Gene therapy for MERTK-associated retinal degenerations

Advances in Experimental Medicine and Biology

Volumn 854, Issue , 2016, Pages 487-493

  Lavail, Matthew M ^a   Yasumura, Douglas ^a   Matthes, Michael T ^a   Yang, Haidong ^a   Hauswirth, William W ^b   Deng, Wen Tao ^b   Vollrath, Douglas ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene therapy; MERTK; Phagocytosis; Retinal degeneration; Treatment

Indexed keywords

ADENOVIRUS VECTOR; AGENTS ACTING ON THE EYE; MERTK PROTEIN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; BEST1 PROTEIN, HUMAN; CHLORIDE CHANNEL; EYE PROTEIN; MERTK PROTEIN, HUMAN; MERTK PROTEIN, MOUSE; MERTK PROTEIN, RAT; ONCOPROTEIN;

A WAVE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; B WAVE; CONTROLLED STUDY; DRUG EFFICACY; ELECTRIC ACTIVITY; MERTK GENE; NONHUMAN; PHAGOCYTOSIS; PHOTORECEPTOR; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; SUBRETINAL DRUG ADMINISTRATION; TREATMENT RESPONSE; VIRAL GENE THERAPY; ANIMAL; DEFICIENCY; DEPENDOPARVOVIRUS; DISEASE MODEL; ELECTRORETINOGRAPHY; GENE THERAPY; GENE VECTOR; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MUTANT RAT STRAIN; PATHOPHYSIOLOGY; PHAGOSOME; PHYSIOLOGY; PROCEDURES; PROMOTER REGION; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; CHLORIDE CHANNELS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; EYE PROTEINS; GENETIC THERAPY; GENETIC VECTORS; HUMANS; MICE, KNOCKOUT; PHAGOCYTOSIS; PHAGOSOMES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM; TREATMENT OUTCOME;

EID: 84943339769     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-17121-0_65     Document Type: Chapter

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