Polymorphisms of pesticide-metabolizing genes in children living in intensive farming communities

Chemosphere

Volumn 139, Issue , 2015, Pages 534-540

  Gómez Martín, Antonio ^a   Hernández, Antonio F ^a   Martínez González, Luis Javier ^a   González Alzaga, Beatriz ^a,b   Rodríguez Barranco, Miguel ^a,b   López Flores, Inmaculada ^a   Aguilar Garduno, Clemente ^c   Lacasana, Marina ^a,b,d  

^a UNIVERSITY OF GRANADA   (Spain)

^b ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^c Center for Research in Public Health (CSISP)   (Spain)

^d CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

Author keywords

CNVs; Environmental toxicants; Esterases; Genetic biomarkers; Organophosphates; SNPs; Xenobiotic metabolizing enzymes

Indexed keywords

DETOXIFICATION; ENZYMES; PESTICIDES; PLANTS (BOTANY); POLYMERASE CHAIN REACTION;

CNVS; ENVIRONMENTAL TOXICANTS; ESTERASES; ORGANOPHOSPHATES; SNPS; XENOBIOTIC-METABOLIZING ENZYMES;

GENES;

ARYLDIALKYLPHOSPHATASE 1; CHOLINESTERASE; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; GENOMIC DNA; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; ORGANOPHOSPHATE PESTICIDE; UNCLASSIFIED DRUG; UNCLASSIFIED ENZYME; XENOBIOTIC METABOLIZING ENZYME; ARYLDIALKYLPHOSPHATASE; CYP3A PROTEIN, HUMAN; CYTOCHROME P450 3A; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE S-TRANSFERASE T1; GLUTATHIONE TRANSFERASE; PESTICIDE; POLLUTANT; PON1 PROTEIN, HUMAN;

ALLELE; ANNUAL VARIATION; BIOMARKER; CHILD HEALTH; CYTOCHROME; DETOXIFICATION; DNA; ENVIRONMENTAL RISK; ENZYME ACTIVITY; GENE EXPRESSION; GENOTYPE; INTENSIVE AGRICULTURE; METABOLISM; MOLECULAR ANALYSIS; ORGANOPHOSPHORUS PESTICIDE; PESTICIDE; POLLUTION EFFECT; POLLUTION EXPOSURE; POLYMORPHISM; XENOBIOTICS;

AGRICULTURE; ARTICLE; CHILD; CONTROLLED STUDY; COPY NUMBER VARIATION; DETOXIFICATION; ENVIRONMENTAL EXPOSURE; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC DIFFERENCE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; HYDROLYSIS; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; PROMOTER REGION; PROTEIN EXPRESSION; ADOLESCENT; ADVERSE EFFECTS; ANALYSIS; DRUG EFFECTS; DRUG INACTIVATION; GENETICS; MALE; PHARMACOKINETICS; POLLUTANT; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN; TOXICITY;

SPAIN;

ADOLESCENT; AGRICULTURE; ARYLDIALKYLPHOSPHATASE; CHILD; CYTOCHROME P-450 CYP3A; DNA COPY NUMBER VARIATIONS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; GENE FREQUENCY; GLUTATHIONE TRANSFERASE; HAPLOTYPES; HUMANS; INACTIVATION, METABOLIC; LINKAGE DISEQUILIBRIUM; MALE; PESTICIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; SPAIN;

EID: 84942540733     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2015.07.079     Document Type: Article

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