Glioblastoma-derived macrophage colony-stimulating factor (MCSF) induces microglial release of insulin-like growth factor-binding protein 1 (IGFBP1) to promote angiogenesis

Journal of Biological Chemistry

Volumn 290, Issue 38, 2015, Pages 23401-23415

  Nijaguna, Mamatha Bangalore ^a   Patil, Vikas ^a   Urbach, Serge ^b,c,d   Shwetha, Shivayogi D ^e   Sravani, Kotha ^e   Hegde, Alangar S ^f   Chandramouli, Bangalore A ^e   Arivazhagan, Arimappamagan ^e   Marin, Philippe ^b,c,d   Santosh, Vani ^e   Somasundaram, Kumaravel ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b CNRS   (France)

^c INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^d UNIV MONTPELLIER   (France)

^e NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^f SRI SATHYA SAI INSTITUTE OF HIGHER MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINS; BODY FLUIDS; CELL CULTURE; CELLS; CYTOLOGY; DIAGNOSIS; INSULIN; MACROPHAGES; MOLECULAR BIOLOGY; PROTEINS; TUMORS;

HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-1; MACROPHAGE COLONY STIMULATING FACTORS; MOLECULAR DETERMINANTS; QUANTITATIVE PROTEOMICS; SPLEEN TYROSINE KINASE; STABLE-ISOTOPE LABELING; TUMOR-STROMA INTERACTIONS;

ENDOTHELIAL CELLS;

AMINO ACID DERIVATIVE; COLONY STIMULATING FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE SYK; SOMATOMEDIN BINDING PROTEIN 1; IGFBP1 PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; TUMOR PROTEIN;

ARTICLE; AUTOCRINE EFFECT; CELL POLARITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GLIOBLASTOMA; GLIOMA CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROGLIA; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM; TUMOR VASCULARIZATION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; ADULT; BRAIN TUMOR; FEMALE; GENETICS; MALE; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADULT; BRAIN NEOPLASMS; CELL LINE, TUMOR; FEMALE; GLIOBLASTOMA; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGE COLONY-STIMULATING FACTOR; MALE; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

EID: 84942906491     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.664037     Document Type: Article

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