Z944, a novel selective t-type calcium channel antagonist delays the progression of seizures in the amygdala kindling model

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Casillas Espinosa, Pablo Miguel ^a   Hicks, Ashleigh ^a   Jeffreys, Amy ^a   Snutch, Terrance P ^b   O'Brien, Terence J ^a   Powell, Kim L ^a   Spafford, J David ^c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF WATERLOO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; CARBAMAZEPINE; ETHOSUXIMIDE; MESSENGER RNA; UNCLASSIFIED DRUG; Z 944; ACETAMIDE DERIVATIVE; ANTICONVULSIVE AGENT; BENZAMIDE DERIVATIVE; Z944 COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CAV3.1 GENE; CAV3.2 GENE; CAV3.3 GENE; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DRUG MECHANISM; DRUG SAFETY; GENE; GENE EXPRESSION; KINDLING; NONHUMAN; RAT; SEDATION; TEMPORAL LOBE EPILEPSY; AMYGDALA; ANIMAL; DISEASE MODEL; DRUG EFFECTS; PATHOLOGY; SEIZURES;

ACETAMIDES; AMYGDALA; ANIMALS; ANTICONVULSANTS; BENZAMIDES; CALCIUM CHANNEL BLOCKERS; DISEASE MODELS, ANIMAL; KINDLING, NEUROLOGIC; RATS; SEIZURES;

EID: 84943167915     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130012     Document Type: Article

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