Short-term withdrawal from developmental exposure to cocaine activates the glucocorticoid receptor and alters spine dynamics

European Neuropsychopharmacology

Volumn 25, Issue 10, 2015, Pages 1832-1841

  Caffino, Lucia ^a   Giannotti, Giuseppe ^a   Malpighi, Chiara ^a   Racagni, Giorgio ^a   Fumagalli, Fabio ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Adolescence; Cocaine; Dendritic spine morphology; Glucocorticoid receptor; Prefrontal cortex

Indexed keywords

CHAPERONE; COCAINE; CORTICOSTERONE; FK 506 BINDING PROTEIN; FK506 BINDING PROTEIN 51; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG; DOPAMINE UPTAKE INHIBITOR; TACROLIMUS BINDING PROTEIN 5;

ACTIN FILAMENT; ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CYTOPLASM; CYTOSOL; DENDRITIC SPINE; DRUG WITHDRAWAL; GENE EXPRESSION; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; MALE; MEDIAL PREFRONTAL CORTEX; NONHUMAN; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA TRANSLATION; ANIMAL; BLOOD; DISEASE MODEL; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; SPRAGUE DAWLEY RAT; TIME FACTOR; WITHDRAWAL SYNDROME;

ANIMALS; COCAINE; CORTICOSTERONE; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; DOPAMINE UPTAKE INHIBITORS; MALE; PREFRONTAL CORTEX; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; SUBSTANCE WITHDRAWAL SYNDROME; TACROLIMUS BINDING PROTEINS; TIME FACTORS;

EID: 84943352794     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2015.05.002     Document Type: Article

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