Is morphokinetic analysis the answer?

Reproductive BioMedicine Online

Volumn 27, Issue 6, 2013, Pages 654-663

  Aparicio, B ^a   Cruz, M ^a   Meseguer, M ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

assisted reproduction; cleavage; embryo; exact timing; morphokinetic parameters; time lapse

Indexed keywords

ANEUPLOIDY; ARTICLE; BLASTOCYST; BLASTOMA; CINERADIOGRAPHY; CYTOKINESIS; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; HUMAN; IMAGE ANALYSIS; IMAGE QUALITY; INFERTILITY THERAPY; INTRACYTOPLASMIC SPERM INJECTION; MITOSIS; MULTIPLE PREGNANCY; NIDATION; PLOIDY; PREGNANCY OUTCOME; PREGNANCY RATE; TIME LAPSE IMAGING; ZYGOTE;

ASSISTED REPRODUCTION; CLEAVAGE; EMBRYO; EXACT TIMING; MORPHOKINETIC PARAMETERS; TIME LAPSE;

EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; HUMANS; MOVEMENT; PREGNANCY; REPRODUCTIVE TECHNIQUES, ASSISTED; TIME-LAPSE IMAGING;

EID: 84889094212     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2013.07.017     Document Type: Review

References (52)

1. A.N. Andersen, V. Goossens, S. Bhattacharya, A. Ferraretti, M. Kupka, J. De Mouzon, and K. Nygren Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE) Hum. Reprod. 24 2009 1267 1287
2. P. Barlow, F. Puissant, P. Van der Zwalmen, J. Vandromme, P. Trigaux, and F. Leroy In vitro fertilization, development, and implantation after exposure of mature mouse oocytes to visible light Mol. Reprod. Dev. 33 1992 297 302
3. N. Basile, and M. Meseguer Time-lapse technology: evaluation of embryo quality and new markers for embryo selection Expert Rev. Obstet. Gynecol. 7 2012 175 190
4. N. Basile, D. Morbeck, J. García-Velasco, F. Bronet, and M. Meseguer Type of culture media does not affect embryo kinetics: a time-lapse analysis of sibling oocytes Hum. Reprod. 28 2013 634 641
5. J. Bedford, and A. Dobrenis Light exposure of oocytes and pregnancy rates after their transfer in the rabbit J. Reprod. Fertil. 85 1989 477 481
6. D. Blake, C. Farquhar, N. Johnson, and M. Proctor Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology Cochrane Database Syst. Rev. 4 2007
7. P.R. Braude Selecting the 'best' embryos: prospects for improvement Reprod. Biomed. Online 27 2013 644 653
8. D.R. Brison, Roberts, and S.J. Kimber How should we assess the safety of IVF technologies? Reprod. Biomed. Online 27 2013 710 721
9. A. Campbell, S. Fishel, N. Bowman, S. Duffy, M. Sedler, and C.F.L. Hickman Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokinetics Reprod. Biomed. Online 26 2013 477 485
10. A. Campbell, S. Fishel, N. Bowman, S. Duffy, M. Sedler, and S. Thornton Retrospective analysis of outcomes after IVF using an aneuploidy risk model derived from time-lapse imaging without PGS Reprod. Biomed. Online 27 2013 140 146
11. S.L. Chavez, K.E. Loewke, J. Han, F. Moussavi, P. Colls, S. Munne, B. Behr, and R.A.R. Pera Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage Nat. Commun. 3 2012 1251
12. H.N. Ciray, L. Karagenç, U. Ulug, F. Bener, and M. Bahceci Use of both early cleavage and day 2 mononucleation to predict embryos with high implantation potential in intracytoplasmic sperm injection cycles Fertil. Steril. 84 2005 1411 1416
13. M. Cruz, B. Gadea, N. Garrido, K.S. Pedersen, M. Martínez, I. Pérez-Cano, M. Muñoz, and M. Meseguer Embryo quality, blastocyst and ongoing pregnancy rates in oocyte donation patients whose embryos were monitored by time-lapse imaging J. Assist. Reprod. Genet. 28 2011 569 573
14. M. Cruz, N. Garrido, J. Herrero, I. Perez-Cano, M. Munoz, and M. Meseguer Timing of cell division in human cleavage-stage embryos is linked with blastocyst formation and quality Reprod. Biomed. Online 25 2012 371 381
15. M. Cruz, N. Garrido, B. Gadea, M. Muñoz, I. Pérez-Cano, and M. Meseguer Oocyte insemination techniques are related to alterations of embryo developmental timing in an oocyte donation model Reprod. Biomed. Online 27 2013 367 375
16. M. Dal Canto, G. Coticchio, M. Mignini Renzini, E. De Ponti, P.V. Novara, F. Brambillasca, R. Comi, and R. Fadini Cleavage kinetics analysis of human embryos predicts development to blastocyst and implantation Reprod. Biomed. Online 25 2012 474 480
17. R.G. Edwards, S.B. Fishel, J. Cohen, C.B. Fehilly, J.M. Purdy, J.M. Slater, P.C. Steptoe, and J.M. Webster Factors influencing the success of in vitro fertilization for alleviating human infertility J. In Vitro Fert. Embryo Transf. 1 1984 3 23
18. D.K. Gardner, P. Vella, M. Lane, L. Wagley, T. Schlenker, and W.B. Schoolcraft Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers Fertil. Steril. 69 1998 84 88
19. D. Glujovsky, D. Blake, C. Farquhar, and A. Bardach Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology Cochrane Libr. 2012
20. T. Hardarson, C. Löfman, G. Coull, A. Sjögren, L. Hamberger, and R. Edwards Internalization of cellular fragments in a human embryo: time-lapse recordings Reprod. Biomed. Online 5 2002 36 38
21. S. Hashimoto, N. Kato, K. Saeki, and Y. Morimoto Selection of high-potential embryos by culture in poly(dimethylsiloxane) microwells and time-lapse imaging Fertil. Steril. 97 2012 332 337
22. D. Hlinka, B. Kalatova, I. Uhrinova, S. Dolinska, J. Rutarova, J. Rezacova, S. Lazarovska, and M. Dudas Time-lapse cleavage rating predicts human embryo viability Reprod. Biomed. Online 16 2008 346 349
23. P. Holm, P. Booth, and H. Callesen Kinetics of early in vitro development of bovine in vivo-and in vitro-derived zygotes produced and/or cultured in chemically defined or serum-containing media Reproduction 123 2002 553 565
24. S. Katari, N. Turan, M. Bibikova, O. Erinle, R. Chalian, M. Foster, J.P. Gaughan, C. Coutifaris, and C. Sapienza DNA methylation and gene expression differences in children conceived in vitro or in vivo Hum. Mol. Genet. 18 2009 3769 3778
25. K. Kirkegaard, I.E. Agerholm, and H.J. Ingerslev Time-lapse monitoring as a tool for clinical embryo assessment Hum. Reprod. 27 2012 1277 1285
26. J. Lemmen, I. Agerholm, and S. Ziebe Kinetic markers of human embryo quality using time-lapse recordings of IVF/ICSI-fertilized oocytes Reprod. Biomed. Online 17 2008 385 391
27. K. Lundin, C. Bergh, and T. Hardarson Early embryo cleavage is a strong indicator of embryo quality in human IVF Hum. Reprod. 16 2001 2652 2657
28. M.C. Magli, L. Gianaroli, A.P. Ferraretti, M. Lappi, A. Ruberti, and V. Farfalli Embryo morphology and development are dependent on the chromosomal complement Fertil. Steril. 87 2007 534 541
29. M.R.W. Mann, and M.M. Denomme Maternal control of genomic imprint maintenance Reprod. Biomed. Online 27 2013 629 636
30. A. Mercader, J.A. Garcia-Velasco, E. Escudero, J. Remohí, A. Pellicer, and C. Simón Clinical experience and perinatal outcome of blastocyst transfer after coculture of human embryos with human endometrial epithelial cells: a 5-year follow-up study Fertil. Steril. 80 2003 1162
31. M. Meseguer, J. Herrero, A. Tejera, K.M. Hilligsøe, N.B. Ramsing, and J. Remohí The use of morphokinetics as a predictor of embryo implantation Hum. Reprod. 26 2011 2658 2671
32. M. Meseguer, U. Kruhne, and S. Laursen Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction? Fertil. Steril. 97 2012 1277 1286
33. M. Meseguer, I. Rubio, M. Cruz, N. Basile, J. Marcos, and A. Requena Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study Fertil. Steril. 98 2012 1481 1489e10
34. H.L. Miles, P.L. Hofman, J. Peek, M. Harris, D. Wilson, E.M. Robinson, P.D. Gluckman, and W.S. Cutfield In vitro fertilization improves childhood growth and metabolism J. Clin. Endocrinol. Metab. 92 2007 3441 3445
35. Y. Mio, and K. Maeda Time-lapse cinematography of dynamic changes occurring during in vitro development of human embryos Obstet. Gynecol. 199 2008 660 e1-660. e5
36. M. Montag, J. Liebenthron, and M. Köster Which morphological scoring system is relevant in human embryo development? Placenta 32 2011 S252 S256
37. T. Nakahara, A. Iwase, M. Goto, T. Harata, M. Suzuki, M. Ienaga, H. Kobayashi, S. Takikawa, S. Manabe, and F. Kikkawa Evaluation of the safety of time-lapse observations for human embryos J. Assist. Reprod. Genet. 27 2010 93 96
38. L.D.M. Ottosen, J. Hindkjær, and J. Ingerslev Light exposure of the ovum and preimplantation embryo during ART procedures J. Assist. Reprod. Genet. 24 2007 99 103
39. D. Payne, S.P. Flaherty, M.F. Barry, and C.D. Matthews Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography Hum. Reprod. 12 1997 532 541
40. C. Pribenszky, E. Losonczi, M. Molnár, Z. Lang, S. Mátyás, K. Rajczy, K. Molnár, P. Kovács, P. Nagy, and J. Conceicao Prediction of in-vitro developmental competence of early cleavage-stage mouse embryos with compact time-lapse equipment Reprod. Biomed. Online 20 2010 371 379
41. C. Pribenszky, S. Mátyás, P. Kovács, E. Losonczi, J. Zádori, and G. Vajta Pregnancy achieved by transfer of a single blastocyst selected by time-lapse monitoring Reprod. Biomed. Online 21 2010 533 536
42. I. Rubio, R. Kuhlmann, I. Agerholm, J. Kirk, J. Herrero, M.J. Escriba, J. Bellver, and M. Meseguer Limited implantation success of direct-cleaved human zygotes: a time-lapse study Fertil. Steril. 98 2012 1458 1463
43. D. Sakkas, Y. Shoukir, D. Chardonnens, P.G. Bianchi, and A. Campana Early cleavage of human embryos to the two-cell stage after intracytoplasmic sperm injection as an indicator of embryo viability Hum. Reprod. 13 1998 182 187
44. A. Salumets, C. Hydén-Granskog, S. Mäkinen, A.M. Suikkari, A. Tiitinen, and T. Tuuri Early cleavage predicts the viability of human embryos in elective single embryo transfer procedures Hum. Reprod. 18 2003 821 825
45. L. Scott, A. Finn, T. O'Leary, S. McLellan, and J. Hill Morphologic parameters of early cleavage-stage embryos that correlate with fetal development and delivery: prospective and applied data for increased pregnancy rates Hum. Reprod. 22 2007 230 240
46. Y. Shoukir, A. Campana, T. Farley, and D. Sakkas Early cleavage of in-vitro fertilized human embryos to the 2-cell stage: a novel indicator of embryo quality and viability Hum. Reprod. 12 1997 1531 1536
47. P. Steptoe, and R.G. Edwards Birth after the reimplantation of a human embryo Lancet 2 1978 366
48. M.C. Summers, and J.D. Biggers Chemically defined media and the culture of mammalian preimplantation embryos: historical perspective and current issues Hum. Reprod. Update 9 2003 557 582
49. M. Takenaka, T. Horiuchi, and R. Yanagimachi Effects of light on development of mammalian zygotes Proc. Natl. Acad. Sci. 104 2007 14289 14293
50. M.C. Walker, K.E. Murphy, S. Pan, Q. Yang, and S.W. Wen SHORT COMMUNICATION: adverse maternal outcomes in multifetal pregnancies BJOG 111 2004 1294 1296
51. C.C. Wong, K.E. Loewke, N.L. Bossert, B. Behr, C.J. De Jonge, T.M. Baer, and R.A.R. Pera Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage Nat. Biotechnol. 28 2010 1115 1121
52. C. Wong, A. Chen, B. Behr, and S. Shen Time-lapse microscopy and image analysis in basic and clinical embryo development research Reprod. Biomed. Online 26 2013 120 129