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Volumn 8, Issue 5, 2015, Pages 455-463

Hepatitis B virus X protein stabilizes cyclin D1 and increases cyclin D1 nuclear accumulation through ERK-mediated inactivation of GSK-3β

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; HEPATITIS B VIRUS X PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; CCND1 PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; TRANSACTIVATOR PROTEIN;

EID: 84942513073     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-14-0384     Document Type: Article
Times cited : (20)

References (33)
  • 1
    • 79956271546 scopus 로고    scopus 로고
    • Viral hepatitis B and hepatocellular carcinoma
    • Michielsen P, Ho E. Viral hepatitis B and hepatocellular carcinoma. Acta Gastroenterol Belg 2011;74:4-8.
    • (2011) Acta Gastroenterol Belg , vol.74 , pp. 4-8
    • Michielsen, P.1    Ho, E.2
  • 2
    • 0030133133 scopus 로고    scopus 로고
    • Hepatitis B virus transcriptional activators: Mechanisms and possible role in oncogenesis
    • Henkler FF, Koshy R. Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis. J Viral Hepat 1996;3:109-21.
    • (1996) J Viral Hepat , vol.3 , pp. 109-121
    • Henkler, F.F.1    Koshy, R.2
  • 3
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • Tang H, Oishi N, Kaneko S, Murakami S. Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci 2006;97:977-83.
    • (2006) Cancer Sci , vol.97 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 4
    • 84893414836 scopus 로고    scopus 로고
    • Hepatitis B virus-induced hepatocellular carcinoma: The role of the virus x protein
    • Motavaf M, Safari S, Saffari JM, Alavian SM. Hepatitis B virus-induced hepatocellular carcinoma: the role of the virus x protein. Acta Virol 2013;57:389-96.
    • (2013) Acta Virol , vol.57 , pp. 389-396
    • Motavaf, M.1    Safari, S.2    Saffari, J.M.3    Alavian, S.M.4
  • 5
    • 0013439945 scopus 로고    scopus 로고
    • Cycling to cancer with cyclin D1
    • Diehl JA. Cycling to cancer with cyclin D1. Cancer Biol Ther 2002;1:226-31.
    • (2002) Cancer Biol Ther , vol.1 , pp. 226-231
    • Diehl, J.A.1
  • 6
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
    • Kato J, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev 1993;7:331-42.
    • (1993) Genes Dev , vol.7 , pp. 331-342
    • Kato, J.1    Matsushime, H.2    Hiebert, S.W.3    Ewen, M.E.4    Sherr, C.J.5
  • 7
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
    • Diehl JA, Cheng M, Roussel MF, Sherr CJ. Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998;12:3499-511.
    • (1998) Genes Dev , vol.12 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 8
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • Alt JR, Cleveland JL, Hannink M, Diehl JA. Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev 2000;14:3102-14.
    • (2000) Genes Dev , vol.14 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 9
    • 33750460897 scopus 로고    scopus 로고
    • Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4- alphaB crystallin) complex
    • Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, et al. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4- alphaB crystallin) complex. Mol Cell 2006;24:355-66.
    • (2006) Mol Cell , vol.24 , pp. 355-366
    • Lin, D.I.1    Barbash, O.2    Kumar, K.G.3    Weber, J.D.4    Harper, J.W.5    Klein-Szanto, A.J.6
  • 11
    • 34648824397 scopus 로고    scopus 로고
    • Genetic and molecular pathogenesis of mantle cell lymphoma: Perspectives for new targeted therapeutics
    • Jares P, Colomer D, Campo E. Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer 2007;7:750-62.
    • (2007) Nat Rev Cancer , vol.7 , pp. 750-762
    • Jares, P.1    Colomer, D.2    Campo, E.3
  • 12
    • 0034885998 scopus 로고    scopus 로고
    • Cyclin D1 expression and retinoblastoma gene protein (pRB) expression in esophageal squamous cell carcinoma
    • Ikeguchi M, Sakatani T, Ueta T, Kaibara N. Cyclin D1 expression and retinoblastoma gene protein (pRB) expression in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol 2001;127:531-6.
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 531-536
    • Ikeguchi, M.1    Sakatani, T.2    Ueta, T.3    Kaibara, N.4
  • 13
    • 0034780882 scopus 로고    scopus 로고
    • Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II
    • Jin M, Inoue S, Umemura T, Moriya J, Arakawa M, Nagashima K, et al. Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II. Lung Cancer 2001;34:207-18.
    • (2001) Lung Cancer , vol.34 , pp. 207-218
    • Jin, M.1    Inoue, S.2    Umemura, T.3    Moriya, J.4    Arakawa, M.5    Nagashima, K.6
  • 14
    • 0035038252 scopus 로고    scopus 로고
    • Cyclin D1 overexpression in hepatocellular carcinoma
    • Joo M, Kang YK, Kim MR, Lee HK, Jang JJ. Cyclin D1 overexpression in hepatocellular carcinoma. Liver 2001;21:89-95.
    • (2001) Liver , vol.21 , pp. 89-95
    • Joo, M.1    Kang, Y.K.2    Kim, M.R.3    Lee, H.K.4    Jang, J.J.5
  • 16
    • 39749200927 scopus 로고    scopus 로고
    • Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis
    • Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA. Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis. Oncogene 2008;27:1231-42.
    • (2008) Oncogene , vol.27 , pp. 1231-1242
    • Lin, D.I.1    Lessie, M.D.2    Gladden, A.B.3    Bassing, C.H.4    Wagner, K.U.5    Diehl, J.A.6
  • 17
    • 33845995100 scopus 로고    scopus 로고
    • Upregulation of cyclin D1 by HBx is mediated by NF-kappaB2/BCL3 complex through kappaB site of cyclin D1 promoter
    • Park SG, Chung C, Kang H, Kim JY, Jung G. Upregulation of cyclin D1 by HBx is mediated by NF-kappaB2/BCL3 complex through kappaB site of cyclin D1 promoter. J Biol Chem 2006;281:31770-7.
    • (2006) J Biol Chem , vol.281 , pp. 31770-31777
    • Park, S.G.1    Chung, C.2    Kang, H.3    Kim, J.Y.4    Jung, G.5
  • 18
    • 22544433759 scopus 로고    scopus 로고
    • Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of betacatenin
    • Ding Q, Xia W, Liu JC, Yang JY, Lee DF, Xia J, et al. Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of betacatenin. Mol Cell 2005;19:159-70.
    • (2005) Mol Cell , vol.19 , pp. 159-170
    • Ding, Q.1    Xia, W.2    Liu, J.C.3    Yang, J.Y.4    Lee, D.F.5    Xia, J.6
  • 19
    • 84859105915 scopus 로고    scopus 로고
    • Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylation
    • Khattar E, Mukherji A, Kumar V. Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylation. FEBS J 2012;279:1220-30.
    • (2012) FEBS J , vol.279 , pp. 1220-1230
    • Khattar, E.1    Mukherji, A.2    Kumar, V.3
  • 20
    • 0030916209 scopus 로고    scopus 로고
    • Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
    • Diehl JA, Zindy F, Sherr CJ. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev 1997;11:957-72.
    • (1997) Genes Dev , vol.11 , pp. 957-972
    • Diehl, J.A.1    Zindy, F.2    Sherr, C.J.3
  • 21
    • 0242526150 scopus 로고    scopus 로고
    • An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene
    • Lu F, Gladden AB, Diehl JA. An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. Cancer Res 2003;63:7056-61.
    • (2003) Cancer Res , vol.63 , pp. 7056-7061
    • Lu, F.1    Gladden, A.B.2    Diehl, J.A.3
  • 22
    • 84857981395 scopus 로고    scopus 로고
    • Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinoma
    • Xie Q, Chen X, Lu F, Zhang T, Hao M, Wang Y, et al. Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinoma. Cancer 2012;118:2431-42.
    • (2012) Cancer , vol.118 , pp. 2431-2442
    • Xie, Q.1    Chen, X.2    Lu, F.3    Zhang, T.4    Hao, M.5    Wang, Y.6
  • 23
    • 33244481730 scopus 로고    scopus 로고
    • Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma
    • Gladden AB, Woolery R, Aggarwal P, Wasik MA, Diehl JA. Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma. Oncogene 2006;25:998-1007.
    • (2006) Oncogene , vol.25 , pp. 998-1007
    • Gladden, A.B.1    Woolery, R.2    Aggarwal, P.3    Wasik, M.A.4    Diehl, J.A.5
  • 24
    • 11244264657 scopus 로고    scopus 로고
    • C-terminal sequences direct cyclin D1-CRM1 binding
    • Benzeno S, Diehl JA. C-terminal sequences direct cyclin D1-CRM1 binding. J Biol Chem 2004;279:56061-6.
    • (2004) J Biol Chem , vol.279 , pp. 56061-56066
    • Benzeno, S.1    Diehl, J.A.2
  • 26
    • 33749863640 scopus 로고    scopus 로고
    • Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1
    • Benzeno S, Lu F, Guo M, Barbash O, Zhang F, Herman JG, et al. Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1. Oncogene 2006;25:6291-303.
    • (2006) Oncogene , vol.25 , pp. 6291-6303
    • Benzeno, S.1    Lu, F.2    Guo, M.3    Barbash, O.4    Zhang, F.5    Herman, J.G.6
  • 27
    • 45849131324 scopus 로고    scopus 로고
    • Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer
    • Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, et al. Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell 2008;14:68-78.
    • (2008) Cancer Cell , vol.14 , pp. 68-78
    • Barbash, O.1    Zamfirova, P.2    Lin, D.I.3    Chen, X.4    Yang, K.5    Nakagawa, H.6
  • 28
    • 0034640541 scopus 로고    scopus 로고
    • Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation
    • Rimerman RA, Gellert-Randleman A, Diehl JA. Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation. J Biol Chem 2000;275:14736-42.
    • (2000) J Biol Chem , vol.275 , pp. 14736-14742
    • Rimerman, R.A.1    Gellert-Randleman, A.2    Diehl, J.A.3
  • 30
    • 54549120290 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 and cancer: Good cop, bad Cop?
    • Patel S, Woodgett J. Glycogen synthase kinase-3 and cancer: good cop, bad cop? Cancer Cell 2008;14:351-3.
    • (2008) Cancer Cell , vol.14 , pp. 351-353
    • Patel, S.1    Woodgett, J.2
  • 31
    • 33750867472 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3-an overview of an over-achieving protein kinase
    • Kockeritz L, Doble B, Patel S, Woodgett JR. Glycogen synthase kinase-3-an overview of an over-achieving protein kinase. Curr Drug Targets 2006;7:1377-88.
    • (2006) Curr Drug Targets , vol.7 , pp. 1377-1388
    • Kockeritz, L.1    Doble, B.2    Patel, S.3    Woodgett, J.R.4
  • 32
    • 9444228344 scopus 로고    scopus 로고
    • Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts
    • Fry DW, Harvey PJ, Keller PR, Elliott WL, Meade M, Trachet E, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther 2004;3:1427-38.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1427-1438
    • Fry, D.W.1    Harvey, P.J.2    Keller, P.R.3    Elliott, W.L.4    Meade, M.5    Trachet, E.6
  • 33
    • 36248975284 scopus 로고    scopus 로고
    • Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication
    • Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, et al. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev 2007;21:2908-22.
    • (2007) Genes Dev , vol.21 , pp. 2908-2922
    • Aggarwal, P.1    Lessie, M.D.2    Lin, D.I.3    Pontano, L.4    Gladden, A.B.5    Nuskey, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.