메뉴 건너뛰기




Volumn 21, Issue 15, 2015, Pages 3471-3479

Cytoplasmic accumulation of sequestosome 1 (p62) is a predictor of biochemical recurrence, rapid tumor cell proliferation, and genomic instability in prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN P62; TRANSCRIPTION FACTOR ERG; PTEN PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84942925503     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-0620     Document Type: Article
Times cited : (43)

References (41)
  • 3
    • 84864011477 scopus 로고    scopus 로고
    • Prostate cancer-uncertainty and a way forward
    • Thompson IM Jr, Tangen CM. Prostate cancer-uncertainty and a way forward. N Engl J Med 2012;367:270-1.
    • (2012) N Engl J Med , vol.367 , pp. 270-271
    • Thompson, I.M.1    Tangen, C.M.2
  • 4
    • 84881566784 scopus 로고    scopus 로고
    • Role of p62/SQSTM1 in liver physiology and pathogenesis
    • Manley S, Williams JA, Ding WX. Role of p62/SQSTM1 in liver physiology and pathogenesis. Exp Biol Med 2013;238:525-38.
    • (2013) Exp Biol Med , vol.238 , pp. 525-538
    • Manley, S.1    Williams, J.A.2    Ding, W.X.3
  • 6
    • 27944504351 scopus 로고    scopus 로고
    • p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 2005; 171:603-14.
    • (2005) J Cell Biol , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6
  • 7
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008;451:1069-75.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 8
    • 84862811895 scopus 로고    scopus 로고
    • Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma
    • Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, et al. Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma. Cancer Sci 2012;103:760-6.
    • (2012) Cancer Sci , vol.103 , pp. 760-766
    • Inoue, D.1    Suzuki, T.2    Mitsuishi, Y.3    Miki, Y.4    Suzuki, S.5    Sugawara, S.6
  • 9
    • 0037994340 scopus 로고    scopus 로고
    • p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells
    • Thompson HG, Harris JW, Wold BJ, Lin F, Brody JP. p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells. Oncogene 2003;22:2322-33.
    • (2003) Oncogene , vol.22 , pp. 2322-2333
    • Thompson, H.G.1    Harris, J.W.2    Wold, B.J.3    Lin, F.4    Brody, J.P.5
  • 10
    • 84892941985 scopus 로고    scopus 로고
    • Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer
    • Luo RZ, Yuan ZY, Li M, Xi SY, Fu J, He J. Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer. Onco Targets Ther 2013;6:883-8.
    • (2013) Onco Targets Ther , vol.6 , pp. 883-888
    • Luo, R.Z.1    Yuan, Z.Y.2    Li, M.3    Xi, S.Y.4    Fu, J.5    He, J.6
  • 11
    • 84877887193 scopus 로고    scopus 로고
    • FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells
    • Ren SX, Shen J, Cheng AS, Lu L, Chan RL, Li ZJ, et al. FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. PLoS One 2013;8: e63641.
    • (2013) PLoS One , vol.8
    • Ren, S.X.1    Shen, J.2    Cheng, A.S.3    Lu, L.4    Chan, R.L.5    Li, Z.J.6
  • 13
    • 79955492012 scopus 로고    scopus 로고
    • Persistent activation of nrf2 through p62 in hepatocellular carcinoma cells
    • Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, et al. Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol 2011;193:275-84.
    • (2011) J Cell Biol , vol.193 , pp. 275-284
    • Inami, Y.1    Waguri, S.2    Sakamoto, A.3    Kouno, T.4    Nakada, K.5    Hino, O.6
  • 15
    • 84884765851 scopus 로고    scopus 로고
    • Alteration of p62/SQSTM1 expression is uncommon in gastrointestinal and prostate cancer tissues
    • Je EM, Yoo NJ, Lee SH. Alteration of p62/SQSTM1 expression is uncommon in gastrointestinal and prostate cancer tissues. Gut Liver 2013;7: 625-7.
    • (2013) Gut Liver , vol.7 , pp. 625-627
    • Je, E.M.1    Yoo, N.J.2    Lee, S.H.3
  • 16
    • 57749108319 scopus 로고    scopus 로고
    • Clinical significance of p53 alterations in surgically treated prostate cancers
    • Schlomm T, Iwers L, Kirstein P, Jessen B, Kollermann J, Minner S, et al. Clinical significance of p53 alterations in surgically treated prostate cancers. Mod Pathol 2008;21:1371-9.
    • (2008) Mod Pathol , vol.21 , pp. 1371-1379
    • Schlomm, T.1    Iwers, L.2    Kirstein, P.3    Jessen, B.4    Kollermann, J.5    Minner, S.6
  • 18
    • 84873607610 scopus 로고    scopus 로고
    • Integrative genomic analyses reveal androgen-driven somatic alteration landscape in early-onset prostate cancer
    • Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, Minner S, et al. Integrative genomic analyses reveal androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell 2013;23:159-70.
    • (2013) Cancer Cell , vol.23 , pp. 159-170
    • Weischenfeldt, J.1    Simon, R.2    Feuerbach, L.3    Schlangen, K.4    Weichenhan, D.5    Minner, S.6
  • 19
    • 80052841071 scopus 로고    scopus 로고
    • ERG status is unrelated to PSA recurrence inradically operated prostate cancer in the absence of antihormonal therapy
    • Minner S, Enodien M, Sirma H, Luebke AM, Krohn A, Mayer PS, et al. ERG status is unrelated to PSA recurrence inradically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res 2011;17:5878-88.
    • (2011) Clin Cancer Res , vol.17 , pp. 5878-5888
    • Minner, S.1    Enodien, M.2    Sirma, H.3    Luebke, A.M.4    Krohn, A.5    Mayer, P.S.6
  • 20
    • 84877747485 scopus 로고    scopus 로고
    • CHD1 is a 5q21 tumor suppressor required for ERG rearrangementin prostate cancer
    • Burkhardt L, Fuchs S, Krohn A, Masser S, Mader M, Kluth M, et al. CHD1 is a 5q21 tumor suppressor required for ERG rearrangementin prostate cancer. Cancer Res 2013;73:2795-805.
    • (2013) Cancer Res , vol.73 , pp. 2795-2805
    • Burkhardt, L.1    Fuchs, S.2    Krohn, A.3    Masser, S.4    Mader, M.5    Kluth, M.6
  • 21
    • 84879947917 scopus 로고    scopus 로고
    • Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2-ERG fusions
    • Kluth M, Hesse J, Heinl A, Krohn A, Steurer S, Sirma H, et al. Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2-ERG fusions. Mod Pathol 2013; 26:975-83.
    • (2013) Mod Pathol , vol.26 , pp. 975-983
    • Kluth, M.1    Hesse, J.2    Heinl, A.3    Krohn, A.4    Steurer, S.5    Sirma, H.6
  • 22
    • 84864141538 scopus 로고    scopus 로고
    • Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer
    • Krohn A, Diedler T, Burkhardt L, Mayer PS, De Silva C, Meyer-Kornblum M, et al. Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer. Am J Pathol 2012;181:401-12.
    • (2012) Am J Pathol , vol.181 , pp. 401-412
    • Krohn, A.1    Diedler, T.2    Burkhardt, L.3    Mayer, P.S.4    De Silva, C.5    Meyer-Kornblum, M.6
  • 23
    • 84885132388 scopus 로고    scopus 로고
    • Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers
    • Krohn A, Seidel A, Burkhardt L, Bachmann F, Mader M, Grupp K, et al. Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers. J Pathol 2013;231:130-41.
    • (2013) J Pathol , vol.231 , pp. 130-141
    • Krohn, A.1    Seidel, A.2    Burkhardt, L.3    Bachmann, F.4    Mader, M.5    Grupp, K.6
  • 24
    • 77649108628 scopus 로고    scopus 로고
    • Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer
    • Minner S, Jessen B, Stiedenroth L, Burandt E, Köllermann J, Mirlacher M, et al. Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer. Clin Cancer Res 2010;16:1553-60.
    • (2010) Clin Cancer Res , vol.16 , pp. 1553-1560
    • Minner, S.1    Jessen, B.2    Stiedenroth, L.3    Burandt, E.4    Köllermann, J.5    Mirlacher, M.6
  • 25
    • 84888640328 scopus 로고    scopus 로고
    • Adenocarcinoma of the prostate with gleason score 9-10 oncore biopsy: Correlation with findings at radical prostatectomy and prognosis
    • Ellis CL, Partin AW, Han M, Epstein JI. Adenocarcinoma of the prostate with Gleason score 9-10 oncore biopsy: correlation with findings at radical prostatectomy and prognosis. J Urol 2013;190:2068-73.
    • (2013) J Urol , vol.190 , pp. 2068-2073
    • Ellis, C.L.1    Partin, A.W.2    Han, M.3    Epstein, J.I.4
  • 26
    • 0026651717 scopus 로고
    • Small subgroup of aggressive, highly proliferative prostatic carcinomas defined by p53 accumulation
    • Visakorpi T, Kallioniemi OP, Heikkinen A, Koivula T, Isola J. Small subgroup of aggressive, highly proliferative prostatic carcinomas defined by p53 accumulation. J Natl Cancer Inst 1992;84:883-7.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 883-887
    • Visakorpi, T.1    Kallioniemi, O.P.2    Heikkinen, A.3    Koivula, T.4    Isola, J.5
  • 27
    • 84891736053 scopus 로고    scopus 로고
    • High nuclear karyopherin alpha 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy
    • Grupp K, Habermann M, Sirma H, Simon R, Steurer S, Hube-Magg C, et al. High nuclear karyopherin alpha 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy. Mod Pathol 2014;27:96-106.
    • (2014) Mod Pathol , vol.27 , pp. 96-106
    • Grupp, K.1    Habermann, M.2    Sirma, H.3    Simon, R.4    Steurer, S.5    Hube-Magg, C.6
  • 28
    • 0031768809 scopus 로고    scopus 로고
    • Immediate early response of the p62 gene encoding a non-proteasomal multiubiquitin chain binding protein
    • Lee YH, Ko J, Joung I, Kim JH, Shin J. Immediate early response of the p62 gene encoding a non-proteasomal multiubiquitin chain binding protein. FEBS Lett 1998;438:297-300.
    • (1998) FEBS Lett , vol.438 , pp. 297-300
    • Lee, Y.H.1    Ko, J.2    Joung, I.3    Kim, J.H.4    Shin, J.5
  • 29
    • 66449099090 scopus 로고    scopus 로고
    • Autophagy suppresses tumorigenesis through elimination of p62
    • Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009;137:1062-75.
    • (2009) Cell , vol.137 , pp. 1062-1075
    • Mathew, R.1    Karp, C.M.2    Beaudoin, B.3    Vuong, N.4    Chen, G.5    Chen, H.Y.6
  • 31
    • 84873740471 scopus 로고    scopus 로고
    • The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
    • Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, McEvoy A, et al. The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene 2013;32: 699-712.
    • (2013) Oncogene , vol.32 , pp. 699-712
    • Galavotti, S.1    Bartesaghi, S.2    Faccenda, D.3    Shaked-Rabi, M.4    Sanzone, S.5    McEvoy, A.6
  • 32
  • 33
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark JP, Cooper CS. ETS gene fusions in prostate cancer. Nat Rev Urol 2009;6:429-39.
    • (2009) Nat Rev Urol , vol.6 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 34
    • 84904057750 scopus 로고    scopus 로고
    • The prognostic impact of high nijmegen breakage syndrome (NBS1) gene expression in ERG negative prostate cancers lacking PTEN deletion isdriven by KPNA2 expression
    • Grupp K, Boumesli R, Tsourlakis MC, Koop C, Wilczak W, Adam M, et al. The prognostic impact of high Nijmegen breakage syndrome (NBS1) gene expression in ERG negative prostate cancers lacking PTEN deletion isdriven by KPNA2 expression. Int J Cancer 2014;135:1399-407.
    • (2014) Int J Cancer , vol.135 , pp. 1399-1407
    • Grupp, K.1    Boumesli, R.2    Tsourlakis, M.C.3    Koop, C.4    Wilczak, W.5    Adam, M.6
  • 35
    • 84879421374 scopus 로고    scopus 로고
    • Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers
    • Stumm L, Burkhardt L, Steurer S, Simon R, Adam M, Becker A, et al. Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers. J Clin Pathol 2013;66:563-8.
    • (2013) J Clin Pathol , vol.66 , pp. 563-568
    • Stumm, L.1    Burkhardt, L.2    Steurer, S.3    Simon, R.4    Adam, M.5    Becker, A.6
  • 36
    • 84888003158 scopus 로고    scopus 로고
    • High lysophosphatidylcholine acyltransferase 1 expression independently predicts high risk for biochemical recurrence in prostate cancers
    • Grupp K, Sanader S, Sirma H, Simon R, Koop C, Prien K, et al. High lysophosphatidylcholine acyltransferase 1 expression independently predicts high risk for biochemical recurrence in prostate cancers. Mol Oncol 2013;7:1001-11.
    • (2013) Mol Oncol , vol.7 , pp. 1001-1011
    • Grupp, K.1    Sanader, S.2    Sirma, H.3    Simon, R.4    Koop, C.5    Prien, K.6
  • 38
    • 84880863625 scopus 로고    scopus 로고
    • Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability
    • Belaid A, Cerezo M, Chargui A, Corcelle-Termeau E, Pedeutour F, Giuliano S, et al. Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res 2013; 73:4311-22.
    • (2013) Cancer Res , vol.73 , pp. 4311-4322
    • Belaid, A.1    Cerezo, M.2    Chargui, A.3    Corcelle-Termeau, E.4    Pedeutour, F.5    Giuliano, S.6
  • 40
    • 84906906535 scopus 로고    scopus 로고
    • Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis
    • Valencia T, Kim JY, Abu-Baker S, Moscat-Pardos J, Ahn CS, Reina-Campos M, et al. Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis. Cancer Cell 2014;26:121-35.
    • (2014) Cancer Cell , vol.26 , pp. 121-135
    • Valencia, T.1    Kim, J.Y.2    Abu-Baker, S.3    Moscat-Pardos, J.4    Ahn, C.S.5    Reina-Campos, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.