Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid

Neuropharmacology

Volumn 99, Issue , 2015, Pages 705-714

  De Luca, M A ^a,b   Bimpisidis, Z ^a   Melis, M ^a   Marti, M ^b,c   Caboni, P ^a   Valentini, V ^a,b,g   Margiani, G ^a   Pintori, N ^a   Polis, I ^d   Marsicano, G ^e   Parsons, L H ^d   Di Chiara, G ^a,b,f,g  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b National Institute of Neuroscience   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e UNIVERSITÉ DE BORDEAUX   (France)

^f CNR Institute of Neuroscience   (Italy)

^g Centre of Excellence Neurobiology of Addiction   (Italy)

Author keywords

CB1 receptor; Dopamine; Electrophysiology; JWH 018; Microdialysis; Nucleus accumbens

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 3 (1 NAPHTHOYL) 1 PENTYLINDOLE; 4 AMINOBUTYRIC ACID A RECEPTOR; CANNABINOID 1 RECEPTOR; RIMONABANT; 1-PENTYL-3-(1-NAPHTHOYL)INDOLE; CANNABINOID RECEPTOR AGONIST; CNR1 PROTEIN, MOUSE; DOPAMINE; INDOLE DERIVATIVE; NAPHTHALENE DERIVATIVE;

AMBIGUUS NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CATALEPSY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; DOSE RESPONSE; DRUG ACTIVITY; DRUG ANTAGONISM; EXCITATORY POSTSYNAPTIC POTENTIAL; HOMOZYGOSITY; IN VIVO STUDY; MALE; MEDIAL PREFRONTAL CORTEX; MICRODIALYSIS; MOTOR ACTIVITY; MOUSE; NERVE STIMULATION; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; VENTRAL TEGMENTUM; WHOLE CELL PATCH CLAMP; AGONISTS; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; DRUG EFFECTS; DRUG SELF ADMINISTRATION; GENETICS; INHIBITORY POSTSYNAPTIC POTENTIAL; INTRAVENOUS DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; NUCLEUS ACCUMBENS; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PREFRONTAL CORTEX; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT; TISSUE CULTURE TECHNIQUE;

ADMINISTRATION, INTRAVENOUS; ANIMALS; CANNABINOID RECEPTOR AGONISTS; DOPAMINE; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRODIALYSIS; NAPHTHALENES; NUCLEUS ACCUMBENS; PATCH-CLAMP TECHNIQUES; PREFRONTAL CORTEX; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RECEPTORS, GABA-A; SELF ADMINISTRATION; SPECIES SPECIFICITY; TISSUE CULTURE TECHNIQUES; VENTRAL TEGMENTAL AREA;

EID: 84943380191     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.08.041     Document Type: Article

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