Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals

Journal of Controlled Release

Volumn 217, Issue , 2015, Pages 243-255

  Bagalkot, Vaishali ^a   Badgeley, Marcus A ^b,c   Kampfrath, Thomas ^b,d   Deiuliis, Jeffrey A ^a,b   Rajagopalan, Sanjay ^a,b   Maiseyeu, Andrei ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d SANTA CLARA VALLEY MEDICAL CENTER   (United States)

Author keywords

Atherosclerosis; Inflammation; Intravital imaging; Magnetic resonance imaging; Obesity; Theranostic nanoparticles

Indexed keywords

DISEASES; ENERGY TRANSFER; HYDROPHOBICITY; MACROPHAGES; MAMMALS; NANOMAGNETICS; NANOPARTICLES; NUTRITION; PARTICLE BEAMS; RESONANCE; TISSUE;

ANTI-INFLAMMATORY DRUGS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; INFLAMMATION; MECHANISM AND KINETICS; OBESITY; PHENOTYPIC PLASTICITY; RESONANCE ENERGY TRANSFER;

MAGNETIC RESONANCE IMAGING;

GADOLINIUM PENTETATE BIS(STERYLAMIDE); GADOLINIUM PENTETATE DERIVATIVE; LIPID LATEX NANOPARTICLE; NANOCARRIER; PACLITAXEL; PHOSPHOLIPASE A2; PHOSPHOLIPID; POLYSTYRENE DERIVATIVE; ROSIGLITAZONE; TAMOXIFEN; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIINFLAMMATORY AGENT; APOLIPOPROTEIN E; CHOLESTEROL; CYTOKINE; FLUORESCEIN ISOTHIOCYANATE; GADOLINIUM; MACROGOL DERIVATIVE; NANOPARTICLE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; POLYSTYRENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL PHAGOCYTOSIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIET INDUCED OBESITY; DRUG BINDING; DRUG CLEARANCE; DRUG HALF LIFE; ELECTRON MICROSCOPY; ENERGY TRANSFER; ENZYME ACTIVITY; EXPERIMENTAL ATHEROSCLEROSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; INFLAMMATORY MACROPHAGE; LIGHT SCATTERING; MACROPHAGE; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SURFACE PROPERTY; TIME LAPSE IMAGING; ANALOGS AND DERIVATIVES; ANIMAL; ATHEROSCLEROSIS; C57BL MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; OBESITY; PHAGOCYTOSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELL LINE; CHOLESTEROL; CYTOKINES; FLUORESCEIN-5-ISOTHIOCYANATE; GADOLINIUM; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; NANOPARTICLES; OBESITY; PACLITAXEL; PHAGOCYTOSIS; PHOSPHATIDYLETHANOLAMINES; PHOSPHATIDYLSERINES; PHOSPHOLIPASES A2; POLYETHYLENE GLYCOLS; POLYSTYRENES; TAMOXIFEN; THIAZOLIDINEDIONES;

EID: 84942870944     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.09.027     Document Type: Article

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