Phosphoregulation of Cardiac Inotropy via Myosin Binding Protein-C during Increased Pacing Frequency or β1-Adrenergic Stimulation

Circulation: Heart Failure

Volumn 8, Issue 3, 2015, Pages 595-604

  Tong, Carl W ^a,b,c   Wu, Xin ^b   Liu, Yang ^b   Rosas, Paola C ^b   Sadayappan, Sakthivel ^d   Hudmon, Andy ^e   Muthuchamy, Mariappan ^b   Powers, Patricia A ^a   Valdivia, Héctor H ^f   Moss, Richard L ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

^c SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^d LOYOLA UNIVERSITY CHICAGO   (United States)

^e INDIANA UNIVERSITY   (United States)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

contractility; myosin binding protein C; phosphorylation

Indexed keywords

ALANINE; CALCIUM ION; CARDIAC MYOSIN; MYOSIN BINDING PROTEIN C; SERINE; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CAMK2D PROTEIN, MOUSE; CARDIOTONIC AGENT; CARRIER PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; MYOSIN-BINDING PROTEIN C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; BETA ADRENERGIC STIMULATION 1; CARDIAC INOTROPY; CONFORMATIONAL TRANSITION; FREQUENCY ANALYSIS; HEART FAILURE; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART PACING; HEART PAPILLARY MUSCLE; INOTROPISM; MOUSE; MUSCLE TWITCH; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TISSUE DOPPLER IMAGING; ANIMAL; CALCIUM SIGNALING; DRUG EFFECTS; ENZYME ACTIVATION; GENETICS; GENOTYPE; HEART CONTRACTION; KINETICS; METABOLISM; MUSCLE STRENGTH; MUTATION; PHENOTYPE; PHOSPHORYLATION; PROTEIN PROCESSING; TRANSGENIC MOUSE;

ADRENERGIC BETA-1 RECEPTOR AGONISTS; ANIMALS; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIAC PACING, ARTIFICIAL; CARDIOTONIC AGENTS; CARRIER PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GENOTYPE; KINETICS; MICE, TRANSGENIC; MUSCLE STRENGTH; MUTATION; MYOCARDIAL CONTRACTION; PAPILLARY MUSCLES; PHENOTYPE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84942883952     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.114.001585     Document Type: Article

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