ryden L, et al. ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. Oncogene 2005; 24: 4370-4379.
-
(2005)
Oncogene
, vol.24
, pp. 4370-4379
-
-
Svensson, S.1
Jirstrom, K.2
Ryden, L.3
-
60
-
-
84876945664
-
Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation
-
Deschenes-Simard X, Gaumont-Leclerc MF, Bourdeau V, et al. Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation. Genes Dev 2013; 27: 900-915.
-
(2013)
Genes Dev
, vol.27
, pp. 900-915
-
-
Deschenes-Simard, X.1
Gaumont-Leclerc, M.F.2
Bourdeau, V.3
-
61
-
-
33748923798
-
Opposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancy
-
Ranganathan AC, Adam AP, Aguirre-Ghiso JA. Opposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancy. Cell Cycle 2006; 5: 1799-1807.
-
(2006)
Cell Cycle
, vol.5
, pp. 1799-1807
-
-
Ranganathan, A.C.1
Adam, A.P.2
Aguirre-Ghiso, J.A.3
-
62
-
-
27544443219
-
Modulation of mitogen-activated protein kinase cascades by differentiation-1 protein: Acquired drug resistance of hormone independent prostate cancer cells
-
Lin JC, Chang SY, Hsien DS, et al. Modulation of mitogen-activated protein kinase cascades by differentiation-1 protein: acquired drug resistance of hormone independent prostate cancer cells. J Urol 2005; 174: 2022-2026.
-
(2005)
J Urol
, vol.174
, pp. 2022-2026
-
-
Lin, J.C.1
Chang, S.Y.2
Hsien, D.S.3
-
63
-
-
84890447356
-
Role of p38 MAP kinase signal transduction in solid tumors
-
Koul HK, Pal M, Koul S. Role of p38 MAP kinase signal transduction in solid tumors. Genes Cancer 2013; 4: 342-359.
-
(2013)
Genes Cancer
, vol.4
, pp. 342-359
-
-
Koul, H.K.1
Pal, M.2
Koul, S.3
-
64
-
-
7644223136
-
P38 MAP kinase's emerging role as a tumor suppressor
-
Bulavin DV, Fornace AJ Jr. P38 MAP kinase's emerging role as a tumor suppressor. Adv Cancer Res 2004; 92: 95-118.
-
(2004)
Adv Cancer Res
, vol.92
, pp. 95-118
-
-
Bulavin, D.V.1
Fornace, A.J.2
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