Neuroprotective effect of steamed and fermented codonopsis lanceolata

Biomolecules and Therapeutics

Volumn 22, Issue 3, 2014, Pages 246-253

  Weon, Jin Bae ^a   Yun, Bo Ra ^a   Lee, Jiwoo ^a   Eom, Min Rye ^a   Ko, Hyun Jeong ^a   Lee, Hyeon Yong ^b   Park, Dong Sik ^c   Chung, Hee Chul ^d   Chung, Jae Youn ^d   Ma, Choong Je ^a  

^a Kangwon National University   (South Korea)

^b Seowon University   (South Korea)

^c Functional Food and Nutrition Division   (South Korea)

^d Newtree Co Ltd   (South Korea)

Author keywords

Antioxidative activity; Bax; Caspase 3; Codonopsis lanceolata; Neuroprotective activity; Steam and fermentation

Indexed keywords

EID: 84942759057     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2014.019     Document Type: Article

References (50)

1. Albrecht, P., Lewerenz, J., Dittmer, S., Noack, R., Maher, P. and Meth-ner, A. (2010) Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc-as a neuroprotective drug target. CNS Neurol. Disord. Drug Targets 9, 373-382.
2. Antonsson, B. (2004) Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways. Mol. Cell. Biochem. 256, 141-155.
3. Ban, J. Y., Nguyen, H. T., Lee, H. J., Cho, S. O., Ju, H. S., Kim, J. Y., Bae, K., Song, K. S. and Seong, Y. H. (2008) Neuroprotective properties of gallic acid from Sanguisorbae radix on amyloid beta protein (25--35)-induced toxicity in cultured rat cortical neurons. Biol. Pharm. Bull. 31, 149-153.
4. Butterfield, D. A. and Pocernich, C. B. (2003) The glutamatergic system and Alzheimer's disease: therapeutic implications. CNS Drugs 17, 641-652.
5. Byeon, S. E., Choi, W. S., Hong, E. K., Lee, J., Rhee, M. H., Park, H. J. and Cho, J. Y. (2009) Inhibitory effect of saponin fraction from Codonopsis lanceolata on immune cell-mediated inflammatory re-sponses. Arch. Pharm. Res. 32, 813-822.
6. Cho, J. Y., Kim, H. S., Kim, D. H., Yan, J. J., Suh, H. W. and Song, D. K. (2005) Inhibitory effects of long-term administration of ferulic acid on astrocyte activation induced by intracerebroventricular injection of beta-amyloid peptide (1-42) in mice. Prog. Neuropsychopharma-col. Biol. Psychiatry 29, 901-907.
7. Choi, D. W. (1985) Glutamate neurotoxicity in cortical cell cultures is calcium dependent. Neurosci. Lett. 58, 293-297.
8. Choi, D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
9. Conrad, M. and Sato, H. (2012) The oxidative stress-inducible cystine/ glutamate antiporter, system x(c)(-): cystine supplier and beyond. Amino Acids 42, 231-246.
10. Coyle, J. T. and Puttfarcken, P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695.
11. Crapper, D. R. and DeBoni, U. (1978) Brain aging and Alzheimer’s disease. Can. Psychiatr. Assoc. j. 23, 229-233.
12. Deckwerth, T. L., Elliot, J. L., Knudson, C. M., Johnson, Jr. E. M., Snid-er, W. D. and Korsmeyer, S. J. (1996) Bax is required for neuronal death after trophic factor deprivation and during development. Neuron 17, 401-411.
13. Duchen, M. (2000) Mitochondria and calcium: from cell signaling to cell death. J. Physiol. 529, 57-68.
14. Epand, R. F., Martinou, J. C., Montessuit, S., Epand, R. M. and Yip, C.M. (2002) Direct evidence for membrane pore formation by the apoptotic protein Bax. Biochem. Biophys. Res. Commun. 298, 744-749.
15. Fukui, M., Song, J. H., Choi, J., Choi, H. J. and Zhu, B. T. (2009) Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippo-campal cells. Eur. J. Pharmacol. 617, 1-11.
16. Gan, M., Lin, S., Zhang, Y., Zi, J., Song, W., Hu, J., Chen, N., Wang, L., Wang, X. and Shi, J. (2011) Liposoluble constituents from Iodes cirrhosa and their neuroprotective and potassium channel-blocking activity. Zhongguo Zhong Yao Za Zhi 36, 1183-1189.
17. Garthwaite, J. (1991) Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14, 60-67.
18. Ghayur, M. N., Kazim, S. F., Rasheed, H., Khalid, A., Jumani, M. I., Choudhary, M. I. and Gilani, A. H. (2011) Identification of antiplate-let and acetylcholinesterase inhibitory constituents in betel nut. Zhong Xi Yi Jie He Xue Bao 9, 619-625.
19. Gross, A., McDonnell, J. M. and Korsmeyer, J. S. (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13, 1899-1911.
20. He, X., Zou, Y., Yoon, W. B., Park, S. J., Park, D. S. and Ahn, J. (2011) Effects of probiotic fermentation on the enhancement of biological and pharmacological activities of Codonopsis lanceolata extracted by high pressure treatment. J. Biosci. Bioeng. 112, 188-193.
21. Jung, I. H., Jang, S. E., Joh, E. H., Chung, J., Han, M. J. and Kim, D. H. (2012) Lancemaside A isolated from Codonopsis lanceolata and its metabolite echinocystic acid ameliorate scopolamine-induced memory and learning deficits in mice. Phytomedicine 20, 84-88.
22. Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valen-tine, J. S., Ord, T. and Bredesen, D. E. (1993) Bcl-2 inhibition of neuronal death: decreased generation of reactive oxygen species. Science 262, 1274-1277.
23. Knowles, R. G., Palacios, M., Palmer, R. M. J. and Moncada, S. (1989) Formation of nitric oxide from L-arginnie in central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc. Natl. Acad. Sci. U.S.A. 86, 5159-5162.
24. Lafon-Cazal, M., Culcasi, M., Gaven, F., Pietri, S. and Bockaert, J. (1993) Nitric oxide, superoxide and peroxynitrite: putative media-tors of NMDA-induced cell death in cerebellar granule cells. Neuro-pharmacology 32, 1259-1266.
25. Lewerenz, J., Klein, M. and Methner, A. (2006) Cooperative action of glutamate transporters and cystine/glutamate antiporter system X-c(-) protects from oxidative glutamate toxicity. J. Neurochem. 98, 916-925.
26. Li, J. P., Liang, Z. M. and Yuan, Z. (2007) Triterpenoid saponins and anti-inflammatory activity of Codonopsis lanceolata. Pharmazie. 62, 463-466.
27. Liu, J. Li, L. Suo, W. Z. (2009) HT22 hippocampal neuronal cell line possesses functional cholinergic properties. Life Sci. 84, 267-271.
28. Ly, J. D., Grubb, D. R. and Lawen, A. (2003) The mitochondrial membrane potential (ψ) in apoptosis; an update. Apoptosis 8, 115-128.
29. Moncada, S. and Erusalimsky, J. D. (2002) Does nitric oxide modulate mitochondrial energy generation and apoptosis? Nat. Rev. Mol. Cell Biol. 3, 214-220.
30. Murphy, T. H., Miyamoto, M., Sastre, A., Schnaar, R. L. and Coyle, J. T. (1989) Glutamate toxicity in neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2, 1547-1558.
31. 2+ stores. J. Biol. Chem. 277, 9219-9225.
32. Ola, M. S., Nawaz, M. and Ahsan, H. (2011) Role of Bcl-2 family proteins and caspases in the regulation of apoptosis. Mol. Cell. Bio-chem. 351, 41-58.
33. Randall, R. D. and Thayer, S. A. (1992) Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12, 1882-1895.
34. Reynolds, I. J. and Hastings, T. G. (1995) Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15, 3318-3327.
35. Ryu, H. S. (2009) Effect of Codonopsis lanceolatae Extracts on mouse IL-2, IFN-, IL-10 cytokine production by peritoneal macrophage and the ratio of IFN-, IL-10 cytokine. Kor. J. Food Nutr. 22, 69-74.
36. Satoh, T., Enokido, Y., Kubo, T., Yamada, M. and Hatanaka, H. (1998) Oxygen toxicity induces apoptosis in neuronal cells. Cell. Mol. Neu-robiol. 18, 649-666.
37. Suzuki, Y. S., Forman, H. J., Sevanian, A. (1997) Oxidants as stimu-lators of signal transduction. Free Radic. Biol. Med. 22, 269-285.
38. Tan, S., Sagara, Y., Liu, Y., Maher, P. and Schubert, D. (1998a) The regulation of reactive oxygen species production during programmed cell death. J. Cell. Biol. 141, 1423-1432.
39. Tan, S., Wood, M. and Maher, P. (1998b) Oxidative stress induces a form of programmed cell death with characteristics of both apop-tosis and necrosis in neuronal cells. J. Neurochem. 71, 95-105.
40. Tanović, A. and Alfaro, V. (2006) Glutamate-related excitotoxicity ne-u roprotection with memantine, an uncompetitive antagonist of NMDA-glutamate receptor, in Alzheimer's disease and vascular dementia. Rev. Neurol. 42, 607-616.
41. Ushijima, M., Komoto, N., Sugizono, Y., Mizuno, I., Sumihiro, M., Ichi-kawa, M., Hayama, M., Kawahara, N., Nakane, T., Shirota, O., Sekita, S. and Kuroyanagi, M. (2008) Triterpene glycosides from the roots of Codonopsis lanceolata. Chem. Pharm. Bull. 56, 308-314.
42. 2+ loads. J. Neurophysiol. 72, 2563-2569.
43. Weon, J. B., Kim, C. Y., Yang, H. J. and Ma, C. J. (2012) Neuropro-tective compounds isolated from Cynanchum paniculatum. Arch. Pharm. Res. 35, 617-621.
44. Weon, J. B., Yun, B.-R., Lee, J., Eom, M. R., Kim, J. S., Lee, H. Y., Park, D. S., Chung, H. C., Chung, J. Y. and Ma, C. J. (2013) Effect of Codonopsis lanceolata with steamed and fermented process on scopolamine-Induced memory impairment in mice. Biomol. Ther. 21, 405-410.
45. Wyllie, A. H., Kerr, J. F. and Currie, A. R. (1980) Cell death: the signifi-cance of apoptosis. Int. Rev. Cytol. 68, 251-306.
46. Xiang, J., Chao, D. T. and Korsmeyer, S. J. (1996) Bax-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc. Natl. Acad. Sci. U.S.A. 93, 14559-14563.
47. Xu, J., Xilouri, M., Bruban, J., Shioi, J., Shao, Z., Papazoglou, I., Vekrellis, K. and Robakis, N. K. (2011) Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling. Neurobiol. Aging 32, 2326.e5-2326.e16
48. Yang, H. J., Weon, J. B., Lee, B. and Ma, C. J. (2011) The alteration of components in the fermented Hwangryunhaedok-tang and its neuroprotective activity. Pharmacogn. Mag. 7, 207-212.
49. Yongxu, S. and Jicheng, L. (2008) Structural characterization of a wa-ter-soluble polysaccharide from the roots of Codonopsis pilosula and its immunity activity. Int. J. Biol. Macromol. 43, 279-282.
50. Zhang, Y. M. and Bhavnani, B. R. (2005) Glutamate-induced apop-tosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release. BMC Neurosci. 6, 13.