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Volumn 25, Issue , 2015, Pages 177-181

Imaging Neurodegeneration: Steps Toward Brain Network-Based Pathophysiology and Its Potential for Multi-modal Imaging Diagnostics

Author keywords

Alzheimer s disease; Intrinsic brain networks; Multi modal imaging; Neurodegenerative diseases

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PLAQUE; BRAIN ATROPHY; BRAIN FUNCTION; CONNECTOME; DEFAULT MODE NETWORK; HUMAN; MULTIMODAL IMAGING; NERVE DEGENERATION; NEUROIMAGING; NONHUMAN; QUALITATIVE ANALYSIS; REVIEW; BRAIN MAPPING; NERVE CELL NETWORK; NEURODEGENERATIVE DISEASES; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PROCEDURES;

EID: 84942549715     PISSN: 18691439     EISSN: 18691447     Source Type: Journal    
DOI: 10.1007/s00062-015-0438-3     Document Type: Review
Times cited : (6)

References (32)
  • 1
    • 34548014282 scopus 로고    scopus 로고
    • Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging
    • COI: 1:CAS:528:DC%2BD2sXpt1Crt7w%3D, PID: 17704812
    • Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci. 2007;8:700–11.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 700-711
    • Fox, M.D.1    Raichle, M.E.2
  • 2
    • 34247578209 scopus 로고    scopus 로고
    • Intrinsic functional architecture in the anaesthetized monkey brain
    • COI: 1:CAS:528:DC%2BD2sXkvVaju7Y%3D, PID: 17476267
    • Vincent JL, Patel GH, Fox MD, Snyder AZ, Baker JT, Van Essen DC, Zempel JM, Snyder LH, Corbetta M, Raichle ME. Intrinsic functional architecture in the anaesthetized monkey brain. Nature. 2007;447:83–6.
    • (2007) Nature , vol.447 , pp. 83-86
    • Vincent, J.L.1    Patel, G.H.2    Fox, M.D.3    Snyder, A.Z.4    Baker, J.T.5    Van Essen, D.C.6
  • 3
    • 78650574915 scopus 로고    scopus 로고
    • Emergence of resting state networks in the preterm human brain
    • COI: 1:CAS:528:DC%2BC3cXhsVyitLrN, PID: 21041625
    • Doria V, Beckmann CF, Arichi T, Merchant N, Groppo M, Turkheimer FE, Counsell SJ, Murgasova M, Aljabar P, Nunes RG, Larkman DJ, Rees G, Edwards AD. Emergence of resting state networks in the preterm human brain. Proc Natl Acad Sci U S A. 2010;107:20015–20.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20015-20020
    • Doria, V.1    Beckmann, C.F.2    Arichi, T.3    Merchant, N.4    Groppo, M.5    Turkheimer, F.E.6
  • 4
    • 69149106062 scopus 로고    scopus 로고
    • Correspondence of the brain’s functional architecture during activation and rest
    • COI: 1:CAS:528:DC%2BD1MXhtVKru7%2FJ, PID: 19620724
    • Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, Filippini N, Watkins KE, Toro R, Laird AR, Beckmann CF. Correspondence of the brain’s functional architecture during activation and rest. Proc Natl Acad Sci U S A. 2009;106:13040–5.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 13040-13045
    • Smith, S.M.1    Fox, P.T.2    Miller, K.L.3    Glahn, D.C.4    Fox, P.M.5    Mackay, C.E.6
  • 5
    • 80051663721 scopus 로고    scopus 로고
    • Functional network disruption in the degenerative dementias
    • PID: 21778116
    • Pievani M, De Haan W, Wu T, Seeley WW, Frisoni GB. Functional network disruption in the degenerative dementias. Lancet Neurol. 2011;10:829–43.
    • (2011) Lancet Neurol , vol.10 , pp. 829-843
    • Pievani, M.1    De Haan, W.2    Wu, T.3    Seeley, W.W.4    Frisoni, G.B.5
  • 7
    • 1842427969 scopus 로고    scopus 로고
    • Default-mode network activity distinguishes Alzheimer’s disease from healthy aging: evidence from functional MRI
    • COI: 1:CAS:528:DC%2BD2cXjtFKisLg%3D, PID: 15070770
    • Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer’s disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A. 2004;101:4637–42.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4637-4642
    • Greicius, M.D.1    Srivastava, G.2    Reiss, A.L.3    Menon, V.4
  • 8
    • 36749045805 scopus 로고    scopus 로고
    • Selective changes of resting-state networks in individuals at risk for Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD2sXhtl2ltL%2FF, PID: 18003904
    • Sorg C, Riedl V, Mühlau M, Calhoun VD, Eichele T, Läer L, Drzezga A, Förstl H, Kurz A, Zimmer C, Wohlschläger AM. Selective changes of resting-state networks in individuals at risk for Alzheimer’s disease. Proc Natl Acad Sci U S A. 2007;104:18760–5.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18760-18765
    • Sorg, C.1    Riedl, V.2    Muhlau, M.3    Calhoun, V.D.4    Eichele, T.5    Laer, L.6
  • 10
    • 84912108663 scopus 로고    scopus 로고
    • Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects
    • PID: 25266592
    • Lim HK, Nebes R, Snitz B, Cohen A, Mathis C, Price J, Weissfeld L, Klunk W, Aizenstein HJ. Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects. Brain. 2014;137:3327–38.
    • (2014) Brain , vol.137 , pp. 3327-3338
    • Lim, H.K.1    Nebes, R.2    Snitz, B.3    Cohen, A.4    Mathis, C.5    Price, J.6
  • 11
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics
    • COI: 1:CAS:528:DC%2BD38Xls1Cju7s%3D, PID: 12130773
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science. 2002;297:353–6.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 12
    • 77951921512 scopus 로고    scopus 로고
    • Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer’s disease
    • PID: 20410145
    • Zhou J, Greicius MD, Gennatas ED, Growdon ME, Jang JY, Rabinovici GD, Kramer JH, Weiner M, Miller BL, Seeley WW. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer’s disease. Brain. 2010;133:1352–67.
    • (2010) Brain , vol.133 , pp. 1352-1367
    • Zhou, J.1    Greicius, M.D.2    Gennatas, E.D.3    Growdon, M.E.4    Jang, J.Y.5    Rabinovici, G.D.6
  • 13
    • 84887230568 scopus 로고    scopus 로고
    • Reduced functional connectivity in early-stage drug-naive Parkinson’s disease: a resting-state fMRI study
    • PID: 24074808
    • Luo C, Song W, Chen Q, Zheng Z, Chen K, Cao B, Yang J, Li J, Huang X, Gong Q, Shang HF. Reduced functional connectivity in early-stage drug-naive Parkinson’s disease: a resting-state fMRI study. Neurobiol Aging. 2014;35:431–41.
    • (2014) Neurobiol Aging , vol.35 , pp. 431-441
    • Luo, C.1    Song, W.2    Chen, Q.3    Zheng, Z.4    Chen, K.5    Cao, B.6
  • 14
    • 64149093013 scopus 로고    scopus 로고
    • Neurodegenerative diseases target large-scale human brain networks
    • COI: 1:CAS:528:DC%2BD1MXmvVaitbg%3D, PID: 19376066
    • Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD. Neurodegenerative diseases target large-scale human brain networks. Neuron. 2009;62:42–52.
    • (2009) Neuron , vol.62 , pp. 42-52
    • Seeley, W.W.1    Crawford, R.K.2    Zhou, J.3    Miller, B.L.4    Greicius, M.D.5
  • 15
    • 84863337784 scopus 로고    scopus 로고
    • Predicting regional neurodegeneration from the healthy brain functional connectome
    • COI: 1:CAS:528:DC%2BC38XktlKqsro%3D, PID: 22445348
    • Zhou J, Gennatas ED, Kramer JH, Miller BL, Seeley WW. Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron. 2012;73:1216–27.
    • (2012) Neuron , vol.73 , pp. 1216-1227
    • Zhou, J.1    Gennatas, E.D.2    Kramer, J.H.3    Miller, B.L.4    Seeley, W.W.5
  • 16
    • 67650875899 scopus 로고    scopus 로고
    • Amyloid deposition is associated with impaired default network function in older persons without dementia
    • COI: 1:CAS:528:DC%2BD1MXhsVCiurjM, PID: 19640477
    • Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron. 2009;63:178–88.
    • (2009) Neuron , vol.63 , pp. 178-188
    • Sperling, R.A.1    Laviolette, P.S.2    O’keefe, K.3    O’brien, J.4    Rentz, D.M.5    Pihlajamaki, M.6
  • 17
    • 79957800704 scopus 로고    scopus 로고
    • Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden
    • PID: 21490054
    • Drzezga A, Becker JA, Van Dijk KR, Sreenivasan A, Talukdar T, Sullivan C, Schultz AP, Sepulcre J, Putcha D, Greve D, Johnson KA, Sperling RA. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain. 2011;134:1635–46.
    • (2011) Brain , vol.134 , pp. 1635-1646
    • Drzezga, A.1    Becker, J.A.2    Van Dijk, K.R.3    Sreenivasan, A.4    Talukdar, T.5    Sullivan, C.6
  • 18
    • 84903539695 scopus 로고    scopus 로고
    • Within-patient correspondence of amyloid-beta and intrinsic network connectivity in Alzheimer’s disease
    • PID: 24771519
    • Myers N, Pasquini L, Göttler J, Grimmer T, Koch K, Ortner M, Neitzel J, Mühlau M, Förster S, Kurz A, Förstl H, Zimmer C, Wohlschläger AM, Riedl V, Drzezga A, Sorg C. Within-patient correspondence of amyloid-beta and intrinsic network connectivity in Alzheimer’s disease. Brain. 2014;137:2052–64.
    • (2014) Brain , vol.137 , pp. 2052-2064
    • Myers, N.1    Pasquini, L.2    Gottler, J.3    Grimmer, T.4    Koch, K.5    Ortner, M.6
  • 19
    • 84912103003 scopus 로고    scopus 로고
    • Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders
    • PID: 25412207
    • Iturria-Medina Y, Sotero RC, Toussaint PJ, Evans AC. Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders. PLoS Comput Biol. 2014;10:e1003956.
    • (2014) PLoS Comput Biol , vol.10
    • Iturria-Medina, Y.1    Sotero, R.C.2    Toussaint, P.J.3    Evans, A.C.4
  • 20
    • 84858648349 scopus 로고    scopus 로고
    • A network diffusion model of disease progression in dementia
    • COI: 1:CAS:528:DC%2BC38XktlKqt78%3D, PID: 22445347
    • Raj A, Kuceyeski A, Weiner M. A network diffusion model of disease progression in dementia. Neuron. 2012;73:1204–15.
    • (2012) Neuron , vol.73 , pp. 1204-1215
    • Raj, A.1    Kuceyeski, A.2    Weiner, M.3
  • 21
    • 84921417870 scopus 로고    scopus 로고
    • for the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Network diffusion model of progression predicts longitudinal patterns of atrophy and metabolism in Alzheimer’s disease
    • Raj A, Locastro E, Kuceyeski A, Tosun D, Relkin N, Weiner M; for the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Network diffusion model of progression predicts longitudinal patterns of atrophy and metabolism in Alzheimer’s disease. Cell Rep. 2015; 10:359–69.
    • (2015) Cell Rep , vol.10 , pp. 359-369
    • Raj, A.1    Locastro, E.2    Kuceyeski, A.3    Tosun, D.4    Relkin, N.5    Weiner, M.6
  • 22
    • 84877149884 scopus 로고    scopus 로고
    • Resting brains never rest: computational insights into potential cognitive architectures
    • COI: 1:CAS:528:DC%2BC3sXlt1egsLw%3D, PID: 23561718
    • Deco G, Jirsa VK, Mcintosh AR. Resting brains never rest: computational insights into potential cognitive architectures. Trends Neurosci. 2013;36:268–74.
    • (2013) Trends Neurosci , vol.36 , pp. 268-274
    • Deco, G.1    Jirsa, V.K.2    Mcintosh, A.R.3
  • 23
    • 34547219105 scopus 로고    scopus 로고
    • Network structure of cerebral cortex shapes functional connectivity on multiple time scales
    • COI: 1:CAS:528:DC%2BD2sXmvVCms7s%3D, PID: 17548818
    • Honey CJ, Kotter R, Breakspear M, Sporns O. Network structure of cerebral cortex shapes functional connectivity on multiple time scales. Proc Natl Acad Sci U S A. 2007;104:10240–5.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10240-10245
    • Honey, C.J.1    Kotter, R.2    Breakspear, M.3    Sporns, O.4
  • 24
    • 84878873908 scopus 로고    scopus 로고
    • Selectively and progressively disrupted structural connectivity of functional brain networks in Alzheimer’s disease—revealed by a novel framework to analyze edge distributions of networks detecting disruptions with strong statistical evidence
    • PID: 23668966
    • Hahn K, Myers N, Prigarin S, Rodenacker K, Kurz A, Förstl H, Zimmer C, Wohlschläger AM, Sorg C. Selectively and progressively disrupted structural connectivity of functional brain networks in Alzheimer’s disease—revealed by a novel framework to analyze edge distributions of networks detecting disruptions with strong statistical evidence. Neuroimage. 2013;81:96–109.
    • (2013) Neuroimage , vol.81 , pp. 96-109
    • Hahn, K.1    Myers, N.2    Prigarin, S.3    Rodenacker, K.4    Kurz, A.5    Forstl, H.6
  • 25
    • 60849136325 scopus 로고    scopus 로고
    • Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD1MXit1Wiur0%3D, PID: 19211893
    • Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer’s disease. J Neurosci. 2009;29:1860–73.
    • (2009) J Neurosci , vol.29 , pp. 1860-1873
    • Buckner, R.L.1    Sepulcre, J.2    Talukdar, T.3    Krienen, F.M.4    Liu, H.5    Hedden, T.6
  • 26
    • 71549168043 scopus 로고    scopus 로고
    • White matter damage in frontotemporal dementia and Alzheimer’s disease measured by diffusion MRI
    • PID: 19439421
    • Zhang Y, Schuff N, Du AT, Rosen HJ, Kramer JH, Gorno-Tempini ML, Miller BL, Weiner MW. White matter damage in frontotemporal dementia and Alzheimer’s disease measured by diffusion MRI. Brain. 2009;132:2579–92.
    • (2009) Brain , vol.132 , pp. 2579-2592
    • Zhang, Y.1    Schuff, N.2    Du, A.T.3    Rosen, H.J.4    Kramer, J.H.5    Gorno-Tempini, M.L.6
  • 27
    • 84866757398 scopus 로고    scopus 로고
    • Prediction of Alzheimer’s disease using individual structural connectivity networks
    • PID: 22405045
    • Shao J, Myers N, Yang Q, Feng J, Plant C, Böhm C, Förstl H, Kurz A, Zimmer C, Meng C, Riedl V, Wohlschläger A, Sorg C. Prediction of Alzheimer’s disease using individual structural connectivity networks. Neurobiol Aging. 2012;33:2756–65.
    • (2012) Neurobiol Aging , vol.33 , pp. 2756-2765
    • Shao, J.1    Myers, N.2    Yang, Q.3    Feng, J.4    Plant, C.5    Bohm, C.6
  • 28
    • 84855453290 scopus 로고    scopus 로고
    • Identification of MCI individuals using structural and functional connectivity networks
    • PID: 22019883
    • Wee CY, Yap PT, Zhang D, Denny K, Browndyke JN, Potter GG, Welsh-Bohmer KA, Wang L, Shen D. Identification of MCI individuals using structural and functional connectivity networks. Neuroimage. 2012;59:2045–56.
    • (2012) Neuroimage , vol.59 , pp. 2045-2056
    • Wee, C.Y.1    Yap, P.T.2    Zhang, D.3    Denny, K.4    Browndyke, J.N.5    Potter, G.G.6
  • 29
    • 84928769522 scopus 로고    scopus 로고
    • Multimodal analysis of functional and structural disconnection in Alzheimer’s disease using multiple kernel SVM
    • Dyrba M, Grothe M, Kirste T, Teipel SJ. Multimodal analysis of functional and structural disconnection in Alzheimer’s disease using multiple kernel SVM. Hum Brain Mapp. 2015;6:2118–31.
    • (2015) Hum Brain Mapp , vol.6 , pp. 2118-2131
    • Dyrba, M.1    Grothe, M.2    Kirste, T.3    Teipel, S.J.4
  • 30
    • 78650991678 scopus 로고    scopus 로고
    • Clinical applications of resting state functional connectivity
    • PID: 20592951
    • Fox MD, Greicius M. Clinical applications of resting state functional connectivity. Front Syst Neurosci. 2010;4:19.
    • (2010) Front Syst Neurosci , vol.4 , pp. 19
    • Fox, M.D.1    Greicius, M.2
  • 31
    • 77649218601 scopus 로고    scopus 로고
    • Toward discovery science of human brain function
    • COI: 1:CAS:528:DC%2BC3cXjs1elsrk%3D, PID: 20176931
    • Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kötter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP. Toward discovery science of human brain function. Proc Natl Acad Sci U S A. 2010;107:4734–9.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 4734-4739
    • Biswal, B.B.1    Mennes, M.2    Zuo, X.N.3    Gohel, S.4    Kelly, C.5    Smith, S.M.6
  • 32
    • 84880325951 scopus 로고    scopus 로고
    • Resting-state fMRI in the human connectome project
    • PID: 23702415
    • Smith SM, Beckmann CF, Andersson J, Auerbach EJ, Bijsterbosch J, Douaud G, Duff E, Feinberg DA, Griffanti L, Harms MP, Kelly M, Laumann T, Miller KL, Moeller S, Petersen S, Power J, Salimi-Khorshidi G, Snyder AZ, Vu AT, Woolrich MW, Xu J, Yacoub E, Uğurbil K, Van Essen DC, Glasser MF; WU-Minn HCP Consortium. Resting-state fMRI in the human connectome project. Neuroimage. 2013;80:144–68.
    • (2013) Neuroimage , vol.80 , pp. 144-168
    • Smith, S.M.1    Beckmann, C.F.2    Andersson, J.3    Auerbach, E.J.4    Bijsterbosch, J.5    Douaud, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.