Resveratrol analogue 3,4,4′-trihydroxy-trans-stilbene induces apoptosis and autophagy in human non-small-cell lung cancer cells in vitro

Acta Pharmacologica Sinica

Volumn 36, Issue 10, 2015, Pages 1256-1265

  Zhang, Lu ^a   Dai, Fang ^b   Sheng, Pan Long ^a   Chen, Zhi Qiang ^a   Xu, Qi Ping ^a   Guo, Yu Qi ^c  

^a HENAN UNIVERSITY OF TECHNOLOGY   (China)

^b LANZHOU UNIVERSITY   (China)

^c ZHENGZHOU UNIVERSITY   (China)

Author keywords

3,4,4 trihydroxy trans stilbene; 3 MA; apoptosis; autophagy; mTOR; NAC; non small cell lung cancer; resveratrol; Wortmannin

Indexed keywords

3 METHYLADENINE; 3,4,4' TRIHYDROXY TRANS STILBENE; ACETYLCYSTEINE; ACRIDINE ORANGE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BAFILOMYCIN A1; CASPASE 3; CASPASE 9; GREEN FLUORESCENT PROTEIN; LACTATE DEHYDROGENASE; MAMMALIAN TARGET OF RAPAMYCIN; NEUTRAL RED; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RESVERATROL; SURVIVIN; UNCLASSIFIED DRUG; WORTMANNIN; 3,4,4'-TRIHYDROXYSTILBENE; MTOR PROTEIN, HUMAN; STILBENE DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; LACTATE DEHYDROGENASE ASSAY; MTT ASSAY; NON SMALL CELL LUNG CANCER; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STAINING; TUNEL ASSAY; UPREGULATION; WESTERN BLOTTING; CARCINOMA, NON-SMALL-CELL LUNG; DRUG EFFECTS; LUNG; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; HUMANS; LUNG; LUNG NEOPLASMS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STILBENES; TOR SERINE-THREONINE KINASES;

EID: 84943269258     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2015.46     Document Type: Article

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