메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COAT PROTEIN; COPOLYMER; CYTOCHROME C; EPIDERMAL GROWTH FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NANOPARTICLE; RAB PROTEIN; FLUORESCENT DYE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 84943260315     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9524     Document Type: Article
Times cited : (69)

References (56)
  • 3
    • 84876812269 scopus 로고    scopus 로고
    • Signals from the lysosome: A control centre for cellular clearance and energy metabolism
    • Settembre, C., Fraldi, A., Medina, D. L., Ballabio, A. Signals from the lysosome: a control centre for cellular clearance and energy metabolism. Nat. Rev. Mol. Cell Biol. 14, 283-296 (2013).
    • (2013) Nat. Rev. Mol. Cell Biol , vol.14 , pp. 283-296
    • Settembre, C.1    Fraldi, A.2    Medina, D.L.3    Ballabio, A.4
  • 4
    • 74049133619 scopus 로고    scopus 로고
    • Subcellular targeting strategies for drug design and delivery
    • Rajendran, L., Knölker, H.-J., Simons, K. Subcellular targeting strategies for drug design and delivery. Nat. Rev. Drug Discov. 9, 29-42 (2010).
    • (2010) Nat. Rev. Drug Discov , vol.9 , pp. 29-42
    • Rajendran, L.1    Knölker, H.-J.2    Simons, K.3
  • 6
    • 40449122225 scopus 로고    scopus 로고
    • Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications
    • Tasciotti, E. et al. Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications. Nat. Nanotechnol 3, 151-157 (2008).
    • (2008) Nat. Nanotechnol , vol.3 , pp. 151-157
    • Tasciotti, E.1
  • 7
    • 67649491055 scopus 로고    scopus 로고
    • Understanding biophysicochemical interactions at the nano-bio interface
    • Nel, A. E. et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 8, 543-557 (2009).
    • (2009) Nat. Mater , vol.8 , pp. 543-557
    • Nel, A.E.1
  • 8
    • 84905718745 scopus 로고    scopus 로고
    • In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight
    • Dahlman, J. E. et al. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nat. Nanotechnol 9, 648-655 (2014).
    • (2014) Nat. Nanotechnol , vol.9 , pp. 648-655
    • Dahlman, J.E.1
  • 10
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
    • Boussif, O. et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl Acad. Sci. USA 92, 7297-7301 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 7297-7301
    • Boussif, O.1
  • 11
    • 0020635123 scopus 로고
    • Perturbation of vesicular traffic with the carboxylic ionophore monensin
    • Tartakoff, A. M. Perturbation of vesicular traffic with the carboxylic ionophore monensin. Cell 32, 1026-1028 (1983).
    • (1983) Cell , vol.32 , pp. 1026-1028
    • Tartakoff, A.M.1
  • 12
    • 79955918786 scopus 로고    scopus 로고
    • Tunable, ultrasensitive pH-responsive nanoparticles targeting specific endocytic organelles in living cells
    • Zhou, K. et al. Tunable, ultrasensitive pH-responsive nanoparticles targeting specific endocytic organelles in living cells. Angew. Chem. Int. Ed. 50, 6109-6114 (2011).
    • (2011) Angew. Chem. Int. Ed , vol.50 , pp. 6109-6114
    • Zhou, K.1
  • 13
    • 84860852602 scopus 로고    scopus 로고
    • Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli
    • Zhou, K. et al. Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli. J. Am. Chem. Soc. 134, 7803-7811 (2012).
    • (2012) J. Am. Chem. Soc , vol.134 , pp. 7803-7811
    • Zhou, K.1
  • 14
    • 84905674424 scopus 로고    scopus 로고
    • Ultra-pH sensitive nanoprobe library with broad pH tunability and fluorescence emissions
    • Ma, X. et al. Ultra-pH sensitive nanoprobe library with broad pH tunability and fluorescence emissions. J. Am. Chem. Soc. 136, 11085-11092 (2014).
    • (2014) J. Am. Chem. Soc , vol.136 , pp. 11085-11092
    • Ma, X.1
  • 15
    • 0028132679 scopus 로고
    • Ionization of poly (ethylenimine) and poly (allylamine) at various pH's
    • Suh, J., Paik, H.-J., Hwang, B. K. Ionization of poly (ethylenimine) and poly (allylamine) at various pH's. Bioorg. Chem. 22, 318-327 (1994).
    • (1994) Bioorg. Chem , vol.22 , pp. 318-327
    • Suh, J.1    Paik, H.-J.2    Hwang, B.K.3
  • 16
    • 42949156865 scopus 로고    scopus 로고
    • Selective suicide of cross-presenting CD8\+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset
    • Lin, M. L. et al. Selective suicide of cross-presenting CD8\+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset. Proc. Natl Acad. Sci. USA 105, 3029-3034 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 3029-3034
    • Lin, M.L.1
  • 17
    • 0027160539 scopus 로고
    • A rapid and sensitive hemolysis neutralization assay for palytoxin
    • Bignami, G. S. A rapid and sensitive hemolysis neutralization assay for palytoxin. Toxicon 31, 817-820 (1993).
    • (1993) Toxicon , vol.31 , pp. 817-820
    • Bignami, G.S.1
  • 18
    • 0038731763 scopus 로고    scopus 로고
    • Acidification and protein traffic
    • Weisz, O. A. Acidification and Protein Traffic. Int. Rev. Cytol. 226, 259-319 (2003).
    • (2003) Int. Rev. Cytol , vol.226 , pp. 259-319
    • Weisz, O.A.1
  • 19
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner, S. D., Schmid, S. L. Regulated portals of entry into the cell. Nature 422, 37-44 (2003).
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 20
    • 84892980829 scopus 로고    scopus 로고
    • A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals
    • Wang, Y. et al. A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals. Nat. Mater. 13, 204-212 (2014).
    • (2014) Nat. Mater , vol.13 , pp. 204-212
    • Wang, Y.1
  • 23
    • 4944246136 scopus 로고    scopus 로고
    • The evolution of A-F-and V-type ATP synthases and ATPases: Reversals in function and changes in the H\+/ATP coupling ratio
    • Cross, R. L., Muller, V. The evolution of A-, F-, and V-type ATP synthases and ATPases: reversals in function and changes in the H\+/ATP coupling ratio. FEBS Lett. 576, 1-4 (2004).
    • (2004) FEBS Lett , vol.576 , pp. 1-4
    • Cross, R.L.1    Muller, V.2
  • 24
    • 0037418211 scopus 로고    scopus 로고
    • Evidence for rotation of V1-ATPase
    • Imamura, H. et al. Evidence for rotation of V1-ATPase. Proc. Natl Acad. Sci. USA 100, 2312-2315 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 2312-2315
    • Imamura, H.1
  • 25
    • 0025980350 scopus 로고
    • Distribution and structure of the vacuolar H\+ ATPase in endosomes and lysosomes from LLC-PK1 cells
    • Rodman, J. S., Stahl, P. D., Gluck, S. Distribution and structure of the vacuolar H\+ ATPase in endosomes and lysosomes from LLC-PK1 cells. Exp. Cell Res. 192, 445-452 (1991).
    • (1991) Exp. Cell Res , vol.192 , pp. 445-452
    • Rodman, J.S.1    Stahl, P.D.2    Gluck, S.3
  • 26
    • 80052233389 scopus 로고    scopus 로고
    • Endosome maturation
    • Huotari, J., Helenius, A. Endosome maturation. EMBO J. 30, 3481-3500 (2011).
    • (2011) EMBO J , vol.30 , pp. 3481-3500
    • Huotari, J.1    Helenius, A.2
  • 28
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Sancak, Y. et al. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 141, 290-303 (2010).
    • (2010) Cell , vol.141 , pp. 290-303
    • Sancak, Y.1
  • 29
    • 80555143078 scopus 로고    scopus 로고
    • MTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(\+)-ATPase
    • Zoncu, R. et al. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(\+)-ATPase. Science 334, 678-683 (2011).
    • (2011) Science , vol.334 , pp. 678-683
    • Zoncu, R.1
  • 30
    • 80052841665 scopus 로고    scopus 로고
    • Regulation of TFEB and V-ATPases by mTORC1
    • Pena-Llopis, S. et al. Regulation of TFEB and V-ATPases by mTORC1. EMBO J. 30, 3242-3258 (2011).
    • (2011) EMBO J , vol.30 , pp. 3242-3258
    • Pena-Llopis, S.1
  • 31
    • 84857997408 scopus 로고    scopus 로고
    • A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
    • Settembre, C. et al. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J. 31, 1095-1108 (2012).
    • (2012) EMBO J , vol.31 , pp. 1095-1108
    • Settembre, C.1
  • 32
    • 84862539692 scopus 로고    scopus 로고
    • The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
    • Roczniak-Ferguson, A. et al. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci. Signal. 5, ra42 (2012).
    • (2012) Sci. Signal , vol.5 , pp. 42
    • Roczniak-Ferguson, A.1
  • 33
    • 84886787846 scopus 로고    scopus 로고
    • Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer
    • Kim, H. S. et al. Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell 155, 552-566 (2013).
    • (2013) Cell , vol.155 , pp. 552-566
    • Kim, H.S.1
  • 34
    • 84907519033 scopus 로고    scopus 로고
    • The lysosomal V-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism
    • Zhang, C.-S. et al. The lysosomal V-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism. Cell Metab. 20, 526-540 (2014).
    • (2014) Cell Metab , vol.20 , pp. 526-540
    • Zhang, C.-S.1
  • 35
    • 10844284696 scopus 로고    scopus 로고
    • Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
    • Ramirez, R. D. et al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 64, 9027-9034 (2004).
    • (2004) Cancer Res , vol.64 , pp. 9027-9034
    • Ramirez, R.D.1
  • 36
    • 58149357048 scopus 로고    scopus 로고
    • Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes
    • Urano, Y. et al. Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat. Med 15, 104-109 (2009).
    • (2009) Nat. Med , vol.15 , pp. 104-109
    • Urano, Y.1
  • 37
    • 84901036369 scopus 로고    scopus 로고
    • Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer
    • Viola-Villegas, N. T. et al. Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer. Proc. Natl Acad. Sci. USA 111, 7254-7259 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 7254-7259
    • Viola-Villegas, N.T.1
  • 38
    • 84876020428 scopus 로고    scopus 로고
    • Family of pH (low) insertion peptides for tumor targeting
    • Weerakkody, D. et al. Family of pH (low) insertion peptides for tumor targeting. Proc. Natl Acad. Sci. USA 110, 5834-5839 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 5834-5839
    • Weerakkody, D.1
  • 39
    • 30744478946 scopus 로고    scopus 로고
    • Micelles for the self-assembly of 'Off-On-Off' fluorescent sensors for pH windows
    • Diaz-Fernandez, Y. et al. Micelles for the self-assembly of 'Off-On-Off' fluorescent sensors for pH windows. Chemistry 12, 921-930 (2006).
    • (2006) Chemistry , vol.12 , pp. 921-930
    • Diaz-Fernandez, Y.1
  • 40
    • 48849105889 scopus 로고    scopus 로고
    • Multiplexing sensory molecules map protons near micellar membranes
    • Uchiyama, S., Iwai, K., de Silva, A. P. Multiplexing sensory molecules map protons near micellar membranes. Angew. Chem. Int. Ed. 47, 4667-4669 (2008).
    • (2008) Angew. Chem. Int. Ed , vol.47 , pp. 4667-4669
    • Uchiyama, S.1    Iwai, K.2    De Silva, A.P.3
  • 41
    • 1842781842 scopus 로고    scopus 로고
    • Stimuli-responsive polypeptide vesicles by conformation-specific assembly
    • Bellomo, E. G., Wyrsta, M. D., Pakstis, L., Pochan, D. J., Deming, T. J. Stimuli-responsive polypeptide vesicles by conformation-specific assembly. Nat. Mater. 3, 244-248 (2004).
    • (2004) Nat. Mater , vol.3 , pp. 244-248
    • Bellomo, E.G.1    Wyrsta, M.D.2    Pakstis, L.3    Pochan, D.J.4    Deming, T.J.5
  • 42
    • 47349097049 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance
    • Lee, E. S. et al. Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance. J. Control. Release 129, 228-236 (2008).
    • (2008) J. Control. Release , vol.129 , pp. 228-236
    • Lee, E.S.1
  • 43
    • 14644433029 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle
    • Lee, E. S., Na, K., Bae, Y. H. Super pH-sensitive multifunctional polymeric micelle. Nano Lett. 5, 325-329 (2005).
    • (2005) Nano Lett , vol.5 , pp. 325-329
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 44
    • 15244345124 scopus 로고    scopus 로고
    • PH-responsive copolymer assemblies for controlled release of doxorubicin
    • Gillies, E. R., Frechet, J. M. J. pH-responsive copolymer assemblies for controlled release of doxorubicin. Bioconjug. Chem. 16, 361-368 (2005).
    • (2005) Bioconjug. Chem , vol.16 , pp. 361-368
    • Gillies, E.R.1    Frechet, J.M.J.2
  • 45
    • 4644264045 scopus 로고    scopus 로고
    • Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers
    • Gillies, E. R., Jonsson, T. B., Frechet, J. M. Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers. J. Am. Chem. Soc. 126, 11936-11943 (2004).
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 11936-11943
    • Gillies, E.R.1    Jonsson, T.B.2    Frechet, J.M.3
  • 46
    • 0035847011 scopus 로고    scopus 로고
    • Cathepsin B activity regulation heparin-like glycosaminoglycans protect human cathepsin B from alkaline ph-induced inactivation
    • Almeida, P. C. et al. Cathepsin B activity regulation heparin-like glycosaminoglycans protect human cathepsin B from alkaline ph-induced inactivation. J. Biol. Chem. 276, 944-951 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 944-951
    • Almeida, P.C.1
  • 47
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia, M. A., McNeil, S. E. Immunological properties of engineered nanomaterials. Nat. Nanotechnol 2, 469-478 (2007).
    • (2007) Nat. Nanotechnol , vol.2 , pp. 469-478
    • Dobrovolskaia, M.A.1    McNeil, S.E.2
  • 48
    • 36849067019 scopus 로고    scopus 로고
    • Nanocarriers as an emerging platform for cancer therapy
    • Peer, D. et al. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol 2, 751-760 (2007).
    • (2007) Nat. Nanotechnol , vol.2 , pp. 751-760
    • Peer, D.1
  • 49
    • 84905385325 scopus 로고    scopus 로고
    • Chaotropic-anion-induced supramolecular self-assembly of ionic polymeric micelles
    • Li, Y. et al. Chaotropic-anion-induced supramolecular self-assembly of ionic polymeric micelles. Angew. Chem. 53, 8074-8078 (2014).
    • (2014) Angew. Chem , vol.53 , pp. 8074-8078
    • Li, Y.1
  • 50
    • 0033169080 scopus 로고    scopus 로고
    • A novel acidotropic pH indicator and its potential application in labeling acidic organelles of live cells
    • Diwu, Z., Chen, C.-S., Zhang, C., Klaubert, D. H., Haugland, R. P. A novel acidotropic pH indicator and its potential application in labeling acidic organelles of live cells. Chem. Biol. 6, 411-418 (1999).
    • (1999) Chem. Biol , vol.6 , pp. 411-418
    • Diwu, Z.1    Chen, C.-S.2    Zhang, C.3    Klaubert, D.H.4    Haugland, R.P.5
  • 51
    • 0018764575 scopus 로고
    • Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ
    • Thomas, J. A., Buchsbaum, R. N., Zimniak, A., Racker, E. Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18, 2210-2218 (1979).
    • (1979) Biochemistry , vol.18 , pp. 2210-2218
    • Thomas, J.A.1    Buchsbaum, R.N.2    Zimniak, A.3    Racker, E.4
  • 52
    • 0026650127 scopus 로고
    • Quick and accurate method to convert BCECF fluorescence to pHi: Calibration in three different types of cell preparations
    • James-Kracke, M. R. Quick and accurate method to convert BCECF fluorescence to pHi: calibration in three different types of cell preparations. J. Cell. Physiol. 151, 596-603 (1992).
    • (1992) J. Cell. Physiol , vol.151 , pp. 596-603
    • James-Kracke, M.R.1
  • 53
    • 0028100685 scopus 로고
    • Functional characterization of three isoforms of the Na\+/H\+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation
    • Kapus, A., Grinstein, S., Wasan, S., Kandasamy, R., Orlowski, J. Functional characterization of three isoforms of the Na\+/H\+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation. J. Biol. Chem. 269, 23544-23552 (1994).
    • (1994) J. Biol. Chem , vol.269 , pp. 23544-23552
    • Kapus, A.1    Grinstein, S.2    Wasan, S.3    Kandasamy, R.4    Orlowski, J.5
  • 54
    • 0027418205 scopus 로고
    • Measurement of co-localization of objects in dual-colour confocal images
    • Manders, E., Verbeek, F., Aten, J. Measurement of co-localization of objects in dual-colour confocal images. J. Microsc. 169, 375-382 (1993).
    • (1993) J. Microsc , vol.169 , pp. 375-382
    • Manders, E.1    Verbeek, F.2    Aten, J.3
  • 55
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • Bolte, S., Cordelières, F. P. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224, 213-232 (2006).
    • (2006) J. Microsc , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelières, F.P.2
  • 56
    • 84878396462 scopus 로고    scopus 로고
    • Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
    • Commisso, C. et al. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature 497, 633-637 (2013).
    • (2013) Nature , vol.497 , pp. 633-637
    • Commisso, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.