-
1
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. 1998 Embryonic stem cell lines derived from human blastocysts. Science 6, 1145–1147. (doi:10.1126/science.282.5391.1145)
-
(1998)
Science
, vol.6
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
2
-
-
84856396104
-
GRNOPC1: The world’s first embryonic stem cell-derived therapy. Interview with Jane Lebkowski
-
Lebkowski J. 2011 GRNOPC1: the world’s first embryonic stem cell-derived therapy. Interview with Jane Lebkowski. Regen. Med. 6, 11–13. (doi:10.2217/rme.11.77)
-
(2011)
Regen. Med
, vol.6
, pp. 11-13
-
-
Lebkowski, J.1
-
3
-
-
84862001079
-
Geron’s quixotic fate
-
Scott C, Huggett B. 2012 Geron’s quixotic fate. Nat. Biotechnol. 30, 497. (doi:10.1038/nbt.2253)
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 497
-
-
Scott, C.1
Huggett, B.2
-
4
-
-
84923014395
-
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt’s macular dystrophy: Follow-up of two open-label phase 1/2 studies
-
Schwartz SD et al. 2014 Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt’s macular dystrophy: follow-up of two open-label phase 1/2 studies. Lancet 6736, 61376–61383. (doi:10.1016/S0140-6736(14)61376-3)
-
(2014)
Lancet
, vol.6736
, pp. 61376-61383
-
-
Schwartz, S.D.1
-
5
-
-
84929295709
-
Treatment of macular degeneration using human embryonic stem cell derived retinal pigment epithelium: Preliminary results in Asian patients
-
Park K-M, Kim H-J, Lee JH, Choi J, Young Chong S, Shim SH, Del Priore LV, Lanza R. 2015 Treatment of macular degeneration using human embryonic stem cell derived retinal pigment epithelium: preliminary results in Asian patients. Stem Cell Rep. 4, 860–872. (doi:10.1016/j.stemcr.2015.04.005)
-
(2015)
Stem Cell Rep
, vol.4
, pp. 860-872
-
-
Park, K.-M.1
Kim, H.-J.2
Lee, J.H.3
Choi, J.4
Young Chong, S.5
Shim, S.H.6
Del Priore, L.V.7
Lanza, R.8
-
6
-
-
84907752479
-
Japan stem cell trial stirs envy
-
Reardon S, Cyranoski D. 2014 Japan stem cell trial stirs envy. Nature 513, 287–288. (doi:0.1038/513287a)
-
(2014)
Nature
, vol.513
, pp. 287-288
-
-
Reardon, S.1
Cyranoski, D.2
-
7
-
-
84873295436
-
Mechanisms of immune privilege in the posterior eye
-
Stein-Streilein J. 2013 Mechanisms of immune privilege in the posterior eye. Int. Rev. Immunol. 32, 42–56. (doi:10.3109/08830185.2012.740535)
-
(2013)
Int. Rev. Immunol
, vol.32
, pp. 42-56
-
-
Stein-Streilein, J.1
-
8
-
-
77953962770
-
Immune regulation in the retina
-
Detrick B, Hooks JJ. 2010 Immune regulation in the retina. Immunol. Res. 47, 153–161. (doi:10.1007/s12026-009-8146-1)
-
(2010)
Immunol. Res
, vol.47
, pp. 153-161
-
-
Detrick, B.1
Hooks, J.J.2
-
9
-
-
40849145527
-
Age-related macular degeneration: Diagnosis and management
-
Cook HL, Patel PJ, Tufail A. 2008 Age-related macular degeneration: diagnosis and management. Br. Med. Bull. 85, 127–149. (doi:10.1093/bmb/ldn012)
-
(2008)
Br. Med. Bull
, vol.85
, pp. 127-149
-
-
Cook, H.L.1
Patel, P.J.2
Tufail, A.3
-
10
-
-
35348953619
-
RPE transplantation and its role in retinal disease
-
da Cruz L, Chen FK, Ahmado A, Greenwood J, Coffey P. 2007 RPE transplantation and its role in retinal disease. Prog. Retin. Eye Res. 26, 598–635. (doi:10.1016/j.preteyeres.2007.07.001)
-
(2007)
Prog. Retin. Eye Res
, vol.26
, pp. 598-635
-
-
Da Cruz, L.1
Chen, F.K.2
Ahmado, A.3
Greenwood, J.4
Coffey, P.5
-
11
-
-
78651299482
-
The retinal pigment epithelium in health and disease
-
Sparrow JR, Hicks D, Hamel CP. 2010 The retinal pigment epithelium in health and disease. Curr. Mol. Med. 10, 802–823. (doi:10.2174/156652410793937813)
-
(2010)
Curr. Mol. Med
, vol.10
, pp. 802-823
-
-
Sparrow, J.R.1
Hicks, D.2
Hamel, C.P.3
-
12
-
-
84891155619
-
Transplantation of human bone marrow mesenchymal stem cells as a thin subretinal layer ameliorates retinal degeneration in a rat model of retinal dystrophy
-
Tzameret A et al. 2014 Transplantation of human bone marrow mesenchymal stem cells as a thin subretinal layer ameliorates retinal degeneration in a rat model of retinal dystrophy. Exp. Eye Res. 118, 135–144. (doi:10.1016/j.exer.2013.10.023)
-
(2014)
Exp. Eye Res
, vol.118
, pp. 135-144
-
-
Tzameret, A.1
-
13
-
-
65449129958
-
Longterm visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration
-
Chen FK, Uppal GS, MacLaren RE, Coffey PJ, Rubin GS, Tufail A, Aylward GW, Da Cruz L. 2009 Longterm visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration. Clin. Exp. Ophthalmol. 37, 275–285. (doi:10.1111/j.1442-9071.2009.01915.x)
-
(2009)
Clin. Exp. Ophthalmol
, vol.37
, pp. 275-285
-
-
Chen, F.K.1
Uppal, G.S.2
Maclaren, R.E.3
Coffey, P.J.4
Rubin, G.S.5
Tufail, A.6
Aylward, G.W.7
Da Cruz, L.8
-
14
-
-
64049087009
-
Comparison of macular translocation with patch graft in neovascular age-related macular degeneration
-
Chen FK, Patel PJ, Uppal GS, Rubin GS, Coffey PJ, Aylward GW, Da Cruz LA. 2009 Comparison of macular translocation with patch graft in neovascular age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 50, 1848–1855. (doi:10.1167/iovs.08-2845)
-
(2009)
Invest. Ophthalmol. Vis. Sci
, vol.50
, pp. 1848-1855
-
-
Chen, F.K.1
Patel, P.J.2
Uppal, G.S.3
Rubin, G.S.4
Coffey, P.J.5
Aylward, G.W.6
Da Cruz, L.A.7
-
15
-
-
84891607199
-
Adaptive optics imaging shows rescue of macula cone photoreceptors
-
Muthiah MN, Keane PA, Zhong J, Gias C, Uppal G, Coffey PJ, da Cruz L. 2014 Adaptive optics imaging shows rescue of macula cone photoreceptors. Ophthalmology 121, 430–431. (doi:10.1016/j.ophtha.2013.10.008)
-
(2014)
Ophthalmology
, vol.121
, pp. 430-431
-
-
Muthiah, M.N.1
Keane, P.A.2
Zhong, J.3
Gias, C.4
Uppal, G.5
Coffey, P.J.6
Da Cruz, L.7
-
16
-
-
61449175932
-
Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay
-
Carr AJ et al. 2009 Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay. Mol. Vis. 15, 283–295.
-
(2009)
Mol. Vis
, vol.15
, pp. 283-295
-
-
Carr, A.J.1
-
17
-
-
56349103166
-
Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation
-
Vugler A et al. 2008 Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation. Exp. Neurol. 214, 347–361. (doi:10.1016/j.expneurol.2008.09.007)
-
(2008)
Exp. Neurol
, vol.214
, pp. 347-361
-
-
Vugler, A.1
-
18
-
-
84855517118
-
Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives
-
Salero E, Blenkinsop TA, Corneo B, Harris A, Rabin D, Stern JH, Temple S. 2012 Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives. Cell Stem Cell 10, 88–95. (doi:10.1016/j.stem.2011.11.018)
-
(2012)
Cell Stem Cell
, vol.10
, pp. 88-95
-
-
Salero, E.1
Blenkinsop, T.A.2
Corneo, B.3
Harris, A.4
Rabin, D.5
Stern, J.H.6
Temple, S.7
-
19
-
-
84938593265
-
A FOXM1 dependent mesenchymal–epithelial transition in retinal pigment epithelium cells
-
Choudhary P, Dodsworth B, Sidders B, Gutteridge A, Michaelides C, Duckworth J, Whiting P, Benn C. 2015 A FOXM1 dependent mesenchymal–epithelial transition in retinal pigment epithelium cells. PLoS ONE 10, e0130379. (doi:10.1371/journal.pone.0130379)
-
(2015)
Plos ONE
, vol.10
-
-
Choudhary, P.1
Dodsworth, B.2
Sidders, B.3
Gutteridge, A.4
Michaelides, C.5
Duckworth, J.6
Whiting, P.7
Benn, C.8
-
20
-
-
84919785953
-
Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures
-
Hsiung J, Zhu D, Hinton DR. 2015 Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures. Stem Cells Transl. Med. 4, 10–20. (doi:10.5966/sctm.2014-0205)
-
(2015)
Stem Cells Transl. Med
, vol.4
, pp. 10-20
-
-
Hsiung, J.1
Zhu, D.2
Hinton, D.R.3
-
21
-
-
79955372799
-
Comparison of FRPE and human embryonic stem cell-derived RPE behavior on aged human Bruch’s membrane
-
Sugino IK et al. 2011 Comparison of FRPE and human embryonic stem cell-derived RPE behavior on aged human Bruch’s membrane. Invest. Ophthalmol. Vis. Sci. 52, 4979–4997. (doi:10.1167/iovs.10-5386)
-
(2011)
Invest. Ophthalmol. Vis. Sci
, vol.52
, pp. 4979-4997
-
-
Sugino, I.K.1
-
22
-
-
84880779573
-
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: Improved survival when implanted as a monolayer
-
Diniz B et al. 2013 Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. Invest. Ophthalmol. Vis. Sci. 54, 5087–5096. (doi:10.1167/iovs.12-11239)
-
(2013)
Invest. Ophthalmol. Vis. Sci
, vol.54
, pp. 5087-5096
-
-
Diniz, B.1
-
23
-
-
84894413349
-
Current knowledge and trends in age-related macular degeneration: Genetics, epidemiology, and prevention
-
Velez-Montoya R, Oliver SC, Olson JL, Fine SL, Quiroz-Mercado H, Mandava N. 2014 Current knowledge and trends in age-related macular degeneration: genetics, epidemiology, and prevention. Retina 34, 423–441. (doi:10.1097/IAE.0000000000000036)
-
(2014)
Retina
, vol.34
, pp. 423-441
-
-
Velez-Montoya, R.1
Oliver, S.C.2
Olson, J.L.3
Fine, S.L.4
Quiroz-Mercado, H.5
Mandava, N.6
-
24
-
-
84896724988
-
Emerging treatments for wet age-related macular degeneration
-
Smith AG, Kaiser PK. 2014 Emerging treatments for wet age-related macular degeneration. Expert Opin. Emerg. Drugs 19, 157–164. (doi:10.1517/14728214.2014.884559)
-
(2014)
Expert Opin. Emerg. Drugs
, vol.19
, pp. 157-164
-
-
Smith, A.G.1
Kaiser, P.K.2
-
25
-
-
84898981975
-
Population screening for variant Creutzfeldt-Jakob disease using a novel blood test: Diagnostic accuracy and feasibility study
-
Jackson GS et al. 2014 Population screening for variant Creutzfeldt-Jakob disease using a novel blood test: diagnostic accuracy and feasibility study. JAMA Neurol. 71, 421–428. (doi:10.1001/jamaneurol.2013.6001)
-
(2014)
JAMA Neurol
, vol.71
, pp. 421-428
-
-
Jackson, G.S.1
-
26
-
-
77950651133
-
High-resolution DNA analysis of human embryonic stem cell lines reveals cultureinduced copy number changes and loss of heterozygosity
-
Närvä E et al. 2010 High-resolution DNA analysis of human embryonic stem cell lines reveals cultureinduced copy number changes and loss of heterozygosity. Nat. Biotechnol. 28, 371–377. (doi:10.1038/nbt.1615)
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 371-377
-
-
Närvä, E.1
-
27
-
-
84942852568
-
Teratoma formation: A tool for monitoring pluripotency in stem cell research
-
Nelakanti RV, Kooreman NG, Wu JC. 2015 Teratoma formation: a tool for monitoring pluripotency in stem cell research. Curr. Protoc. Stem Cell Biol. 32, 4A81–4A817. (doi:10.1002/9780470151808.sc04a08s32)
-
(2015)
Curr. Protoc. Stem Cell Biol
, vol.32
, pp. 4A81-4A817
-
-
Nelakanti, R.V.1
Kooreman, N.G.2
Wu, J.C.3
-
28
-
-
84866080418
-
Lessons from human teratomas to guide development of safe stem cell therapies
-
Cunningham JJ, Ulbright TM, Pera MF, Looijenga LH. 2012 Lessons from human teratomas to guide development of safe stem cell therapies. Nat. Biotechnol. 30, 849–857. (doi:10.1038/nbt.2329)
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 849-857
-
-
Cunningham, J.J.1
Ulbright, T.M.2
Pera, M.F.3
Looijenga, L.H.4
-
29
-
-
84866678032
-
Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny
-
Gropp M et al. 2012 Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny. PLoS ONE 7, e45532. (doi:10.1371/journal.pone.0045532)
-
(2012)
Plos ONE
, vol.7
-
-
Gropp, M.1
-
30
-
-
33646574938
-
Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site
-
Cooke MJ, Stojkovic M, Przyborski SA. 2006 Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site. Stem Cells Dev. 15, 254–259. (doi:10.1089/scd.2006.15.254)
-
(2006)
Stem Cells Dev
, vol.15
, pp. 254-259
-
-
Cooke, M.J.1
Stojkovic, M.2
Przyborski, S.A.3
-
31
-
-
84870268385
-
Derivation of dopaminergic neurons from pluripotent stem cells
-
Studer L. 2012 Derivation of dopaminergic neurons from pluripotent stem cells. Prog. Brain Res. 200, 243–263. (doi:10.1016/B978-0-444-59575-1.00011-9)
-
(2012)
Prog. Brain Res
, vol.200
, pp. 243-263
-
-
Studer, L.1
-
32
-
-
84910673362
-
Generation of functional human pancreatic b cells in vitro
-
Pagliuca FW, Millman JR, Gurtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA. 2014 Generation of functional human pancreatic b cells in vitro. Cell 159, 428–439. (doi:10.1016/j.cell.2014.09.040)
-
(2014)
Cell
, vol.159
, pp. 428-439
-
-
Pagliuca, F.W.1
Millman, J.R.2
Gurtler, M.3
Segel, M.4
Van Dervort, A.5
Ryu, J.H.6
Peterson, Q.P.7
Greiner, D.8
Melton, D.A.9
-
33
-
-
84870030633
-
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
-
Shi Y, Kirwan P, Livesey FJ. 2012 Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nat. Protoc. 7, 1836–1846. (doi:10.1038/nprot.2012.116)
-
(2012)
Nat. Protoc
, vol.7
, pp. 1836-1846
-
-
Shi, Y.1
Kirwan, P.2
Livesey, F.J.3
|