Hypoionic shock treatment enables aminoglycosides antibiotics to eradicate bacterial persisters

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Jiafeng, Liu ^a   Fu, Xinmiao ^a   Chang, Zengyi ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; OSMOTIC PRESSURE; PHYSIOLOGY; PROTON MOTIVE FORCE; STAPHYLOCOCCUS AUREUS;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; MICROBIAL SENSITIVITY TESTS; OSMOTIC PRESSURE; PROTON-MOTIVE FORCE; STAPHYLOCOCCUS AUREUS;

EID: 84943311290     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep14247     Document Type: Article

References (35)

1. Bush, K. et al. Tackling antibiotic resistance. Nat. Rev. Micro. 9, 894-896 (2011).
2. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations. Review on Antimicrobial Resistance. (2014) Available at: http://amr-review.org/(Accessed: 11 December 2014)
3. Antimicrobial resistance Global Report on Surveillance. WHO. (2014) Available at: http://www.who.int/drugresistance/documents/surveillancereport/en/(Accessed: April 2014)
4. Antibiotic resistance threats in the united states. CDC. (2013) Available at: http://www.cdc.gov/drugresistance/threat-report-2013/(Accessed: 17 July 2014)
5. Alekshun, M. N., Levy, S. B. Molecular Mechanisms of Antibacterial Multidrug Resistance. Cell 128, 1037-1050 (2007).
6. Toprak, E. et al. Evolutionary paths to antibiotic resistance under dynamically sustained drug selection. Nat Genet 44, 101-105 (2012).
7. Bigger, J. Treatment of staphylococcal infections with penicillin by intermittent sterilisation. Lancet 244, 497-500 (1944).
8. Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L., Leibler, S. Bacterial persistence as a phenotypic switch. Science 305, 1622-1625 (2004).
9. Lewis, K. Persister cells. Annu. Rev. Microbiol. 64, 357-72 (2010).
10. Maisonneuve, E., Gerdes, K. Molecular mechanisms underlying bacterial persisters. Cell 157, 539-548 (2014).
11. Allison, K. R., Brynildsen, M. P., Collins, J. J. Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 473, 216-20 (2011).
12. Fridman, O., Goldberg, A., Ronin, I., Shoresh, N., Balaban, N. Q. Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations. Nature 513, 418-421 (2014).
13. Levin, B. R., Rozen, D. E. Non-inherited antibiotic resistance. Nat. Rev. Microbiol. 4, 556-562 (2006).
14. Smith, P. A., Romesberg, F. E. Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation. Nat Chem Biol 3, 549-556 (2007).
15. Davis, B. D. Mechanism of bactericidal action of aminoglycosides. Microbiol. Rev. 51, 341-50 (1987).
16. Magnet, S., Blanchard, J. S. Molecular insights into aminoglycoside action and resistance. Chem. Rev. 105, 477-98 (2005).
17. Conlon, B. P. et al. Activated ClpP kills persisters and eradicates a chronic biofilm infection. Nature 503, 365-70 (2013).
18. Lebeaux, D. et al. pH-Mediated Potentiation of Aminoglycosides Kills Bacterial Persisters and Eradicates In Vivo Biofilms. J. Infect. Dis. 210, 1357-1366 (2014).
19. Lim, J. Y., May, J. M., Cegelski, L. Dimethyl Sulfoxide and Ethanol Elicit Increased Amyloid Biogenesis and Amyloid-Integrated Biofilm Formation in Escherichia coli. Appl. Environ. Microbiol. 78, 3369-3378 (2012).
20. Reiner, A. M. Genes for ribitol and D-arabitol catabolism in Escherichia coli: their loci in C strains and absence in K-12 and B strains. J. Bacteriol. 123, 530-536 (1975).
21. Casadaban, M. J. Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. J. Mol. Biol. 104, 541-555 (1976).
22. Plotz, P. H., DUBIN, D. T., DAVIS, B. D. Influence of Salts on the Uptake of Streptomycin by Escherichia coli. Nature 191, 1324-1325 (1961).
23. Nichols, W. W., Young, S. N. Respiration-dependent uptake of dihydrostreptomycin by Escherichia coli. Its irreversible nature and lack of evidence for a uniport process. Biochem. J. 228, 505-512 (1985).
24. Kung, C., Martinac, B., Sukharev, S. Mechanosensitive channels in microbes. Annu. Rev. Microbiol. 64, 313-29 (2010).
25. Wood, J. M. Bacterial osmoregulation: a paradigm for the study of cellular homeostasis. Annu. Rev. Microbiol. 65, 215-38 (2011).
26. Levina, N. et al. Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity. EMBO J. 18, 1730-1737 (1999).
27. Iscla, I., Wray, R., Wei, S., Posner, B., Blount, P. Streptomycin potency is dependent on MscL channel expression. Nat. Commun. 5, 4891 (2014).
28. Naismith, J. H., Booth, I. R. Bacterial mechanosensitive channels-MscS: evolution's solution to creating sensitivity in function. Annu. Rev. Biophys. 41, 157-77 (2012).
29. Cruickshank, C. C., Minchin, R. F., Le Dain, A. C., Martinac, B. Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli. Biophys. J. 73, 1925-1931 (1997).
30. Sukharev, S. I., Blount, P., Martinac, B., Blattner, F. R., Kung, C. A large-conductance mechanosensitive channel in E. coli encoded by mscL alone. Nature 368, 265-268 (1994).
31. Bialecka-Fornal, M., Lee, H. J., Phillips, R. The rate of osmotic downshock determines the survival probability of bacterial mechanosensitive channel mutants. J. Bacteriol. 197, 231-7 (2015).
32. Dijkstra, A. J., Keck, W. Peptidoglycan as a barrier to transenvelope transport. J. Bacteriol. 178, 5555-5562 (1996).
33. Whatmore, A. M., Reed, R. H. Determination of turgor pressure in Bacillus subtilis: a possible role for K+ in turgor regulation. J. Gen. Microbiol. 136, 2521-2526 (1990).
34. Haynes, W. J. et al. Indole and other aromatic compounds activate the yeast TRPY1 channel. FEBS Lett. 582, 1514-1518 (2008).
35. Nguyen, T., Clare, B., Guo, W., Martinac, B. The effects of parabens on the mechanosensitive channels of E. coli. Eur. Biophys. J. 34, 389-395 (2005).