New strategy for diagnosing embryo implantation potential by combining proteomics and time-lapse technologies

Fertility and Sterility

Volumn 104, Issue 4, 2015, Pages 908-914

  Dominguez, Francisco ^a,b   Meseguer, Marcos ^b,c   Aparicio Ruiz, Belen ^c   Piqueras, Paloma ^c   Quiñonero, Alicia ^a   Simón, Carlos ^a,b,c,d  

^a INSTITUTO VALENCIANO DE INFERTILIDAD   (Spain)

^b Instituto Universitario IVI INCLIVA   (Spain)

^c IVI Valencia   (Spain)

^d STANFORD UNIVERSITY   (United States)

Author keywords

blastocyst; Embryo kinetics; IL 6; implantation potential; proteomics; time lapse

Indexed keywords

ALPHA2 INTERFERON; CXCL13 CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; PLACENTAL GROWTH FACTOR; PLACENTAL GROWTH FACTOR 1; PROTEOME; STEM CELL FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

5 BLASTOMERE CLEAVAGE; ADULT; ARTICLE; BLASTOCYST; BLASTOMERE SYNCHRONY; CELL CYCLE; CLINICAL ARTICLE; CLINICAL CLASSIFICATION; COHORT ANALYSIS; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; EMBRYO SELECTION; FEMALE; FEMALE INFERTILITY; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; NIDATION; OOCYTE CLEAVAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RETROSPECTIVE STUDY; TIME LAPSE IMAGING; VIDEORECORDING; ANIMAL EMBRYO; CASE CONTROL STUDY; CELL CULTURE; CYTOLOGY; EMBRYO CULTURE; EMBRYO TRANSFER; EVALUATION STUDY; INFERTILITY, FEMALE; METABOLISM; PATHOLOGY; PREDICTIVE VALUE; PREGNANCY; PRENATAL DIAGNOSIS; PROCEDURES; PROGNOSIS;

ADULT; CASE-CONTROL STUDIES; CELLS, CULTURED; EMBRYO CULTURE TECHNIQUES; EMBRYO IMPLANTATION; EMBRYO TRANSFER; EMBRYO, MAMMALIAN; FEMALE; HUMANS; INFERTILITY, FEMALE; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREIMPLANTATION DIAGNOSIS; PROGNOSIS; PROTEOMICS; RETROSPECTIVE STUDIES; SPERM INJECTIONS, INTRACYTOPLASMIC; TIME-LAPSE IMAGING;

EID: 84942816318     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2015.06.032     Document Type: Article

References (32)

1. D.K. Gardner, M. Meseguer, C. Rubio, and N.R. Treff Diagnosis of human preimplantation embryo viability Hum Reprod Update 2015 Jan 6 pii: dmu064
2. G.A. Thouas, F. Dominguez, M.P. Green, F. Vilella, C. Simon, and D.K. Gardner Soluble ligands and their receptors in human embryo development and implantation Endocr Rev 36 2015 92 130
3. B. Aparicio, M. Cruz, and M. Meseguer Is morphokinetic analysis the answer? Reprod Biomed Online 27 2013 654 663
4. N. Basile, M. Caiazzo, and M. Meseguer What does morphokinetics add to embryo selection and in-vitro fertilization outcomes? Curr Opin Obstet Gynecol 27 2015 193 200
5. K. Kirkegaard, I.E. Agerholm, and H.J. Ingerslev Time-lapse monitoring as a tool for clinical embryo assessment Hum Reprod 27 2012 1277 1285
6. M. Montag, B. Toth, and T. Strowitzki New approaches to embryo selection Reprod Biomed Online 27 2013 539 546
7. M. Cruz, B. Gadea, N. Garrido, K.S. Pedersen, M. Martínez, I. Pérez-Cano, and et al. Embryo quality, blastocyst and ongoing pregnancy rates in oocyte donation patients whose embryos were monitored by time-lapse imaging J Assist Reprod Genet 28 2011 569 573
8. K. Kirkegaard, J.J. Hindkjaer, M.L. Grøndahl, U.S. Kesmodel, and H.J. Ingerslev A randomized clinical trial comparing embryo culture in a conventional incubator with a time-lapse incubator J Assist Reprod Genet 29 2012 565 572
9. M. Meseguer, I. Rubio, M. Cruz, N. Basile, J. Marcos, and A. Requena Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study Fertil Steril 98 2012 1481 1489.e10
10. I. Rubio, R. Kuhlmann, I. Agerholm, J. Kirk, J. Herrero, M.J. Escriba, and et al. Limited implantation success of direct-cleaved human zygotes: a time-lapse study Fertil Steril 98 2012 1458 1463
11. T. Hardarson, C. Löfman, G. Coull, A. Sjögren, L. Hamberger, and R. Edwards Internalization of cellular fragments in a human embryo: time-lapse recordings Reprod Biomed Online 5 2002 36 38
12. K.A. Wirka, A.A. Chen, J. Conaghan, K. Ivani, M. Gvakharia, B. Behr, and et al. Atypical embryo phenotypes identified by time-lapse microscopy: high prevalence and association with embryo development Fertil Steril 101 2014 1637 1648.e5
13. M. Meseguer, J. Herrero, A. Tejera, K.M. Hilligsoe, N.B. Ramsing, and J. Remohi The use of morphokinetics as a predictor of embryo implantation Hum Reprod 26 2011 2658 2671
14. I. Rubio, A. Galán, Z. Larreategui, F. Ayerdi, J. Bellver, J. Herrero, and et al. Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the Embryoscope Fertil Steril 102 2014 1287 1294.e5
15. K. Hollywood, D.R. Brison, and R. Goodacre Metabolomics: current technologies and future trends Proteomics 6 2006 4716 4723
16. S.A. Butler, J. Luttoo, M.O. Freire, T.K. Abban, P.T. Borrelli, and R.K. Iles Human chorionic gonadotropin (hCG) in the secretome of cultured embryos: hyperglycosylated hCG and hCG-free beta subunit are potential markers for infertility management and treatment Reprod Sci 20 2013 1038 1045
17. L.M. Mains, L. Christenson, B. Yang, A.E. Sparks, S. Mathur, and B.J. van Voorhis Identification of apolipoprotein A1 in the human embryonic secretome Fertil Steril 96 2011 422 427.e2
18. I. Noci, B. Fuzzi, R. Rizzo, L. Melchiorri, L. Criscuoli, S. Dabizzi, and et al. Embryonic soluble HLA-G as a marker of developmental potential in embryos Hum Reprod 20 2005 138 146
19. S. Ziebe, A. Loft, B.B. Povlsen, K. Erb, I. Agerholm, M. Aasted, and et al. A randomized clinical trial to evaluate the effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) in embryo culture medium for in vitro fertilization Fertil Steril 99 2013 1600 1609
20. R.R. Saith, N.A. Bersinger, D.H. Barlow, and I.L. Sargent The role of pregnancy-specific beta-1 glycoprotein (SP1) in assessing the human blastocyst quality in vitro Hum Reprod 11 1996 1038 1042
21. K.P. Jones, S.H. Warnock, R.L. Urry, S.S. Edwin, and M.D. Mitchell Immunosuppressive activity and alpha interferon concentrations in human embryo culture media as an index of potential for successful implantation Fertil Steril 57 1992 637 640
22. U. Punjabi, A. Vereecken, L. Delbeke, M. Angle, M. Gielis, J. Gerris, and et al. Embryo-derived platelet activating factor, a marker of embryo quality and viability following ovarian stimulation for in vitro fertilization J In Vitro Fert Embryo Transf 7 1990 321 326
23. S.S. Cortezzi, J.S. Garcia, C.R. Ferreira, D.P. Braga, R.C. Figueira, A. Iaconelli Jr., and et al. Secretome of the preimplantation human embryo by bottom-up label-free proteomics Anal Bioanal Chem 401 2011 1331 1339
24. S.S. Cortezzi, E.C. Cabral, M.G. Trevisan, C.R. Ferreira, A.S. Setti, D.P. Braga, and et al. Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium Reproduction 145 2013 453 462
25. F. Dominguez, B. Gadea, F.J. Esteban, J.A. Horcajadas, A. Pellicer, and C. Simon Comparative protein-profile analysis of implanted versus nonimplanted human blastocysts Hum Reprod 23 2008 1993 2000
26. N. Garrido, J.L. Zuzuarregui, M. Meseguer, C. Simon, J. Remohi, and A. Pellicer Sperm and oocyte donor selection and management: experience of a 10 year follow-up of more than 2100 candidates Hum Reprod 17 2002 3142 3148
27. S. García-Herrero, N. Garrido, J.A. Martínez-Conejero, J. Remohí, A. Pellicer, and M. Meseguer Differential transcriptomic profile in spermatozoa achieving pregnancy or not via ICSI Reprod Biomed Online 22 2011 25 36
28. M. Alikani, G. Calderon, G. Tomkin, J. Garrisi, M. Kokot, and J. Cohen Cleavage anomalies in early human embryos and survival after prolonged culture in-vitro Hum Reprod 15 2000 2634 2643
29. A. Cobo, M. Meseguer, J. Remohi, and A. Pellicer Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial Hum Reprod 25 2010 2239 2246
30. F. Dominguez, A. Pellicer, and C. Simon The human embryo proteome Reprod Sci 16 2009 188 190
31. F. Dominguez, B. Gadea, A. Mercader, F.J. Esteban, A. Pellicer, and C. Simon Embryologic outcome and secretome profile of implanted blastocysts obtained after coculture in human endometrial epithelial cells versus the sequential system Fertil Steril 93 2010 774 782.e1
32. N. Basile, P. Vime, M. Florensa, B. Aparicio Ruiz, J.A. Garcia Velasco, J. Remohi, and et al. The use of morphokinetics as a predictor of implantation: a multicentric study to define and validate an algorithm for embryo selection Hum Reprod 30 2015 276 283