Experimental Null Method to Guide the Development of Technical Procedures and to Control False-Positive Discovery in Quantitative Proteomics

Journal of Proteome Research

Volumn 14, Issue 10, 2015, Pages 4147-4157

  Shen, Xiaomeng ^a,b   Hu, Qiang ^c   Li, Jun ^b   Wang, Jianmin ^c   Qu, Jun ^a,b  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

experimental null (EN); false altered proteins discovery rate (FADR); ion current based quantification; quantitative proteomics

Indexed keywords

ACCURACY; ANALYTIC METHOD; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DATA PROCESSING; EXPERIMENTAL NULL METHOD; FALSE ALTERED PROTEINS DISCOVERY RATE; FALSE POSITIVE RESULT; HUMAN; HUMAN CELL; NONHUMAN; PILOT STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE ANALYSIS; RAT; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SAMPLE SIZE; ANIMAL; ARTIFACT; BRAIN; BRAIN CHEMISTRY; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LIQUID CHROMATOGRAPHY; LIVER; METABOLISM; MONONUCLEAR CELL; PROCEDURES; STANDARD; TANDEM MASS SPECTROMETRY;

BIOLOGICAL MARKER; PROTEOME;

ANIMALS; ARTIFACTS; BIOMARKERS; BRAIN; BRAIN CHEMISTRY; CHROMATOGRAPHY, LIQUID; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LEUKOCYTES, MONONUCLEAR; LIVER; PROTEOME; PROTEOMICS; RATS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84942895846     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00200     Document Type: Article

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