A novel mouse model of thromboembolic stroke

Journal of Neuroscience Methods

Volumn 256, Issue , 2015, Pages 203-211

  Chen, Yingxin ^a   Zhu, Wenbin ^a   Zhang, Wenri ^a   Libal, Nicole ^a   Murphy, Stephanie J ^a   Offner, Halina ^a,b   Alkayed, Nabil J ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Cerebral ischemia; Mouse; Optical microangiography; Stroke; Thromboembolic; tPA

Indexed keywords

ALTEPLASE; THROMBIN; FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN INFARCTION SIZE; CEREBROVASCULAR ACCIDENT; CONTINUOUS INFUSION; CONTROLLED STUDY; CORPUS STRIATUM; HEMISPHERE; INTERNAL CAROTID ARTERY; LASER DOPPLER FLOWMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; MOUSE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; OPERATION DURATION; PRIORITY JOURNAL; REPRODUCIBILITY; ANIMAL; BRAIN CIRCULATION; BRAIN ISCHEMIA; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; HIPPOCAMPUS; INTRACRANIAL EMBOLISM; INTRACRANIAL THROMBOSIS; NEUROSURGERY; PATHOLOGY; PROCEDURES; RANDOMIZATION; STROKE; TRANSGENIC MOUSE; VALIDATION STUDY;

ANIMALS; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; FIBRINOLYTIC AGENTS; HIPPOCAMPUS; INTRACRANIAL EMBOLISM; INTRACRANIAL THROMBOSIS; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROSURGICAL PROCEDURES; RANDOM ALLOCATION; STROKE; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84942525869     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2015.09.013     Document Type: Review

References (40)

1. Ansar S., Chatzikonstantinou E., Wistuba-Schier A., Mirau-Weber S., Fatar M., Hennerici M.G., et al. Characterization of a new model of thromboembolic stroke in C57 black/6J mice. Transl Stroke Res 2014, 5(4):526-533.
2. Bagot C.N., Arya R. Virchow and his triad: a question of attribution. Br J Haematol 2008, 143(2):180-190.
3. Barber P.A., Hoyte L., Colbourne F., Buchan A.M. Temperature-regulated model of focal ischemia in the mouse: a study with histopathological and behavioral outcomes. Stroke 2004, 35(7):1720-1725.
4. Belayev L., Alonso O.F., Busto R., Zhao W., Ginsberg M.D. Middle cerebral artery occlusion in the rat by intraluminal suture: neurological and pathological evaluation of an improved model. Stroke 1996, 27(9):1616-1623.
5. Busch E., Kruger K., Hossmann K.A. Improved model of thromboembolic stroke and rt-PA induced reperfusion in the rat. Brain Res 1997, 778(1):16-24.
6. Cai H., Yao H., Ibayashi S., Uchimura H., Fujishima M. Photothrombotic middle cerebral artery occlusion in spontaneously hypertensive rats: influence of substrain, gender, and distal middle cerebral artery patterns on infarct size. Stroke 1998, 29(9):1982-1987.
7. Casals Juliana B., Pieri Naira C.G., Feitosa Matheus L.T., Ercolin Anna C.M., Roballo Kelly C.S., Barreto Rodrigo S.N., et al. The use of animal models for stroke research: a review. Comp Med 2011, 61(4):305-313. [August].
8. Chen Y., Bodhankar S., Murphy S.J., Vandenbark A.A., Alkayed N.J., Offner H. Intrastriatal B-cell administration limits infarct size after stroke in B-cell deficient mice. Metab Brain Dis 2012, 27(4):487-493.
9. del Zoppo G.J., Poeck K., Pessin M.S., Wolpert S.M., Furlan A.J., et al. Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann Neurol 1992, 32(1):78-86.
10. Gillum R.F. New considerations in analyzing stroke and heart disease mortality trends: the year 2000 age standard and the international statistical classification of diseases and related health problems, 10th revision. Stroke: J Cereb Circ 2002, 33(6):1717-1721.
11. Go A.S., Mozaffarian D., Roger V.L., Benjamin E.J., Berry J.D., Borden W.B., et al. Heart disease and stroke statistics-2013 update: a report from the American Heart Association. Circulation 2013, 127:e6-e245. [Published corrections appear in Circulation. 2013; 127: e841 and Circulation. 2013;127:doi: 10.1161/CIR.0b013e31828124ad].
12. Hacke W., Kaste M., Bluhmki E., Brozman M., Dávalos A., Guidetti D., et al. ECASS investigators. Thrombolysis with alteplase 3-4.5h after acute ischemic stroke. New Engl J Med 2008, 359(13):1317-1329.
13. Hata R., Maeda K., Hermann D., Mies G., Hossmann K.-A. Evolution of brain infarction after transient focal ischemia in mice. J Cereb Blood Flow Metab 2000, 20(6):937-946.
14. Hossmann K.A. Experimental models for the investigation of brain ischemia. Cardiovasc Res 1998, 39(1):106-120.
15. Hossmann K.A. The two pathophysiologies of focal brain ischemia: implications for translational stroke research. J Cereb Blood Flow Metab 2012, 32(7):1310-1316.
16. Kitagawa K., Matsumoto M., Yang G., Mabuchi T., Yagita Y., Hori M., et al. Cerebral ischemia after bilateral carotid artery occlusion and intraluminal suture occlusion in mice: evaluation of the patency of the posterior communicating artery. J Cereb Blood Flow Metab 1998, 18(5):570-579.
17. Labat-gest V., Tomasi S. Photothrombotic ischemia: a minimally invasive and reproducible photochemical cortical lesion model for mouse stroke studies. J Vis Exp 2013, 9(76):e50370.
18. Lee J.K., Park M.S., Kim Y.S., Moon K.S., Joo S.P., Kim T.S., et al. Photochemically induced cerebral ischemia in a mouse model. Surg Neurol 2007, 67(6):620-625.
19. Liu S., Zhen G., Meloni B.P., Campbell K., Winn H.R. Rodent stroke model guidelines for preclinical stroke trials (1st edition). J Exp Stroke Transl Med 2009, 2(2):2-27.
20. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20(1):84-91.
21. Orset C., Macrez R., Young A.R., Panthou D., Angles-Cano E., Maubert E., et al. Mouse model of in situ thromboembolic stroke and reperfusion. Stroke 2007, 38(10):2771-2778.
22. Overgaard K., Sereghy T., Boysen G., Pedersen H., Høyer S., Diemer N.H. A rat model of reproducible cerebral infarction using thrombotic blood clot emboli. J Cereb Blood Flow Metab 1992, 12(3):484-490.
23. Reglodi D., Somogyvari-Vigh A., Maderdrut J.L., Vigh S., Arimura A. Postischemic spontaneous hyperthermia and its effects in middle cerebral artery occlusion in the rat. Exp Neurol 2000, 163:399-407.
24. Ren M., Lin Z.J., Qian H., Choudhury G.R., Liu R., Liu H., et al. Embolic middle cerebral artery occlusion model using thrombin and fibrinogen composed clots in rat. J Neurosci Methods 2012, 211(2):296-304.
25. Saver J.L. Improving reperfusion therapy for acute ischaemic stroke. J Thromb Haemost 2011, 9(Suppl 1):333-343.
26. Schunke K.J., Toung T.K., Zhang J., Pathak A.P., Xu J., Zhang J., et al. A novel atherothrombotic model of ischemic stroke induced by injection of collagen into the cerebral vasculature. J Neurosci Methods 2015, 239:65-74.
27. Siller-Matula J.M., Schwameis M., Blann A., Mannhalter C., Jilma B. Thrombin as a multi-functional enzyme. Focus on in vitro and in vivo effects. Thromb Haemost 2011, 106(6):1020-1033.
28. Subramanian S., Zhang B., Kosaka Y., Burrows G.G., Grafe M.R., Vandenbark A.A., et al. T cell receptor ligand treats experimental stroke. Stroke 2009, 40(7):2539-2545.
29. Towfighi A., Saver J.L. Stroke declines from third to fourth leading cause of death in the United States. Stroke 2011, 42(8):2351-2355.
30. Wahlgren N., Ahmed N., Dávalos A., Hacke W., Millán M., Muir K., et al. Thrombolysis with alteplase 3-4.5h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet 2008, 372(11):1303-1309.
31. Watson B.D., Prado R., Veloso A., Brunschwig J.-P., Dietrich W.D. Cerebral blood flow restoration and reperfusion injury after ultraviolet laser-facilitated middle cerebral artery recanalization in rat thrombotic stroke. Stroke 2002, 33(2):428-434.
32. Wu L., Xu L., Xu X., Fan X., Xie Y., Yang L., et al. Keep warm and get success: the role of postischemic temperature in the mouse middle cerebral artery occlusion model. Brain Res Bull 2014, 101:12-17.
33. Yao H., Ibayashi S., Sugimori H., Fujii K., Fujishima M. Simplified model of krypton laser-induced thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats. Stroke 1996, 27(2):333-336.
34. Yao H., Sugimori H., Fukuda K., Takada J., Ooboshi H., Kitazono T., et al. Photothrombotic middle cerebral artery occlusion and reperfusion laser system in spontaneously hypertensive rats. Stroke 2003, 34(11):2716-2721.
35. Zhang R.L., Chopp M., Zhang Z.G., Jiang Q., Ewing J.R. A rat model of focal embolic cerebral ischemia. Brain Res 1997, 766(1-2):83-92.
36. Zhang Z., Chopp M., Zhang R.L., Goussev A. A mouse model of embolic focal cerebral ischemia. J Cereb Blood Flow Metab 1997, 17(10):1081-1088.
37. Zhang Z., Zhang R.L., Jiang Q., Raman S.B., Cantwell L., Chopp M. A new rat model of thrombotic focal cerebral ischemia. J Cereb Blood Flow Metab 1997, 17(2):123-135.
38. Zhang Z.G., Zhang L., Ding G., Jiang Q., Zhang R.L., Zhang X., et al. A model of mini-embolic stroke offers measurements of the neurovascular unit response in the living mouse. Stroke 2005, 36(12):2701-2704.
39. Zhang F., Guo R.M., Yang M., Wen X.H., Shen J. A stable focal cerebral ischemia injury model in adult mice: assessment using 7T MR imaging. AJNR Am J Neuroradiol 2012, 33(5):935-939.
40. Zhu W., Libal N.L., Casper A., Bodhankar S., Offner H., Alkayed N.J. Recombinant T cell receptor ligand treatment improves neurological outcome in the presence of tissue plasminogen activator in experimental ischemic stroke. Transl Stroke Res 2014, 5(5):612-617.