메뉴 건너뛰기




Volumn 75, Issue 14, 2015, Pages 2851-2862

Enhanced MET translation and signaling sustains K-Ras-driven proliferation under anchorage-independent growth conditions

Author keywords

[No Author keywords available]

Indexed keywords

K RAS PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SCATTER FACTOR RECEPTOR;

EID: 84942906071     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-1623     Document Type: Article
Times cited : (50)

References (41)
  • 3
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • Schubbert S, Shannon K, Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 2007; 7: 295-308.
    • (2007) Nat Rev Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 4
    • 77957948992 scopus 로고    scopus 로고
    • Molecular predictive and prognostic markers in colon cancer
    • Winder T, Lenz HJ. Molecular predictive and prognostic markers in colon cancer. Cancer Treat Rev 2010; 36: 550-6.
    • (2010) Cancer Treat Rev , vol.36 , pp. 550-556
    • Winder, T.1    Lenz, H.J.2
  • 5
    • 69249161778 scopus 로고    scopus 로고
    • Biological and clinical features in predicting efficacy of epidermal growth factor receptor tyrosine kinase inhibitors: A systematic review and meta-analysis
    • Garassino MC, Borgonovo K, Rossi A, Mancuso A, Martelli O, Tinazzi A, et al. Biological and clinical features in predicting efficacy of epidermal growth factor receptor tyrosine kinase inhibitors: a systematic review and meta-analysis. Anticancer Res 2009; 29: 2691-701.
    • (2009) Anticancer Res , vol.29 , pp. 2691-2701
    • Garassino, M.C.1    Borgonovo, K.2    Rossi, A.3    Mancuso, A.4    Martelli, O.5    Tinazzi, A.6
  • 6
    • 0034548724 scopus 로고    scopus 로고
    • Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines
    • Bernhard EJ, Stanbridge EJ, Gupta S, Gupta AK, Soto D, Bakanauskas VJ, et al. Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines. Cancer Res 2000; 60: 6597-600.
    • (2000) Cancer Res , vol.60 , pp. 6597-6600
    • Bernhard, E.J.1    Stanbridge, E.J.2    Gupta, S.3    Gupta, A.K.4    Soto, D.5    Bakanauskas, V.J.6
  • 7
    • 0023901469 scopus 로고
    • Increased resistance to cis-diamminedichloroplatinum(II) in NIH 3T3 cells transformed by ras oncogenes
    • Sklar MD Increased resistance to cis-diamminedichloroplatinum(II) in NIH 3T3 cells transformed by ras oncogenes. Cancer Res 1988; 48: 793-7.
    • (1988) Cancer Res , vol.48 , pp. 793-797
    • Sklar, M.D.1
  • 8
    • 20544455590 scopus 로고    scopus 로고
    • Vinorelbine plus cisplatin vs. Observation in resected non-small-cell lung cancer
    • Winton T, Livingston R, Johnson D, Rigas J, Johnston M, Butts C, et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N Engl J Med 2005; 352: 2589-97.
    • (2005) N Engl J Med , vol.352 , pp. 2589-2597
    • Winton, T.1    Livingston, R.2    Johnson, D.3    Rigas, J.4    Johnston, M.5    Butts, C.6
  • 9
    • 84878981521 scopus 로고    scopus 로고
    • Prognostic value of KRAS mutations in patients with non-small cell lung cancer: A systematic review with meta-analysis
    • Meng D, Yuan M, Li X, Chen L, Yang J, Zhao X, et al. Prognostic value of KRAS mutations in patients with non-small cell lung cancer: a systematic review with meta-analysis. Lung Cancer 2013; 81: 1-10.
    • (2013) Lung Cancer , vol.81 , pp. 1-10
    • Meng, D.1    Yuan, M.2    Li, X.3    Chen, L.4    Yang, J.5    Zhao, X.6
  • 11
    • 84863116014 scopus 로고    scopus 로고
    • Effect of KRAS oncogene substitutions on protein behavior: Implications for signaling and clinical outcome
    • Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, et al. Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. J Natl Cancer Inst 2012; 104: 228-39.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 228-239
    • Ihle, N.T.1    Byers, L.A.2    Kim, E.S.3    Saintigny, P.4    Lee, J.J.5    Blumenschein, G.R.6
  • 12
    • 19944430434 scopus 로고    scopus 로고
    • The role of RAS oncogene in survival of patients with lung cancer: Asystematic review of the literature with meta-analysis
    • Mascaux C, Iannino N, Martin B, Paesmans M, Berghmans T, Dusart M, et al. The role of RAS oncogene in survival of patients with lung cancer: asystematic review of the literature with meta-analysis. Br J Cancer 2005; 92: 131-9.
    • (2005) Br J Cancer , vol.92 , pp. 131-139
    • Mascaux, C.1    Iannino, N.2    Martin, B.3    Paesmans, M.4    Berghmans, T.5    Dusart, M.6
  • 13
    • 84888640423 scopus 로고    scopus 로고
    • Drug discovery: Pocket of opportunity
    • Bollag G, Zhang C. Drug discovery: pocket of opportunity. Nature 2013; 503: 475-6.
    • (2013) Nature , vol.503 , pp. 475-476
    • Bollag, G.1    Zhang, C.2
  • 14
    • 57349194139 scopus 로고    scopus 로고
    • Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
    • Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, et al. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med 2008; 14: 1351-6.
    • (2008) Nat Med , vol.14 , pp. 1351-1356
    • Engelman, J.A.1    Chen, L.2    Tan, X.3    Crosby, K.4    Guimaraes, A.R.5    Upadhyay, R.6
  • 16
    • 80555157475 scopus 로고    scopus 로고
    • Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers
    • Ebi H, Corcoran RB, Singh A, Chen Z, Song Y, Lifshits E, et al. Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers. J Clin Invest 2011; 121: 4311-21.
    • (2011) J Clin Invest , vol.121 , pp. 4311-4321
    • Ebi, H.1    Corcoran, R.B.2    Singh, A.3    Chen, Z.4    Song, Y.5    Lifshits, E.6
  • 17
    • 65649108558 scopus 로고    scopus 로고
    • A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival
    • Singh A, Greninger P, Rhodes D, Koopman L, Violette S, Bardessy N, et al. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. Cancer Cell 2009; 15: 489-500.
    • (2009) Cancer Cell , vol.15 , pp. 489-500
    • Singh, A.1    Greninger, P.2    Rhodes, D.3    Koopman, L.4    Violette, S.5    Bardessy, N.6
  • 18
    • 79953756460 scopus 로고    scopus 로고
    • Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
    • Collisson EA, Sadanandam A, Olson P, Gibb WJ, Truitt M, Gu S, et al. Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nat Med 2011; 17: 500-3.
    • (2011) Nat Med , vol.17 , pp. 500-503
    • Collisson, E.A.1    Sadanandam, A.2    Olson, P.3    Gibb, W.J.4    Truitt, M.5    Gu, S.6
  • 19
    • 60149095359 scopus 로고    scopus 로고
    • Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo
    • Shi XH, Liang ZY, Ren XY, Liu TH. Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo. Cancer Gene Ther 2009; 16: 227-36.
    • (2009) Cancer Gene Ther , vol.16 , pp. 227-236
    • Shi, X.H.1    Liang, Z.Y.2    Ren, X.Y.3    Liu, T.H.4
  • 20
    • 84865620351 scopus 로고    scopus 로고
    • K-RAS mutant pancreatic tumors show higher sensitivitytoMEKthantoPI3K inhibition in vivo
    • Hofmann I, Weiss A, Elain G, Schwaederle M, Sterker D, Romanet V, et al. K-RAS mutant pancreatic tumors show higher sensitivitytoMEKthantoPI3K inhibition in vivo. PLoS One 2012; 7: e44146.
    • (2012) PLoS One , vol.7
    • Hofmann, I.1    Weiss, A.2    Elain, G.3    Schwaederle, M.4    Sterker, D.5    Romanet, V.6
  • 21
    • 33846973375 scopus 로고    scopus 로고
    • Knockdown of mutant K-ras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells
    • Zhang Z, Jiang G, Yang F, Wang J. Knockdown of mutant K-ras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells. Cancer Biol Ther 2006; 5: 1481-6.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1481-1486
    • Zhang, Z.1    Jiang, G.2    Yang, F.3    Wang, J.4
  • 22
    • 59649109230 scopus 로고    scopus 로고
    • Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab
    • Pickl M, Ries CH. Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab. Oncogene 2009; 28: 461-8.
    • (2009) Oncogene , vol.28 , pp. 461-468
    • Pickl, M.1    Ries, C.H.2
  • 23
    • 77953540958 scopus 로고    scopus 로고
    • HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
    • Weigelt B, Lo AT, Park CC, Gray JW, Bissell MJ. HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat 2010; 122: 35-43.
    • (2010) Breast Cancer Res Treat , vol.122 , pp. 35-43
    • Weigelt, B.1    Lo, A.T.2    Park, C.C.3    Gray, J.W.4    Bissell, M.J.5
  • 24
    • 34248650697 scopus 로고    scopus 로고
    • The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
    • Kenny PA, Lee GY, Myers CA, Neve RM, Semeiks JR, Spellman PT, et al. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol 2007; 1: 84-96.
    • (2007) Mol Oncol , vol.1 , pp. 84-96
    • Kenny, P.A.1    Lee, G.Y.2    Myers, C.A.3    Neve, R.M.4    Semeiks, J.R.5    Spellman, P.T.6
  • 25
    • 79952236235 scopus 로고    scopus 로고
    • Pancreatic cancer spheres are more than just aggregates of stem markerpositive cells
    • Gaviraghi M, Tunici P, Valensin S, Rossi M, Giordano C, Magnoni L, et al. Pancreatic cancer spheres are more than just aggregates of stem markerpositive cells. Biosci Rep 2011; 31: 45-55.
    • (2011) Biosci Rep , vol.31 , pp. 45-55
    • Gaviraghi, M.1    Tunici, P.2    Valensin, S.3    Rossi, M.4    Giordano, C.5    Magnoni, L.6
  • 26
    • 84861733799 scopus 로고    scopus 로고
    • MET: A promising anticancer therapeutic target
    • Peters S, Adjei AA. MET: a promising anticancer therapeutic target. Nat Rev Clin Oncol 2012; 9: 314-26.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 314-326
    • Peters, S.1    Adjei, A.A.2
  • 28
    • 17344381429 scopus 로고    scopus 로고
    • Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
    • Schmidt L, Duh FM, Chen F, Kishida T, Glenn G, Choyke P, et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 1997; 16: 68-73.
    • (1997) Nat Genet , vol.16 , pp. 68-73
    • Schmidt, L.1    Duh, F.M.2    Chen, F.3    Kishida, T.4    Glenn, G.5    Choyke, P.6
  • 29
    • 84864286442 scopus 로고    scopus 로고
    • Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
    • Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature 2012: 487: 505-9.
    • (2012) Nature , vol.487 , pp. 505-509
    • Wilson, T.R.1    Fridlyand, J.2    Yan, Y.3    Penuel, E.4    Burton, L.5    Chan, E.6
  • 30
    • 84877848587 scopus 로고    scopus 로고
    • Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition
    • Katayama R, Aoyama A, Yamori T, Qi J, Oh-hara T, Song Y, et al. Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition. Cancer Res 2013; 73: 3087-96.
    • (2013) Cancer Res , vol.73 , pp. 3087-3096
    • Katayama, R.1    Aoyama, A.2    Yamori, T.3    Qi, J.4    Oh-Hara, T.5    Song, Y.6
  • 32
    • 84863229979 scopus 로고    scopus 로고
    • Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer
    • Li Y, Fan S, Koo J, Yue P, Chen ZG, Owonikoko TK, et al. Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer. Cancer Biol Ther 2012; 13: 272-80.
    • (2012) Cancer Biol Ther , vol.13 , pp. 272-280
    • Li, Y.1    Fan, S.2    Koo, J.3    Yue, P.4    Chen, Z.G.5    Owonikoko, T.K.6
  • 34
    • 81855194258 scopus 로고    scopus 로고
    • c-Met is a marker of pancreatic cancer stem cells and therapeutic target
    • Li C, Wu JJ, Hynes M, Dosch J, Sarkar B, Welling TH, et al. c-Met is a marker of pancreatic cancer stem cells and therapeutic target. Gastroenterology 2011; 141: 2218-27.
    • (2011) Gastroenterology , vol.141 , pp. 2218-2227
    • Li, C.1    Wu, J.J.2    Hynes, M.3    Dosch, J.4    Sarkar, B.5    Welling, T.H.6
  • 35
    • 0026655776 scopus 로고
    • Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor
    • Rong S, Bodescot M, Blair D, Dunn J, Nakamura T, Mizuno K, et al. Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol 1992; 12: 5152-8.
    • (1992) Mol Cell Biol , vol.12 , pp. 5152-5158
    • Rong, S.1    Bodescot, M.2    Blair, D.3    Dunn, J.4    Nakamura, T.5    Mizuno, K.6
  • 36
    • 84882629652 scopus 로고    scopus 로고
    • EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis
    • Breindel JL, Haskins JW, Cowell EP, Zhao M, Nguyen DX, Stern DF. EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res 2013; 73: 5053-65.
    • (2013) Cancer Res , vol.73 , pp. 5053-5065
    • Breindel, J.L.1    Haskins, J.W.2    Cowell, E.P.3    Zhao, M.4    Nguyen, D.X.5    Stern, D.F.6
  • 37
    • 0034649157 scopus 로고    scopus 로고
    • Increase in cap- and IRES-dependent protein synthesis by overproduction of translation initiation factor eIF4G
    • Hayashi S, Nishimura K, Fukuchi-Shimogori T, Kashiwagi K, Igarashi K. Increase in cap- and IRES-dependent protein synthesis by overproduction of translation initiation factor eIF4G. Biochem Biophys Res Commun 2000; 277: 117-23.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 117-123
    • Hayashi, S.1    Nishimura, K.2    Fukuchi-Shimogori, T.3    Kashiwagi, K.4    Igarashi, K.5
  • 38
    • 67650080623 scopus 로고    scopus 로고
    • Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer
    • Silvera D, Arju R, Darvishian F, Levine PH, Zolfaghari L, Goldberg J, et al. Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer. Nat Cell Biol 2009; 11: 903-8.
    • (2009) Nat Cell Biol , vol.11 , pp. 903-908
    • Silvera, D.1    Arju, R.2    Darvishian, F.3    Levine, P.H.4    Zolfaghari, L.5    Goldberg, J.6
  • 39
    • 84871292666 scopus 로고    scopus 로고
    • The soy isoflavone equol may increase cancer malignancy via upregulation of eukaryotic protein synthesis initiation factor eIF4G
    • de la Parra C, Otero-Franqui E, Martinez-Montemayor M, Dharmawardhane S. The soy isoflavone equol may increase cancer malignancy via upregulation of eukaryotic protein synthesis initiation factor eIF4G. J Biol Chem 2012; 287: 41640-50.
    • (2012) J Biol Chem , vol.287 , pp. 41640-41650
    • De La Parra, C.1    Otero-Franqui, E.2    Martinez-Montemayor, M.3    Dharmawardhane, S.4
  • 41
    • 0033200316 scopus 로고    scopus 로고
    • Translation driven by an eIF4G core domain in vivo
    • De Gregorio E, Preiss T, Hentze MW. Translation driven by an eIF4G core domain in vivo. EMBO J 1999; 18: 4865-74.
    • (1999) EMBO J , vol.18 , pp. 4865-4874
    • De Gregorio, E.1    Preiss, T.2    Hentze, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.