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Volumn 3, Issue 9, 2007, Pages 549-556

Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPICILLIN; BETA LACTAM ANTIBIOTIC; CIPROFLOXACIN; METICILLIN; NORFLOXACIN; PSEUDOMONIC ACID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; SHIGA TOXIN; TETRACYCLINE; VANCOMYCIN;

EID: 34548094623     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.2007.27     Document Type: Review
Times cited : (170)

References (99)
  • 1
    • 0036232890 scopus 로고    scopus 로고
    • Antimicrobial use and antimicrobial resistance: A population perspective
    • Lipsitch, M. & Samore, M.H. Antimicrobial use and antimicrobial resistance: a population perspective. Emerg. Infect. Dis. 8, 347-354 (2002).
    • (2002) Emerg. Infect. Dis , vol.8 , pp. 347-354
    • Lipsitch, M.1    Samore, M.H.2
  • 2
    • 33745247409 scopus 로고    scopus 로고
    • Antimicrobial resistance in gram-positive bacteria
    • discussion S64-73
    • Rice, L.B. Antimicrobial resistance in gram-positive bacteria. Am. J. Infect. Control 34 (suppl. 1), S11-19; discussion S64-73 (2006).
    • (2006) Am. J. Infect. Control , vol.34 , Issue.SUPPL. 1
    • Rice, L.B.1
  • 3
    • 33645119729 scopus 로고    scopus 로고
    • Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs - worldwide, 2000-2004
    • Wright, A. et al. Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs - worldwide, 2000-2004. MMWR Morb. Mortal. Wkly. Rep. 55, 301-305 (2006).
    • (2006) MMWR Morb. Mortal. Wkly. Rep , vol.55 , pp. 301-305
    • Wright, A.1
  • 4
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial discovery
    • Payne, D.J., Gwynn, M.N., Holmes, D.J. & Pompliano, D.L. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6, 29-40 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 5
    • 33144473431 scopus 로고    scopus 로고
    • Bad bugs need drugs: An update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America
    • Talbot, G.H. et al. Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin. Infect. Dis. 42, 657-668 (2006).
    • (2006) Clin. Infect. Dis , vol.42 , pp. 657-668
    • Talbot, G.H.1
  • 6
    • 0023749808 scopus 로고
    • Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance
    • Jin, D.J. & Gross, C.A. Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance. J. Mol. Biol. 202, 45-58 (1988).
    • (1988) J. Mol. Biol , vol.202 , pp. 45-58
    • Jin, D.J.1    Gross, C.A.2
  • 7
    • 0031407768 scopus 로고    scopus 로고
    • DNA gyrase, topoisomerase IV, and the 4-quinolones
    • Drlica, K. & Zhao, X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol. Mol. Biol. Rev. 61, 377-392 (1997).
    • (1997) Microbiol. Mol. Biol. Rev , vol.61 , pp. 377-392
    • Drlica, K.1    Zhao, X.2
  • 8
    • 0027941783 scopus 로고
    • Molecular genetics of drug resistance in Mycobacterium tuberculosis
    • Zhang, Y. & Young, D. Molecular genetics of drug resistance in Mycobacterium tuberculosis. J. Antimicrob. Chemother. 34, 313-319 (1994).
    • (1994) J. Antimicrob. Chemother , vol.34 , pp. 313-319
    • Zhang, Y.1    Young, D.2
  • 9
    • 33845321413 scopus 로고    scopus 로고
    • The emergence of antibiotic resistance by mutation
    • Woodford, N. & Ellington, M.J. The emergence of antibiotic resistance by mutation. Clin. Microbiol. Infect. 13, 5-18 (2007).
    • (2007) Clin. Microbiol. Infect , vol.13 , pp. 5-18
    • Woodford, N.1    Ellington, M.J.2
  • 10
    • 0029843192 scopus 로고    scopus 로고
    • Spontaneous mutators in bacteria: Insights into pathways of mutagenesis and repair
    • Miller, J.H. Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair. Annu. Rev. Microbiol. 50, 625-643 (1996).
    • (1996) Annu. Rev. Microbiol , vol.50 , pp. 625-643
    • Miller, J.H.1
  • 11
    • 29944445616 scopus 로고    scopus 로고
    • Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria
    • Cirz, R.T. & Romesberg, F.E. Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria. Antimicrob. Agents Chemother. 50, 220-225 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 220-225
    • Cirz, R.T.1    Romesberg, F.E.2
  • 12
    • 0029860724 scopus 로고    scopus 로고
    • High mutation frequencies among Escherichia coli and Salmonella pathogens
    • LeClerc, J.E., Li, B., Payne, W.L. & Cebula, T.A. High mutation frequencies among Escherichia coli and Salmonella pathogens. Science 274, 1208-1211 (1996).
    • (1996) Science , vol.274 , pp. 1208-1211
    • LeClerc, J.E.1    Li, B.2    Payne, W.L.3    Cebula, T.A.4
  • 13
    • 0034685940 scopus 로고    scopus 로고
    • High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection
    • Oliver, A., Canton, R., Campo, P., Baquero, F. & Blazquez, J. High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. Science 288, 1251-1254 (2000).
    • (2000) Science , vol.288 , pp. 1251-1254
    • Oliver, A.1    Canton, R.2    Campo, P.3    Baquero, F.4    Blazquez, J.5
  • 14
    • 34249063087 scopus 로고    scopus 로고
    • Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis
    • Montanari, S. et al. Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis. Microbiology 153, 1445-1454 (2007).
    • (2007) Microbiology , vol.153 , pp. 1445-1454
    • Montanari, S.1
  • 15
    • 0034049514 scopus 로고    scopus 로고
    • The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness
    • Funchain, P. et al. The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness. Genetics 154, 959-970 (2000).
    • (2000) Genetics , vol.154 , pp. 959-970
    • Funchain, P.1
  • 16
    • 0035970874 scopus 로고    scopus 로고
    • Costs and benefits of high mutation rates: Adaptive evolution of bacteria in the mouse gut
    • Giraud, A. et al. Costs and benefits of high mutation rates: adaptive evolution of bacteria in the mouse gut. Science 291, 2606-2608 (2001).
    • (2001) Science , vol.291 , pp. 2606-2608
    • Giraud, A.1
  • 17
  • 18
    • 0026094779 scopus 로고
    • Adaptive reversion of a frameshift mutation in Escherichia coli
    • Cairns, J. & Foster, P.L. Adaptive reversion of a frameshift mutation in Escherichia coli. Genetics 128, 695-701 (1991).
    • (1991) Genetics , vol.128 , pp. 695-701
    • Cairns, J.1    Foster, P.L.2
  • 19
    • 0030051842 scopus 로고    scopus 로고
    • Two enzymes, both of which process recombination intermediates, have opposite effects on adaptive mutation in Escherichia coli
    • Foster, P.L., Trimarchi, J.M. & Maurer, R.A. Two enzymes, both of which process recombination intermediates, have opposite effects on adaptive mutation in Escherichia coli. Genetics 142, 25-37 (1996).
    • (1996) Genetics , vol.142 , pp. 25-37
    • Foster, P.L.1    Trimarchi, J.M.2    Maurer, R.A.3
  • 20
    • 0030000945 scopus 로고    scopus 로고
    • Opposing roles of the holliday junction processing systems of Escherichia coli in recombination-dependent adaptive mutation
    • Harris, R.S., Ross, K.J. & Rosenberg, S.M. Opposing roles of the holliday junction processing systems of Escherichia coli in recombination-dependent adaptive mutation. Genetics 142, 681-691 (1996).
    • (1996) Genetics , vol.142 , pp. 681-691
    • Harris, R.S.1    Ross, K.J.2    Rosenberg, S.M.3
  • 21
    • 0031746001 scopus 로고    scopus 로고
    • Recombination- dependent mutation in Escherichia coli occurs in stationary phase
    • McKenzie, G.J., Lombardo, M.J. & Rosenberg, S.M. Recombination- dependent mutation in Escherichia coli occurs in stationary phase. Genetics 149, 1163-1165 (1998).
    • (1998) Genetics , vol.149 , pp. 1163-1165
    • McKenzie, G.J.1    Lombardo, M.J.2    Rosenberg, S.M.3
  • 23
    • 21344460325 scopus 로고    scopus 로고
    • Inhibition of mutation and combating the evolution of antibiotic resistance
    • Cirz, R.T. et al. Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol. 3, e176 (2005).
    • (2005) PLoS Biol , vol.3
    • Cirz, R.T.1
  • 24
    • 4644351908 scopus 로고    scopus 로고
    • SOS response induction by beta-lactams and bacterial defense against antibiotic lethality
    • Miller, C. et al. SOS response induction by beta-lactams and bacterial defense against antibiotic lethality. Science 305, 1629-1631 (2004).
    • (2004) Science , vol.305 , pp. 1629-1631
    • Miller, C.1
  • 26
    • 0032860807 scopus 로고    scopus 로고
    • Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa
    • Alonso, A., Campanario, E. & Martinez, J.L. Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa. Microbiology 145, 2857-2862 (1999).
    • (1999) Microbiology , vol.145 , pp. 2857-2862
    • Alonso, A.1    Campanario, E.2    Martinez, J.L.3
  • 27
    • 0037453719 scopus 로고    scopus 로고
    • DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis
    • Boshoff, H.I., Reed, M.B., Barry, C.E. III & Mizrahi, V. DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis. Cell 113, 183-193 (2003).
    • (2003) Cell , vol.113 , pp. 183-193
    • Boshoff, H.I.1    Reed, M.B.2    Barry III, C.E.3    Mizrahi, V.4
  • 28
    • 0030620272 scopus 로고    scopus 로고
    • Role of mutator alleles in adaptive evolution
    • Taddei, F. et al. Role of mutator alleles in adaptive evolution. Nature 387, 700-702 (1997).
    • (1997) Nature , vol.387 , pp. 700-702
    • Taddei, F.1
  • 29
    • 34248396718 scopus 로고    scopus 로고
    • Error-prone DNA repair system in enteroaggregative Escherichia coli identified by subtractive hybridization
    • Joo, L.M., Macfarlane-Smith, L.R. & Okeke, I.N. Error-prone DNA repair system in enteroaggregative Escherichia coli identified by subtractive hybridization. J. Bacteriol. 189, 3793-3803 (2007).
    • (2007) J. Bacteriol , vol.189 , pp. 3793-3803
    • Joo, L.M.1    Macfarlane-Smith, L.R.2    Okeke, I.N.3
  • 30
    • 0028224640 scopus 로고
    • Effect of 2′,3′-didehydro-3′-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies
    • Bilello, J.A., Bauer, G., Dudley, M.N., Cole, G.A. & Drusano, G.L. Effect of 2′,3′-didehydro-3′-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies. Antimicrob. Agents Chemother. 38, 1386-1391 (1994).
    • (1994) Antimicrob. Agents Chemother , vol.38 , pp. 1386-1391
    • Bilello, J.A.1    Bauer, G.2    Dudley, M.N.3    Cole, G.A.4    Drusano, G.L.5
  • 31
    • 27144490073 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases: A clinical update
    • Paterson, D.L. & Bonomo, R.A. Extended-spectrum beta-lactamases: a clinical update. Clin. Microbiol. Rev. 18, 657-686 (2005).
    • (2005) Clin. Microbiol. Rev , vol.18 , pp. 657-686
    • Paterson, D.L.1    Bonomo, R.A.2
  • 32
    • 0344827209 scopus 로고    scopus 로고
    • Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus
    • Weigel, L.M. et al. Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus. Science 302, 1569-1571 (2003).
    • (2003) Science , vol.302 , pp. 1569-1571
    • Weigel, L.M.1
  • 33
    • 34248563765 scopus 로고    scopus 로고
    • Evaluation of the AdvanDx VRE EVIGENE assay for detection of vanA in vancomycin-resistant Staphylococcus aureus
    • Fosheim, G.E., Carey, R.B. & Limbago, B.M. Evaluation of the AdvanDx VRE EVIGENE assay for detection of vanA in vancomycin-resistant Staphylococcus aureus. J. Clin. Microbiol. 45, 1611-1613 (2007).
    • (2007) J. Clin. Microbiol , vol.45 , pp. 1611-1613
    • Fosheim, G.E.1    Carey, R.B.2    Limbago, B.M.3
  • 34
    • 0035217633 scopus 로고    scopus 로고
    • Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: Organismal distribution, structural constraints and evolutionary conclusions
    • Cao, T.B. & Saier, M.H. Jr. Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions. Microbiology 147, 3201-3214 (2001).
    • (2001) Microbiology , vol.147 , pp. 3201-3214
    • Cao, T.B.1    Saier Jr., M.H.2
  • 35
    • 2442682800 scopus 로고    scopus 로고
    • Definition of a bacterial type IV secretion pathway for a DNA substrate
    • Cascales, E. & Christie, P.J. Definition of a bacterial type IV secretion pathway for a DNA substrate. Science 304, 1170-1173 (2004).
    • (2004) Science , vol.304 , pp. 1170-1173
    • Cascales, E.1    Christie, P.J.2
  • 36
    • 1642415666 scopus 로고    scopus 로고
    • Unveiling molecular scaffolds of the type IV secretion system
    • Yeo, H.J. & Waksman, G. Unveiling molecular scaffolds of the type IV secretion system. J. Bacteriol. 186, 1919-1926 (2004).
    • (2004) J. Bacteriol , vol.186 , pp. 1919-1926
    • Yeo, H.J.1    Waksman, G.2
  • 38
    • 33749593502 scopus 로고    scopus 로고
    • Inhibitors of Helicobacter pylori ATPase Cagα block CagA transport and cag virulence
    • Hilleringmann, M. et al. Inhibitors of Helicobacter pylori ATPase Cagα block CagA transport and cag virulence. Microbiology 152, 2919-2930 (2006).
    • (2006) Microbiology , vol.152 , pp. 2919-2930
    • Hilleringmann, M.1
  • 39
    • 0034042694 scopus 로고    scopus 로고
    • Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus
    • Backert, S. et al. Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. Cell. Microbiol. 2, 155-164 (2000).
    • (2000) Cell. Microbiol , vol.2 , pp. 155-164
    • Backert, S.1
  • 40
    • 17344379177 scopus 로고    scopus 로고
    • Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion
    • Odenbreit, S. et al. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 287, 1497-1500 (2000).
    • (2000) Science , vol.287 , pp. 1497-1500
    • Odenbreit, S.1
  • 41
    • 0037905748 scopus 로고    scopus 로고
    • Conjugative plasmid transfer in gram-positive bacteria
    • Grohmann, E., Muth, G. & Espinosa, M. Conjugative plasmid transfer in gram-positive bacteria. Microbiol. Mol. Biol. Rev. 67, 277-301 (2003).
    • (2003) Microbiol. Mol. Biol. Rev , vol.67 , pp. 277-301
    • Grohmann, E.1    Muth, G.2    Espinosa, M.3
  • 42
    • 3042596928 scopus 로고    scopus 로고
    • DNA uptake during bacterial transformation
    • Chen, I. & Dubnau, D. DNA uptake during bacterial transformation. Nat. Rev. Microbiol. 2, 241-249 (2004).
    • (2004) Nat. Rev. Microbiol , vol.2 , pp. 241-249
    • Chen, I.1    Dubnau, D.2
  • 43
    • 27744558504 scopus 로고    scopus 로고
    • Unsaturated fatty acids are inhibitors of bacterial conjugation
    • Fernandez-Lopez, R. et al. Unsaturated fatty acids are inhibitors of bacterial conjugation. Microbiology 151, 3517-3526 (2005).
    • (2005) Microbiology , vol.151 , pp. 3517-3526
    • Fernandez-Lopez, R.1
  • 44
    • 29444456637 scopus 로고    scopus 로고
    • In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis
    • Hurdle, J.G., O'Neill, A.J., Mody, L., Chopra, I. & Bradley, S.F. In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis. J. Antimicrob. Chemother. 56, 1166-1168 (2005).
    • (2005) J. Antimicrob. Chemother , vol.56 , pp. 1166-1168
    • Hurdle, J.G.1    O'Neill, A.J.2    Mody, L.3    Chopra, I.4    Bradley, S.F.5
  • 45
    • 0345827436 scopus 로고    scopus 로고
    • SOS response promotes horizontal dissemination of antibiotic resistance genes
    • Beaber, J.W., Hochhut, B. & Waldor, M.K. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427, 72-74 (2004).
    • (2004) Nature , vol.427 , pp. 72-74
    • Beaber, J.W.1    Hochhut, B.2    Waldor, M.K.3
  • 46
    • 33846064688 scopus 로고    scopus 로고
    • Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci
    • Moritz, E.M. & Hergenrother, P.J. Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci. Proc. Natl. Acad. Sci. USA 104, 311-316 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 311-316
    • Moritz, E.M.1    Hergenrother, P.J.2
  • 49
    • 0038104900 scopus 로고    scopus 로고
    • Escherichia coli can contribute to the production of Shiga toxin
    • Gamage, S.D., Strasser, J.E., Chalk, C.L. & Weiss, A.A. Nonpathogenic Escherichia coli can contribute to the production of Shiga toxin. Infect. Immun. 71, 3107-3115 (2003).
    • (2003) Infect. Immun , vol.71 , pp. 3107-3115
    • Gamage, S.D.1    Strasser, J.E.2    Chalk, C.L.3
  • 50
    • 0033166233 scopus 로고    scopus 로고
    • Influence of RecA on in vivo virulence and Shiga toxin 2 production in Escherichia coli pathogens
    • Fuchs, S. et al. Influence of RecA on in vivo virulence and Shiga toxin 2 production in Escherichia coli pathogens. Microb. Pathog. 27, 13-23 (1999).
    • (1999) Microb. Pathog , vol.27 , pp. 13-23
    • Fuchs, S.1
  • 51
    • 0344393473 scopus 로고    scopus 로고
    • Transcription of the toxin genes present within the Staphylococcal phage φSa3ms is intimately linked with the phage's life cycle
    • Sumby, P. & Waldor, M.K. Transcription of the toxin genes present within the Staphylococcal phage φSa3ms is intimately linked with the phage's life cycle. J. Bacteriol. 185, 6841-6851 (2003).
    • (2003) J. Bacteriol , vol.185 , pp. 6841-6851
    • Sumby, P.1    Waldor, M.K.2
  • 52
    • 4444356917 scopus 로고    scopus 로고
    • Antibiotic-induced lateral transfer of antibiotic resistance
    • Hastings, P.J., Rosenberg, S.M. & Slack, A. Antibiotic-induced lateral transfer of antibiotic resistance. Trends Microbiol. 12, 401-404 (2004).
    • (2004) Trends Microbiol , vol.12 , pp. 401-404
    • Hastings, P.J.1    Rosenberg, S.M.2    Slack, A.3
  • 53
    • 0029057714 scopus 로고
    • Development of resistance during antimicrobial therapy: A review of antibiotic classes and patient characteristics in 173 studies
    • Fish, D.N., Piscitelli, S.C. & Danziger, L.H. Development of resistance during antimicrobial therapy: a review of antibiotic classes and patient characteristics in 173 studies. Pharmacotherapy 15, 279-291 (1995).
    • (1995) Pharmacotherapy , vol.15 , pp. 279-291
    • Fish, D.N.1    Piscitelli, S.C.2    Danziger, L.H.3
  • 54
    • 84964105753 scopus 로고
    • Observations on the mechanism of action of penicillin
    • Hobby, G.L., Meyer, K. & Chaffee, E. Observations on the mechanism of action of penicillin. Proc. Soc. Exp. Biol. Med. 50, 281-285 (1942).
    • (1942) Proc. Soc. Exp. Biol. Med , vol.50 , pp. 281-285
    • Hobby, G.L.1    Meyer, K.2    Chaffee, E.3
  • 55
    • 10044266575 scopus 로고    scopus 로고
    • Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
    • Keren, I., Shah, D., Spoering, A., Kaldalu, N. & Lewis, K. Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J. Bacteriol. 186, 8172-8180 (2004).
    • (2004) J. Bacteriol , vol.186 , pp. 8172-8180
    • Keren, I.1    Shah, D.2    Spoering, A.3    Kaldalu, N.4    Lewis, K.5
  • 56
    • 16244399491 scopus 로고    scopus 로고
    • Phenotypic tolerance: Antibiotic enrichment of noninherited resistance in bacterial populations
    • Wiuff, C. et al. Phenotypic tolerance: antibiotic enrichment of noninherited resistance in bacterial populations. Antimicrob. Agents Chemother. 49, 1483-1494 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 1483-1494
    • Wiuff, C.1
  • 57
    • 33745189789 scopus 로고    scopus 로고
    • Non-inherited antibiotic resistance
    • Levin, B.R. & Rozen, D.E. Non-inherited antibiotic resistance. Nat. Rev. Microbiol. 4, 556-562 (2006).
    • (2006) Nat. Rev. Microbiol , vol.4 , pp. 556-562
    • Levin, B.R.1    Rozen, D.E.2
  • 58
    • 0037541096 scopus 로고    scopus 로고
    • Susceptibility testing of Pseudomonas aeruginosa isolates and clinical response to parenteral antibiotic administration: Lack of association in cystic fibrosis
    • Smith, A.L., Fiel, S.B., Mayer-Hamblett, N., Ramsey, B. & Burns, J.L. Susceptibility testing of Pseudomonas aeruginosa isolates and clinical response to parenteral antibiotic administration: lack of association in cystic fibrosis. Chest 123, 1495-1502 (2003).
    • (2003) Chest , vol.123 , pp. 1495-1502
    • Smith, A.L.1    Fiel, S.B.2    Mayer-Hamblett, N.3    Ramsey, B.4    Burns, J.L.5
  • 59
    • 0023567165 scopus 로고
    • Emergence of resistance in gram-negative bacteria during therapy with expanded-spectrum cephalosporins
    • Dworzack, D.L., Pugsley, M.P., Sanders, C.C. & Horowitz, E.A. Emergence of resistance in gram-negative bacteria during therapy with expanded-spectrum cephalosporins. Eur. J. Clin. Microbiol. 6, 456-459 (1987).
    • (1987) Eur. J. Clin. Microbiol , vol.6 , pp. 456-459
    • Dworzack, D.L.1    Pugsley, M.P.2    Sanders, C.C.3    Horowitz, E.A.4
  • 61
    • 33845607284 scopus 로고    scopus 로고
    • Persister cells, dormancy and infectious disease
    • Lewis, K. Persister cells, dormancy and infectious disease. Nat. Rev. Microbiol. 5, 48-56 (2007).
    • (2007) Nat. Rev. Microbiol , vol.5 , pp. 48-56
    • Lewis, K.1
  • 62
    • 0024991947 scopus 로고
    • Influence of growth rate on susceptibility to antimicrobial agents: Biofilms, cell cycle, dormancy, and stringent response
    • Gilbert, P., Collier, P.J. & Brown, M.R. Influence of growth rate on susceptibility to antimicrobial agents: biofilms, cell cycle, dormancy, and stringent response. Antimicrob. Agents Chemother. 34, 1865-1868 (1990).
    • (1990) Antimicrob. Agents Chemother , vol.34 , pp. 1865-1868
    • Gilbert, P.1    Collier, P.J.2    Brown, M.R.3
  • 63
    • 0015709565 scopus 로고
    • The killing of bacteria by cell wall inhibitors
    • Rogers, H.J. The killing of bacteria by cell wall inhibitors. Contrib. Microbiol. Immunol. 1, 117-134 (1973).
    • (1973) Contrib. Microbiol. Immunol , vol.1 , pp. 117-134
    • Rogers, H.J.1
  • 64
    • 33646549559 scopus 로고    scopus 로고
    • Increased persistence in Escherichia coli caused by controlled expression of toxins or other unrelated proteins
    • Vazquez-Laslop, N., Lee, H. & Neyfakh, A.A. Increased persistence in Escherichia coli caused by controlled expression of toxins or other unrelated proteins. J. Bacteriol. 188, 3494-3497 (2006).
    • (2006) J. Bacteriol , vol.188 , pp. 3494-3497
    • Vazquez-Laslop, N.1    Lee, H.2    Neyfakh, A.A.3
  • 65
    • 33747436591 scopus 로고    scopus 로고
    • Persisters: A distinct physiological state of E. coli
    • Shah, D. et al. Persisters: a distinct physiological state of E. coli. BMC Microbiol. 6, 53 (2006).
    • (2006) BMC Microbiol , vol.6 , pp. 53
    • Shah, D.1
  • 67
    • 0020590028 scopus 로고
    • hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
    • Moyed, H.S. & Bertrand, K.P. hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J. Bacteriol. 155, 768-775 (1983).
    • (1983) J. Bacteriol , vol.155 , pp. 768-775
    • Moyed, H.S.1    Bertrand, K.P.2
  • 68
    • 0033053785 scopus 로고    scopus 로고
    • Stabilization of Rhizobium symbiosis plasmids
    • Falla, T.J. & Chopra, I. Stabilization of Rhizobium symbiosis plasmids. Microbiology 145, 515-516 (1999).
    • (1999) Microbiology , vol.145 , pp. 515-516
    • Falla, T.J.1    Chopra, I.2
  • 69
    • 27944437497 scopus 로고    scopus 로고
    • Toxin-antitoxin modules as bacterial metabolic stress managers
    • Buts, L., Lah, J., Dao-Thi, M.H., Wyns, L. & Loris, R. Toxin-antitoxin modules as bacterial metabolic stress managers. Trends Biochem. Sci. 30, 672-679 (2005).
    • (2005) Trends Biochem. Sci , vol.30 , pp. 672-679
    • Buts, L.1    Lah, J.2    Dao-Thi, M.H.3    Wyns, L.4    Loris, R.5
  • 70
    • 0037428226 scopus 로고    scopus 로고
    • The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site
    • Pedersen, K. et al. The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell 112, 131-140 (2003).
    • (2003) Cell , vol.112 , pp. 131-140
    • Pedersen, K.1
  • 71
    • 0041825422 scopus 로고    scopus 로고
    • Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA
    • Christensen, S.K., Pedersen, K., Hansen, F.G. & Gerdes, K. Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J. Mol. Biol. 332, 809-819 (2003).
    • (2003) J. Mol. Biol , vol.332 , pp. 809-819
    • Christensen, S.K.1    Pedersen, K.2    Hansen, F.G.3    Gerdes, K.4
  • 72
    • 14244266086 scopus 로고    scopus 로고
    • Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes
    • Pandey, D.P. & Gerdes, K. Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res. 33, 966-976 (2005).
    • (2005) Nucleic Acids Res , vol.33 , pp. 966-976
    • Pandey, D.P.1    Gerdes, K.2
  • 73
    • 0036067108 scopus 로고    scopus 로고
    • Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins
    • Pedersen, K., Christensen, S.K. & Gerdes, K. Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol. Microbiol. 45, 501-510 (2002).
    • (2002) Mol. Microbiol , vol.45 , pp. 501-510
    • Pedersen, K.1    Christensen, S.K.2    Gerdes, K.3
  • 74
    • 0028270774 scopus 로고
    • Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis
    • Black, D.S., Irwin, B. & Moyed, H.S. Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis. J. Bacteriol. 176, 4081-4091 (1994).
    • (1994) J. Bacteriol , vol.176 , pp. 4081-4091
    • Black, D.S.1    Irwin, B.2    Moyed, H.S.3
  • 75
    • 0344826574 scopus 로고    scopus 로고
    • Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis
    • Korch, S.B., Henderson, T.A. & Hill, T.M. Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis. Mol. Microbiol. 50, 1199-1213 (2003).
    • (2003) Mol. Microbiol , vol.50 , pp. 1199-1213
    • Korch, S.B.1    Henderson, T.A.2    Hill, T.M.3
  • 76
    • 34250218203 scopus 로고    scopus 로고
    • PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli
    • Li, Y. & Zhang, Y. PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. Antimicrob. Agents Chemother. 51, 2092-2099 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 2092-2099
    • Li, Y.1    Zhang, Y.2
  • 77
    • 34548496904 scopus 로고    scopus 로고
    • Tsilibaris, V., Maenhaut-Michel, G., Mine, N. & Van Melderen, L. What is the benefit for E. coli to have multiple toxin-antitoxin systems in their genomes? J. Bacteriol., published online 18 May 2007 (doi:10.1128/JB.00527-07).
    • Tsilibaris, V., Maenhaut-Michel, G., Mine, N. & Van Melderen, L. What is the benefit for E. coli to have multiple toxin-antitoxin systems in their genomes? J. Bacteriol., published online 18 May 2007 (doi:10.1128/JB.00527-07).
  • 78
    • 33744729683 scopus 로고    scopus 로고
    • Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: Effects on macromolecular synthesis and persister formation
    • Korch, S.B. & Hill, T.M. Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: effects on macromolecular synthesis and persister formation. J. Bacteriol. 188, 3826-3836 (2006).
    • (2006) J. Bacteriol , vol.188 , pp. 3826-3836
    • Korch, S.B.1    Hill, T.M.2
  • 79
    • 33845428404 scopus 로고    scopus 로고
    • Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli
    • Correia, F.F. et al. Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli. J. Bacteriol. 188, 8360-8367 (2006).
    • (2006) J. Bacteriol , vol.188 , pp. 8360-8367
    • Correia, F.F.1
  • 80
    • 33745904995 scopus 로고    scopus 로고
    • GlpD and PlsB participate in persister cell formation in Escherichia coli
    • Spoering, A.L., Vulic, M. & Lewis, K. GlpD and PlsB participate in persister cell formation in Escherichia coli. J. Bacteriol. 188, 5136-5144 (2006).
    • (2006) J. Bacteriol , vol.188 , pp. 5136-5144
    • Spoering, A.L.1    Vulic, M.2    Lewis, K.3
  • 81
    • 0036851258 scopus 로고    scopus 로고
    • Chronic bacterial infections: Living with unwanted guests
    • Young, D., Hussell, T. & Dougan, G. Chronic bacterial infections: living with unwanted guests. Nat. Immunol. 3, 1026-1032 (2002).
    • (2002) Nat. Immunol , vol.3 , pp. 1026-1032
    • Young, D.1    Hussell, T.2    Dougan, G.3
  • 82
    • 0036834373 scopus 로고    scopus 로고
    • The future challenges facing the development of new antimicrobial drugs
    • Coates, A., Hu, Y., Bax, R. & Page, C. The future challenges facing the development of new antimicrobial drugs. Nat. Rev. Drug Discov. 1, 895-910 (2002).
    • (2002) Nat. Rev. Drug Discov , vol.1 , pp. 895-910
    • Coates, A.1    Hu, Y.2    Bax, R.3    Page, C.4
  • 83
    • 0038784717 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence
    • Smith, I. Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clin. Microbiol. Rev. 16, 463-496 (2003).
    • (2003) Clin. Microbiol. Rev , vol.16 , pp. 463-496
    • Smith, I.1
  • 84
    • 0036139212 scopus 로고    scopus 로고
    • Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific
    • Fritz, C., Maass, S., Kreft, A. & Bange, F.C. Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific. Infect. Immun. 70, 286-291 (2002).
    • (2002) Infect. Immun , vol.70 , pp. 286-291
    • Fritz, C.1    Maass, S.2    Kreft, A.3    Bange, F.C.4
  • 85
    • 0342794213 scopus 로고    scopus 로고
    • Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
    • McKinney, J.D. et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature 406, 735-738 (2000).
    • (2000) Nature , vol.406 , pp. 735-738
    • McKinney, J.D.1
  • 86
    • 16244421659 scopus 로고    scopus 로고
    • Isocitrate lyase (AceA) is required for Salmonella persistence but not for acute lethal infection in mice
    • Fang, F.C., Libby, S.J., Castor, M.E. & Fung, A.M. Isocitrate lyase (AceA) is required for Salmonella persistence but not for acute lethal infection in mice. Infect. Immun. 73, 2547-2549 (2005).
    • (2005) Infect. Immun , vol.73 , pp. 2547-2549
    • Fang, F.C.1    Libby, S.J.2    Castor, M.E.3    Fung, A.M.4
  • 87
    • 34250328344 scopus 로고    scopus 로고
    • Membrane-bound nitrate reductase is required for anaerobic growth in cystic fibrosis sputum
    • Palmer, K.L., Brown, S.A. & Whiteley, M. Membrane-bound nitrate reductase is required for anaerobic growth in cystic fibrosis sputum. J. Bacteriol. 189, 4449-4455 (2007).
    • (2007) J. Bacteriol , vol.189 , pp. 4449-4455
    • Palmer, K.L.1    Brown, S.A.2    Whiteley, M.3
  • 88
    • 34247143197 scopus 로고    scopus 로고
    • Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis
    • Cho, S.H. et al. Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 51, 1380-1385 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 1380-1385
    • Cho, S.H.1
  • 89
    • 33744814106 scopus 로고    scopus 로고
    • Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
    • Smith, E.E. et al. Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc. Natl. Acad. Sci. USA 103, 8487-8492 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8487-8492
    • Smith, E.E.1
  • 90
    • 34547226145 scopus 로고    scopus 로고
    • Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing
    • Mwangi, M.M. et al. Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proc. Natl. Acad. Sci. USA 104, 9451-9456 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 9451-9456
    • Mwangi, M.M.1
  • 91
    • 14544281666 scopus 로고    scopus 로고
    • SOS-independent induction of dinB transcription by beta-lactam-mediated inhibition of cell wall synthesis in Escherichia coli
    • Perez-Capilla, T. et al. SOS-independent induction of dinB transcription by beta-lactam-mediated inhibition of cell wall synthesis in Escherichia coli. J. Bacteriol. 187, 1515-1518 (2005).
    • (2005) J. Bacteriol , vol.187 , pp. 1515-1518
    • Perez-Capilla, T.1
  • 92
    • 0035877065 scopus 로고    scopus 로고
    • Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections
    • Roy-Burman, A. et al. Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections. J. Infect. Dis. 183, 1767-1774 (2001).
    • (2001) J. Infect. Dis , vol.183 , pp. 1767-1774
    • Roy-Burman, A.1
  • 93
    • 8644222052 scopus 로고    scopus 로고
    • Type III secretion phenotypes of Pseudomonas aeruginosa strains change during infection of individuals with cystic fibrosis
    • Jain, M. et al. Type III secretion phenotypes of Pseudomonas aeruginosa strains change during infection of individuals with cystic fibrosis. J. Clin. Microbiol. 42, 5229-5237 (2004).
    • (2004) J. Clin. Microbiol , vol.42 , pp. 5229-5237
    • Jain, M.1
  • 94
    • 25444490107 scopus 로고    scopus 로고
    • Bordetella type III secretion modulates dendritic cell migration resulting in immunosuppression and bacterial persistence
    • Skinner, J.A., Pilione, M.R., Shen, H., Harvill, E.T. & Yuk, M.H. Bordetella type III secretion modulates dendritic cell migration resulting in immunosuppression and bacterial persistence. J. Immunol. 175, 4647-4652 (2005).
    • (2005) J. Immunol , vol.175 , pp. 4647-4652
    • Skinner, J.A.1    Pilione, M.R.2    Shen, H.3    Harvill, E.T.4    Yuk, M.H.5
  • 95
    • 26844521751 scopus 로고    scopus 로고
    • Type III secretion: More systems than you think
    • Troisfontaines, P. & Cornelis, G.R. Type III secretion: more systems than you think. Physiology (Bethesda) 20, 326-339 (2005).
    • (2005) Physiology (Bethesda) , vol.20 , pp. 326-339
    • Troisfontaines, P.1    Cornelis, G.R.2
  • 96
    • 33845894155 scopus 로고    scopus 로고
    • Multi-targeting by monotherapeutic antibacterials
    • Silver, L.L. Multi-targeting by monotherapeutic antibacterials. Nat. Rev. Drug Discov. 6, 41-55 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 41-55
    • Silver, L.L.1
  • 97
    • 0038779250 scopus 로고    scopus 로고
    • Variable sensitivity to bacterial methionyl-tRNA synthetase inhibitors reveals subpopulations of Streptococcus pneumoniae with two distinct methionyl-tRNA synthetase genes
    • Gentry, D.R. et al. Variable sensitivity to bacterial methionyl-tRNA synthetase inhibitors reveals subpopulations of Streptococcus pneumoniae with two distinct methionyl-tRNA synthetase genes. Antimicrob. Agents Chemother. 47, 1784-1789 (2003).
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 1784-1789
    • Gentry, D.R.1
  • 98
    • 0034644010 scopus 로고    scopus 로고
    • A triclosan-resistant bacterial enzyme
    • Heath, R.J. & Rock, C.O. A triclosan-resistant bacterial enzyme. Nature 406, 145-146 (2000).
    • (2000) Nature , vol.406 , pp. 145-146
    • Heath, R.J.1    Rock, C.O.2
  • 99
    • 17744395110 scopus 로고    scopus 로고
    • Functional divergence and horizontal transfer of type IV secretion systems
    • Frank, A.C., Alsmark, C.M., Thollesson, M. & Andersson, S.G. Functional divergence and horizontal transfer of type IV secretion systems. Mol. Biol. Evol. 22, 1325-1336 (2005).
    • (2005) Mol. Biol. Evol , vol.22 , pp. 1325-1336
    • Frank, A.C.1    Alsmark, C.M.2    Thollesson, M.3    Andersson, S.G.4


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