Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Hu, Dong ^a,b   Gur, Mert ^a   Zhou, Zhuan ^a,b   Gamper, Armin ^a,b   Hung, Mien Chie ^c,d   Fujita, Naoya ^e   Lan, Li ^a   Bahar, Ivet ^a   Wan, Yong ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; KRUPPEL LIKE FACTOR 4; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; PROTEIN BAX; PROTEIN P21; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; KRUPPEL LIKE FACTOR; PRMT5 PROTEIN, HUMAN;

APOPTOSIS; CANCER; CARCINOGEN; DNA; GENE EXPRESSION; GENOME; GENOTOXICITY; METHYLATION; MUTATION; PROTEIN; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CARCINOGENESIS; CANCER GROWTH; CATALYSIS; CELL CYCLE ARREST; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DNA BINDING; FEMALE; GENETIC ASSOCIATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN METHYLATION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; BREAST TUMOR; CARCINOGENESIS; CHEMISTRY; DNA DAMAGE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METHYLATION; PATHOLOGY; TUMOR CELL LINE;

AMINO ACID MOTIFS; ARGININE; BREAST NEOPLASMS; CARCINOGENESIS; CELL LINE, TUMOR; DNA DAMAGE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; METHYLATION; PROTEIN-ARGININE N-METHYLTRANSFERASES; UBIQUITINATION;

EID: 84942918396     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9419     Document Type: Article

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